Results 31 to 40 of about 71,028 (295)

Costimulatory Molecules CD80/86 Trigger Non-Specific Cytotoxic Cell of Nile tilapia (Oreochromis niloticus) to Kill CIK Cells

open access: yesFishes, 2022
The teleost non-specific cytotoxic cell (NCC), as the evolutionary precursors of NK cells, is an important cytotoxic cell population in the innate immune system of teleost.
Yu Huang   +7 more
doaj   +1 more source

Immunolocalization of CD80 and CD86 in Non-Small Cell Lung Carcinoma: CD80 as a Potent Prognostic Factor

open access: yesACTA HISTOCHEMICA ET CYTOCHEMICA, 2022
It has been demonstrated that tumor cells express programed cell death protein 1 (PD-L1) to escape T lymphocytes that express programed cell protein 1 (PD-1), and PD-1/PD-L1 immune checkpoint inhibitors have been regarded in lung cancer patients. CD80 and CD86 are members of B7 superfamily which regulates T lymphocyte activation and tolerance. However,
Sato, Takashi   +9 more
openaire   +3 more sources

CD80 expression promotes immune surveillance in Barrett’s metaplasia

open access: yesOncoImmunology, 2019
Esophageal adenocarcinoma (EAC) is the final step of a pathway starting with esophageal reflux disease, Barrett’s metaplasia and Barrett’s dysplasia.
Melania Scarpa   +13 more
doaj   +1 more source

Tissue Levels of CD80, CD163 and CD206 and Their Ratios in Periodontal and Peri-Implant Health and Disease

open access: yesCurrent Issues in Molecular Biology, 2022
This study aimed to compare tissue levels of CD80 (pro-inflammatory macrophage-related surface marker), CD163, and CD206 (anti-inflammatory macrophage-related surface markers), and their ratios in periodontal and peri-implant health and disease ...
Mustafa Yilmaz   +4 more
doaj   +1 more source

CD80 blockade preferentially improves survival after CLP.

open access: yes, 2013
Panel A-WT C57BL/6 mice were administered either 250 µg anti-CD80, anti -CD86 or both 4 hrs prior to CLP and monitored for survival (n = 10/group). Data from anti -CD80/86 has been published previously [18]. P = 0.002 for anti-CD80 vs. control.
Hiroshi Kobayashi (23858)   +9 more
core   +1 more source

Expression of CD80 by HSV-CD80 in infected DCs.

open access: yes, 2014
A) Detection of HSV-1 gC in infected DCs. Subconfluent monolayers of DCs isolated from C57BL/6 mice were infected with 1 PFU/cell of HSV-CD80, parental virus, or mock infected.
Omid Akbari (390206)   +9 more
core   +1 more source

CD86 Is a Selective CD28 Ligand Supporting FoxP3+ Regulatory T Cell Homeostasis in the Presence of High Levels of CTLA-4

open access: yesFrontiers in Immunology, 2020
CD80 and CD86 are expressed on antigen presenting cells and are required to engage their shared receptor, CD28, for the costimulation of CD4 T cells. It is unclear why two stimulatory ligands with overlapping roles have evolved.
Neil Halliday   +12 more
doaj   +1 more source

DAC educated CD80 positive, but not CD80 negative EL4 cells induce T cell responses.

open access: yes, 2013
(A) EL4 cells were treated with DAC. CD80+ and CD80− EL4 cells were separated by flow cytometry-based sorting. Flow cytometric analysis of CD80 expression in EL4 cells before and after sorting is shown.
Yi Ding (172783)   +19 more
core   +1 more source

TLR-mediated albuminuria needs TNFα-mediated cooperativity between TLRs present in hematopoietic tissues and CD80 present on non-hematopoietic tissues in mice

open access: yesDisease Models & Mechanisms, 2016
Transient albuminuria induced by pathogen-associated molecular patterns (PAMPs) in mice through engagement of Toll-like receptors (TLRs) is widely studied as a partial model for some forms of human nephrotic syndrome (NS).
Nidhi Jain   +11 more
doaj   +1 more source

Level of HSV-1 immediate early, early, and CD80 in HSV-CD80 infected DCs.

open access: yes, 2014
Subconfluent monolayers of DCs from C57BL/6 mice were infected with 1 PFU/cell of HSV-CD80 or parental virus as in Fig. 1. For ICP-0 and TK measurements, cells were isolated 4, 8, and 12 hr PI, while for CD80 measurements cells were harvested 2, 4, 8, 12,
Omid Akbari (390206)   +9 more
core   +1 more source

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