Results 111 to 120 of about 124,972 (317)
CD86 is an activation receptor for NK cell cytotoxicity against tumor cells.
PLoS ONE, 2013 CTLA4Ig has been successfully used in the clinic for suppression of T cell activation. However, patients treated with CTLA4Ig experienced reduced incidence of tumors than predicted, but the underlying mechanism remains unknown.
Yanmeng Peng +12 more
doaj +1 more source
Significance of infiltration of M1 tumor-associated macrophages in hepatocellular carcinoma [PDF]
Zhongguo aizheng zazhiBackground and purpose: Tumor-associated macrophages (TAM) as the main stromal cells in the tumor microenvironment play an important role in tumor progression.
XIAO Feng, XU Tonglin, ZHU Lin, XIAO Jingwen, WU Tianqi, GU Chunyan
doaj +1 more source
EJNMMI Research, 2016 BackgroundThe inflammatory nature of atherosclerosis provides a broad range of potential molecular targets for atherosclerosis imaging. Growing interest is focused on targets related to plaque vulnerability such as the co-stimulatory molecules CD80 and ...
Romana Meletta +5 more
semanticscholar +1 more source
An In Situ Embedded B‐MOF Sponge With Shape‐Memory for All‐in‐One Diabetic Wound Therapy
Advanced Healthcare Materials, EarlyView.A smart shape‐memory sponge dressing (P1A3@B‐MOF) is developed for accelerated diabetic wound healing. It achieves pH‐responsive corelease of Zn2+ and salvianolic acid B, synergistically providing antibacterial action, repolarizing macrophages to the M2 phenotype, and promoting angiogenesis.
Hai Zhou +11 more
wiley +1 more source
C6orf10 low-frequency and rare variants in italian multiple sclerosis patients [PDF]
, 2019 In light of the complex nature of multiple sclerosis (MS) and the recently estimated contribution of low-frequency variants into disease, decoding its genetic risk components requires novel variant prioritization strategies.
Balestra, Dario +16 more
core +2 more sources
Advanced Healthcare Materials, EarlyView.Zinc‐containing bioactive glass (ZnBG) promotes diabetic wound healing by regulating macrophage extracellular traps (METs). Specifically, ZnBG reduces oxidative stress and inhibits the PAD4 and NLRP3/caspase‐1/GSDMD signaling pathways, thereby suppressing MET formation.
RuiYang Sun +11 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.An advanced microneedle patch integrating niobium carbide nanosheets and curcumin is engineered for diabetic wound healing. The system enables dual ROS scavenging and NIR‐enhanced antimicrobial activity, effectively rebalancing the oxidative microenvironment, promoting macrophage repolarization and angiogenesis, and accelerating full‐thickness wound ...
Zhi Zheng +12 more
wiley +1 more source
Regulation of T cell responses by Heme Oxygenase-1 [PDF]
, 2008 Tese de mestrado, Biologia (Biologia Molecular e Genética), 2008, Universidade de Lisboa, Faculdade de CiênciasMultiple sclerosis (MS) is a chronic inflammatory disease that affects the central nervous system (CNS).
Cortez, Eliane Cristina Monteiro
core
Artery tertiary lymphoid organs control multi-layered territorialized atherosclerosis B cell responses in aged ApoE-/- mice [PDF]
, 2016 Objective: Explore aorta B cell immunity in aged ApoE-/- mice. Approach and Results: Transcript maps, FACS, immunofluorescence analyses, cell transfers, and Ig-ELISPOT assays showed multi-layered atherosclerosis B cell responses in artery tertiary ...
Andreas J.R. Habenicht +13 more
core +1 more source
OncoTarget, 2015 HIFU has been demonstrated to enhance anti-tumor immunity, however, the mechanism of which has not been well elucidated. Emerging evidence indicates that miRNAs play important roles in immune response. In this study, we used the B16F10 melanoma allograft
Shi-mei Yuan +14 more
semanticscholar +1 more source