Results 41 to 50 of about 71,028 (295)

Urinary CD80 and Serum suPAR as Biomarkers of Glomerular Disease among Adults in Brazil

Diagnostics, 2023
Introduction: Urinary CD80 has been shown to have good specificity for minimal change disease (MCD) in children. However, the investigation of circulating factors such as soluble urokinase plasminogen activator receptor (suPAR) as biomarkers of focal ...
Renata de Cássia Zen, Wagner Vasques Dominguez, Ivone Braga, Luciene Machado dos Reis, Lectícia Barbosa Jorge, Luis Yu, Viktoria Woronik, Cristiane Bitencourt Dias   +7 more
doaj   +1 more source

Association of CD24, CD27, and co-stimulatory molecules CD80 immunological marker expression on B-cells of human peripheral blood with development of celiac disease

Iraqi Journal of Hematology
BACKGROUND: B-cells express a variety of clusters of differentiation markers during development. These markers determine the basic function of the immune phenotype specific to B-cells.
Rahab Abd-Ali Al-Madany, Noor Abdulameer Oudah   +1 more
doaj   +1 more source

Usefulness of the cytokines expression of Th1/Th2/Th17 and urinary CD80 excretion in adult-onset minimal change disease [PDF]

PeerJ, 2020
Background Minimal change disease (MCD) is a common form of nephrotic syndrome in adults. However, the molecular mechanism underlying the pathogenesis of MCD remains incompletely understood.
Ping Chen, Yan Chen, Maoqing Jiang, Yijun Mo, Huanhuan Ying, Xun Tang, Jun Zhang   +6 more
doaj   +2 more sources

Expression of CD80/MHCII, CD3 and GATA-3/CD3 in SL culture.

, 2023
Expression of CD80 in MHCII+ (CD80/MHCII) leukocytes (A), CD3 (B) and GATA-3 in TCD3+ leukocytes (GATA-3/CD3) (C). Splenic leukocytes from control (healthy dogs) and CanL (dogs naturally infected by L.
Gabriela Torres Rebech (6053297), Valéria Marçal Felix de Lima (8115269), Sidnei Ferro Costa (8115260), Marilene Oliveira dos Santos (12290053), Jaqueline Poleto Bragato (5488034), Flávia de Rezende Eugênio (8115263), Jéssica Henrique de Freitas (12290050), Paulo Sérgio Patto dos Santos (12290059), Matheus Fujimura Soares (14526507)   +8 more
core   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

CD80 and CTLA-4 as diagnostic and prognostic markers in adult-onset minimal change disease: a retrospective study [PDF]

PeerJ, 2018
Background Minimal change disease (MCD) is a form of idiopathic nephrotic syndrome. Compared to children, adult-onset MCD patients are reported to have delayed responses to glucocorticoid treatment.
Bing Zhao, Hui Han, Junhui Zhen, Xiaowei Yang, Jin Shang, Liang Xu, Rong Wang   +6 more
doaj   +2 more sources

Biomimetic Hybrid‐Membrane Nanoreactor for Deep‐Seated Photodynamic Immunotherapy of Hepatocellular Carcinoma via Dual Catalysis‐Enhanced ROS Amplification and cGAS‐STING Activation

Advanced Functional Materials, EarlyView.
UCNP@MnOx‐Hyp@HRM (UMHM) enables tumor targeting and accumulation. Under 808 nm NIR irradiation, PDT/CDT synergistically triggers ICD and cGAS–STING immunity for deep hepatocellular carcinoma therapy. ABSTRACT Photodynamic therapy (PDT) is promising against hepatocellular carcinoma (HCC).
Wen Li, Jianzhang Luo, Pei Lu, Dongqing Liu, Huijun Yi, Xiaoyuan Yi, Bixia Chi, Wen Chen, Qingyu Zeng, Feifei He, Liyan Wang   +10 more
wiley   +1 more source

Epithelial CD80 promotes immune surveillance of colonic preneoplastic lesions and its expression is increased by oxidative stress through STAT3 in colon cancer cells

Journal of Experimental & Clinical Cancer Research, 2019
Background One of the most potent costimulatory molecules involved in the recognition and killing of tumor cells is CD80. However, its role and the molecular mechanisms regulating its expression in sporadic colorectal carcinogenesis remain elusive. Here,
Chiara Marchiori, Melania Scarpa, Andromachi Kotsafti, Susan Morgan, Matteo Fassan, Vincenza Guzzardo, Andrea Porzionato, Imerio Angriman, Cesare Ruffolo, Stefania Sut, Stefano Dall’Acqua, Romeo Bardini, Raffaele De Caro, Carlo Castoro, Marco Scarpa, Ignazio Castagliuolo   +15 more
doaj   +1 more source

Engineering Antigen Density on M13 Bacteriophage for Personalized Nanovaccine

Advanced Healthcare Materials, EarlyView.
Increasing antigen density on the phage capsid impacts phage uptake and antigen cross‐presentation by antigen‐presenting cells, leading to enhanced activation of antitumor CD8+ T cells in the draining lymph nodes. These activated CD8+ T cells subsequently recognize the antigen‐expressing tumors and mediate their specific cytotoxic killing, thereby ...
Shengnan Huang, Allison Madow, Jack Rudrum, Huaiyao Peng, Hao Nghi Luu, Peiyan Dong, Jifa Qi, Angela M. Belcher   +7 more
wiley   +1 more source

Evaluation of Some Immunological Markers in Pregnant Women Infected with Cytomegalovirus in Kirkuk, Iraq

Medical Journal of Babylon
Background: Both innate and adaptive immunological responses may be activated by cytomegalovirus (CMV) infection, leading to significant reactions later in the course of the illness. Innate immune components, which react fast and nonspecifically, combine
Zena Muayad Nooruldeen, Mohammed Yawoz Nooruldeen   +1 more
doaj   +1 more source