Results 151 to 160 of about 9,042 (190)

Integrated single-cell and bulk transcriptomic analyses reveal cDC1-centered ubiquitination dysregulation and identify UBE2F as a critical regulator in sepsis. [PDF]

Front Immunol
Li C, Han Y, Zheng Z, Huang C, Liu Z, Zhou J, Yang R, Wu J.   +7 more
europepmc   +1 more source

DYRK1A enhances antitumor immunity in type 1 conventional dendritic cells via mTORC1 activation. [PDF]

J Clin Invest
Wang H, Jiang H, He S, Ren S, Li H, Liu W, Zhou C, Zhu P, Chen K, Cao W, Qin Y, Du D, Xiao N, Huang H, Ko CJ, Zheng Y, Wang B, Zou Q, Shi JH, Li X, Jie Z.   +20 more
europepmc   +1 more source

Single cell transcriptomics reveals dendritic cell subsets in bovine afferent lymph and immune cell-resolved responses to BCG vaccination. [PDF]

Front Immunol
Sukmak R, Mathie HA, Taylor RS, Sun J, Shih B, Bell CR, Gray M, Macqueen DJ, Hope JC.   +8 more
europepmc   +1 more source

Tertiary lymphoid structure topotypes in intrahepatic cholangiocarcinoma: spatial immunity, checkpoint-response associations, and therapeutic reprogramming. [PDF]

Front Immunol
Yuan Z, Li X, Cheng Q, Gao J.
europepmc   +1 more source

TopBP1 orchestrates PU.1-IRF8 transcriptional programming of dendritic cell differentiation and Flt3L-driven tumor immunity. [PDF]

Exp Mol Med
Cha MS, Kang MH, Lee J, Hong J, Jeong YS, Bae YS, Lee H, Park SH, Bae YS.   +8 more
europepmc   +1 more source

Zbtb10 Transcription Factor Is Crucial for Murine cDC1 Activation and Cytokine Secretion

European Journal of Immunology, 2021
Abstract Dendritic cell (DC) activation and cytokine production is tightly regulated. In this study, we found that Zbtb10 expression is activation dependent and it is essential for the immunogenic function of cDC1.
Sunil K Raghav, Viplov Kumar Biswas, Arup Ghosh   +2 more
exaly   +5 more sources

IRF8 Deficiency Induces the Transcriptional, Functional, and Epigenetic Reprogramming of cDC1 Into the cDC2 Lineage

Immunity, 2022
Conventional dendritic cells (cDCs) consist of two major functionally and phenotypically distinct subsets, cDC1 and cDC2, whose development is dependent on distinct sets of transcription factors.
Allan Mowat, Thorsten Joeris, Knut Kotarsky   +2 more
exaly   +2 more sources