Results 31 to 40 of about 65,297 (255)

Costimulatory Molecules CD80/86 Trigger Non-Specific Cytotoxic Cell of Nile tilapia (Oreochromis niloticus) to Kill CIK Cells

open access: yesFishes, 2022
The teleost non-specific cytotoxic cell (NCC), as the evolutionary precursors of NK cells, is an important cytotoxic cell population in the innate immune system of teleost.
Yu Huang   +7 more
doaj   +1 more source

Colocalization of PD-L1 on DCs to CD80 expressed by HSV-CD80 and its effect on virus replication. [PDF]

open access: yes, 2014
A) FACS analyses of infected WT DCs. Subconfluent monolayers of DCs isolated from WT C57BL/6 mice were infected with 1 PFU/cell of HSV-CD80, parental virus, or mock infected.
Omid Akbari (390206)   +9 more
core   +1 more source

Triggering of lymphocytes by CD28, 4-1BB, and PD-1 checkpoints to enhance the immune response capacities

open access: yesPLoS ONE, 2022
Tumor infiltrating lymphocytes (TILs) usually become exhausted and dysfunctional owing to chronic contact with tumor cells and overexpression of multiple inhibitor receptors.
Elina Kaviani   +5 more
doaj   +2 more sources

CD80 expression promotes immune surveillance in Barrett’s metaplasia

open access: yesOncoImmunology, 2019
Esophageal adenocarcinoma (EAC) is the final step of a pathway starting with esophageal reflux disease, Barrett’s metaplasia and Barrett’s dysplasia.
Melania Scarpa   +13 more
doaj   +1 more source

CD80 preferentially control lethality and inflammation in CLP. [PDF]

open access: yes, 2013
Panel A-WT (n = 20) and CD80−/− (N = 15) and CD86−/− (N = 15) underwent CLP and were monitored for survival ...
Hiroshi Kobayashi (23858)   +9 more
core   +1 more source

CD68, CD80, CD86 and PD-L1 staining in liver biopsies. [PDF]

open access: yes, 2016
Biopsies from HBV-infected and control individuals were stained with mouse anti-human CD68 and rabbit anti-human CD80, CD86 or PD-L1 Abs. Representative photomicrographs showing (A) CD68 red staining indicating CD68+ cells and (B-D) CD80, CD86 or PD-L1 ...
Crystal Y. Koh (2605771)   +9 more
core   +1 more source

Tissue Levels of CD80, CD163 and CD206 and Their Ratios in Periodontal and Peri-Implant Health and Disease

open access: yesCurrent Issues in Molecular Biology, 2022
This study aimed to compare tissue levels of CD80 (pro-inflammatory macrophage-related surface marker), CD163, and CD206 (anti-inflammatory macrophage-related surface markers), and their ratios in periodontal and peri-implant health and disease ...
Mustafa Yilmaz   +4 more
doaj   +1 more source

PMN membranes disassociate IRAK-M from CD80. [PDF]

open access: yes, 2013
Macrophages were treated with PMN lipid rafts for various times Panel A. Co-IP demonstrates CD80 binds IRAK-M in resting PMA differentiated THP-1 macrophages, lane 1. One hour after lipid raft treatment IRAK-M disassociates from CD80, lane 2.
Hiroshi Kobayashi (23858)   +9 more
core   +1 more source

Differential role for CD80 and CD86 in the regulation of the innate immune response in murine polymicrobial sepsis.

open access: yesPLoS ONE, 2009
BackgroundInflammation in the early stages of sepsis is governed by the innate immune response. Costimulatory molecules are a receptor/ligand class of molecules capable of regulation of inflammation in innate immunity via macrophage/neutrophil contact ...
Anna Nolan   +9 more
doaj   +1 more source

CD40-mediated CD80 upregulation is defective in HOIP-deficient cells. [PDF]

open access: yes, 2013
Cells were incubated for 72 hrs with an isotype control antibody (left) or anti-CD40 antibody (right) and then stained for expression of CD80 (filled profiles indicate staining with anti-CD80 antibody; open profiles are staining with an isotype control ...
John D. Colgan (346935)   +3 more
core   +1 more source

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