Results 31 to 40 of about 69,003 (290)
Calreticulin arms NK cells against leukemia
OncoImmunology, 2020 Calreticulin (CALR) exposed on the surface of cancer cells succumbing to therapy delivers robust phagocytic signals that support the activation of adaptive anticancer immune responses. Recent data from our group demonstrate that spontaneous CARL exposure
Jitka Fucikova +3 more
doaj +1 more source
Human Vaccines & Immunotherapeutics, 2020 Triple-negative breast cancer (TNBC) afflicts women at a younger age than other breast cancers and is associated with a worse clinical outcome. This poor clinical outcome is attributed to a lack of defined targets and patient-to-patient heterogeneity in ...
Christopher D. Pack +11 more
doaj +1 more source
Extending the B7 (CD80) gene family [PDF]
Protein Science, 1994 AbstractB7‐1 and B7‐2 are members of the immunoglobulin superfamily (IgSF) and important regulators of T cell‐mediated immune responses. Despite sharing only limited sequence identity, B7‐1 and B7‐2 bind common receptors, CD28 and CTLA‐4, on T cells and have similar functional properties.
P S, Linsley +3 more
openaire +2 more sources
CD80-CD28 signaling controls the progression of inflammatory colorectal carcinogenesis [PDF]
, 2015 In patients with ulcerative colitis (UC) the cumulative risk of colon cancer is lower than the actual rate of dysplasia suggesting an efficient immune surveillance mechanism.
Carlo Castoro1 +17 more
core +1 more source
Fishes, 2022 The teleost non-specific cytotoxic cell (NCC), as the evolutionary precursors of NK cells, is an important cytotoxic cell population in the innate immune system of teleost.
Yu Huang +7 more
doaj +1 more source
CD80 on Human T Cells Is Associated With FoxP3 Expression and Supports Treg Homeostasis
Frontiers in Immunology, 2021 CD80 and CD86 are expressed on antigen presenting cells (APCs) and their role in providing costimulation to T cells is well established. However, it has been shown that these molecules can also be expressed by T cells, but the significance of this ...
Blagoje Soskic +10 more
doaj +1 more source
PLoS ONE, 2022 Tumor infiltrating lymphocytes (TILs) usually become exhausted and dysfunctional owing to chronic contact with tumor cells and overexpression of multiple inhibitor receptors.
Elina Kaviani +5 more
doaj +2 more sources
CD80 expression promotes immune surveillance in Barrett’s metaplasia
OncoImmunology, 2019 Esophageal adenocarcinoma (EAC) is the final step of a pathway starting with esophageal reflux disease, Barrett’s metaplasia and Barrett’s dysplasia.
Melania Scarpa +13 more
doaj +1 more source
Current Issues in Molecular Biology, 2022 This study aimed to compare tissue levels of CD80 (pro-inflammatory macrophage-related surface marker), CD163, and CD206 (anti-inflammatory macrophage-related surface markers), and their ratios in periodontal and peri-implant health and disease ...
Mustafa Yilmaz +4 more
doaj +1 more source
DAC educated CD80 positive, but not CD80 negative EL4 cells induce T cell responses.
, 2013 (A) EL4 cells were treated with DAC. CD80+ and CD80− EL4 cells were separated by flow cytometry-based sorting. Flow cytometric analysis of CD80 expression in EL4 cells before and after sorting is shown.
Yi Ding (172783) +19 more
core +1 more source