Results 1 to 10 of about 65,297 (255)

CD80-Mediated T-Cell Suppression by Cancer Stem-like Cells in Head and Neck Squamous Cell Carcinoma [PDF]

Cells
Neoadjuvant chemoimmunotherapy has emerged as a promising treatment strategy for head and neck squamous cell carcinoma (HNSCC). There is an urgent need to improve patient responses to this approach.
Mian Xiao, Lin Qiu, Qian Gao, Ruifeng Li, Jing Wang, Yanrui Feng, Xuefen Li, Xiyuan Ge   +7 more
doaj   +2 more sources

Immunologic Significance of CD80/CD86 or Major Histocompatibility Complex-II Expression in Thymic Epithelial Tumors [PDF]

JTO Clinical and Research Reports, 2023
Introduction: Unresectable or recurrent thymic epithelial tumors (TETs) have a poor prognosis, and treatment options are limited. This study aimed to investigate the immunologic significance of CD80/CD86 or major histocompatibility complex class II (MHC ...
Hideki Ikeda, MD, Joji Nagasaki, MD, PhD, Daiki Shimizu, MD, Yuki Katsuya, MD, PhD, Hidehito Horinouchi, MD, PhD, Yukio Hosomi, MD, PhD, Etsuko Tanji, MS, Takekazu Iwata, MD, PhD, Makiko Itami, MD, PhD, Masahito Kawazu, MD, PhD, Yuichiro Ohe, MD, PhD, Takuji Suzuki, MD, PhD, Yosuke Togashi, MD, PhD   +12 more
doaj   +5 more sources

CD80 on Human T Cells Is Associated With FoxP3 Expression and Supports Treg Homeostasis

Frontiers in Immunology, 2021
CD80 and CD86 are expressed on antigen presenting cells (APCs) and their role in providing costimulation to T cells is well established. However, it has been shown that these molecules can also be expressed by T cells, but the significance of this ...
David Sansom, Neil Halliday, Behzad Rowshanravan   +2 more
exaly   +3 more sources

Presence of CD80 and Absence of LAT in Modulating Cellular Infiltration and HSV-1 Latency [PDF]

Viruses
CD80 is the best-known costimulatory molecule for effective T cell functions. Many different reports have summarized the role of CD80 in HSV-1 and its functions in maintaining adaptive immunity, which is the main player in causing herpes stromal ...
Ujjaldeep Jaggi, Homayon Ghiasi
doaj   +2 more sources

Expression of CD80 and HLA-DR molecules on blood monocytes in patients with pulmonary tuberculosis

Медицинская иммунология, 2021
We examined expression pattern of CD80 and HLA-DR pro-inflammatory molecules on the monocytes in patients with pulmonary tuberculosis (TB), depending on the clinical form of the disease and susceptibility of the pathogen to anti-tuberculosis drugs.
E. G. Churina, A. V. Popova, O. I. Urazova, M. R. Patysheva, S. P. Chumakova, Yu. V. Kolobovnikova, E. O. Kazakova   +6 more
doaj   +1 more source

Elevated urinary CD80 excretion in children with steroid-responsive nephrotic syndrome

Biomedical and Biotechnology Research Journal, 2022
Background: Idiopathic nephrotic syndrome (INS) is one of the most common glomerular diseases in children with different pathological types and different responses to corticosteroids.
Nakysa Hooman, Hasan Otukesh, Rozita Hosseini, Azar Nickavar, Farzaneh Dastan, Mahboubeh Jafari Sarouei, Parisa Honarpisheh   +6 more
doaj   +1 more source

CD80 expression on microglia. [PDF]

, 2022
Mean fluorescence intensity of CD80 on microglia isolated from the brains of WT and Mavs-/- mice, +/- RVFV infection. (TIF)
Feliza A. Bourguet (12563078), Aimy Sebastian (823355), Doris Lam (529392), Gabriela G. Loots (12563087), Amy Rasley (18287), Nicholas R. Hum (12563075), Kristina R. Sanchez (12563084), Ashlee M. Phillips (12563081), Dina R. Weilhammer (11102115)   +8 more
core   +1 more source

Novel approaches to increase resistance to acute respiratory infections

RUDN Journal of Medicine, 2021
Relevance . Respiratory infections are the most common in the world. In order to prevent epidemics, there is a need to improve the strategies for organizing medical care and develop new approaches in order to increase the nonspecific resistance, mobilize
Svetlana V. Guryanova, Natalia A. Kudryashova, Anastasiya A. Kataeva, Bubusaira T. Orozbekova, Natalia V. Kolesnikova, Alexandr G. Chuchalin   +5 more
doaj   +1 more source

Expression of pro-inflammatory and co-stimulatory molecules on the surface of macrophages in vitro in patients with pulmonary tuberculosis

Бюллетень сибирской медицины, 2021
The aim of this study was to identify features of the expression of pro-inflammatory and co-stimulatory molecules on the surface of macrophages in vitro in patients with pulmonary tuberculosis, depending on the clinical form of the disease and ...
E. G. Churina, A. V. Sitnikova, O. I. Urazova, V. V. Novitskiy, M. R. Patysheva, P. N. Golubchikov, E. P. Stepanova   +6 more
doaj   +1 more source

CD80 expression is upregulated by TP53 activation in human cancer epithelial cells

OncoImmunology, 2021
CD80 is recognized as one of the most potent costimulatory molecules by which immune cells limit cancer progression; however, the current understanding of the regulation of its expression on human tumor cells is limited. The TP53 tumor suppressor plays a
Melania Scarpa, Chiara Marchiori, Marco Scarpa, Ignazio Castagliuolo   +3 more
doaj   +1 more source