Results 61 to 70 of about 27,912 (176)

Suppl. Fig. S5 from Characterization of Novel Derivatives of MBQ-167, an Inhibitor of the GTP-binding Proteins Rac/Cdc42 [PDF]

, 2023
Julia I. Medina, Ailed Cruz‐Collazo, María del Mar Maldonado, Tatiana Matos Gascot, Luis D. Borrero-García, Mariana Cooke, Marcelo G. Kazanietz, Eliud Hernandez O'Farril, Cornelis P. Vlaar, Suranganie Dharmawardhane   +9 more
openalex   +2 more sources

Regulation of protein transport from the Golgi complex to the endoplasmic reticulum by CDC42 and N-WASP. [PDF]

, 2002
Actin is involved in the organization of the Golgi complex and Golgi-to-ER protein transport in mammalian cells. Little, however, is known about the regulation of the Golgi-associated actin cytoskeleton.
Ballesta, José, Durán Serrano, Juan Manuel, Egea Guri, Gustavo, Luna Moñux, Ana, Martínez-Menárguez, José Ángel, Matas Guadix, Olga Belén, Mato Matute, Maria Eugènia, Way, Michael   +7 more
core   +2 more sources

Tumour Cell Size Control and Its Impact on Tumour Cell Function

Cell Proliferation, Volume 58, Issue 12, December 2025.
The regulatory mechanism of the size of tumour cells and its impact on the functions of tumour cells, as well as a summary of potential therapeutic targets for the corresponding mechanisms. ABSTRACT Cell size is an important component of cell morphological characteristics.
Min Zhou, Mei Zhou, Yang Jin
wiley   +1 more source

Suppl. Fig. S7 from Characterization of Novel Derivatives of MBQ-167, an Inhibitor of the GTP-binding Proteins Rac/Cdc42 [PDF]

, 2023
Julia I. Medina, Ailed Cruz‐Collazo, María del Mar Maldonado, Tatiana Matos Gascot, Luis D. Borrero-García, Mariana Cooke, Marcelo G. Kazanietz, Eliud Hernandez O'Farril, Cornelis P. Vlaar, Suranganie Dharmawardhane   +9 more
openalex   +2 more sources

Reciprocal regulation of PKA and rac signaling [PDF]

, 2013
Activated G protein-coupled receptors (GPCRs) and receptor tyrosine kinases relay extracellular signals through spatial and temporal controlled kinase and GTPase entities.
A. Riml, Baillie, Bhola, Birukova, Cook, Cuevas, Daaka, Delcourt, Dewire, Dorsam, Dumaz, E. Stefan, Eblen, G. S. Baillie, Gerits, Gloerich, Hafner, Hoffmann, Howe, Jaffe, K. R. Liedl, Kinderman, King, Kraynov, Kumar, Ligr, Malbon, Manser, Molli, Nika, Pierce, R. G. Huber, Sahai, Sch  fer, Scott, Smith, Stefan, Stork, T. Valovka, Taylor, Thaker, V. A. Bachmann, Wang, Wennerberg, Wong, Zenke, Zhang, Zhao   +47 more
core   +1 more source

The Cool-2/α-Pix Protein Mediates a Cdc42-Rac Signaling Cascade [PDF]

, 2005
Background:Cloned-out of library-2 (Cool-2)/PAK-interactive exchange factor (α-Pix) was identified through its ability to bind the Cdc42/Rac target p21-activated kinase (PAK) and has been implicated in certain forms of X-linked mental retardation as well
Baird, Dan, Feng, Qiyu, Cerione, Richard A.   +2 more
core   +3 more sources

Glycoproteomics and Its Role in Understanding Bacterial O‐Linked Glycosylation

PROTEOMICS, Volume 25, Issue 21-22, Page 160-176, November 2025.
ABSTRACT Protein glycosylation is now recognized as a ubiquitous process observed in all domains of life. Within bacterial species, carbohydrates can be attached to multiple residues with glycosylation of serine, threonine, or tyrosine residues via their hydroxyl side chains referred to as O‐linked glycosylation.
Kristian I. Karlic, Hamza Tahir, Nichollas E. Scott   +2 more
wiley   +1 more source

Enabling systemic identification and functionality profiling for Cdc42 homeostatic modulators

Communications Chemistry
Maintaining body homeostasis is the ultimate key to health. There are rich resources of bioactive materials for the functionality of homeostatic modulators (HMs) from both natural and synthetic chemical repertories1–3.
Satyaveni Malasala, Fereshteh Azimian, Yan-Hua Chen, Jeffery L. Twiss, Christi Boykin, Shayan Nik Akhtar, Qun Lu   +6 more
doaj   +1 more source

Suppl. Fig. S2 from Characterization of Novel Derivatives of MBQ-167, an Inhibitor of the GTP-binding Proteins Rac/Cdc42 [PDF]

, 2023
Julia I. Medina, Ailed Cruz‐Collazo, María del Mar Maldonado, Tatiana Matos Gascot, Luis D. Borrero-García, Mariana Cooke, Marcelo G. Kazanietz, Eliud Hernandez O'Farril, Cornelis P. Vlaar, Suranganie Dharmawardhane   +9 more
openalex   +2 more sources

Exosomes containing HIV protein Nef reorganize lipid rafts potentiating inflammatory response in bystander cells. [PDF]

, 2019
HIV infection has a profound effect on "bystander" cells causing metabolic co-morbidities. This may be mediated by exosomes secreted by HIV-infected cells and containing viral factors.
Brichacek, Beda, Bukrinsky, Michael, Ditiatkovski, Michael, Dragoljevic, Dragana, Dubrovsky, Larisa, Fu, Ying, Hoang, Anh, Horvath, Anelia, Low, Hann, Meikle, Peter J, Miller, Yury I, Mukhamedova, Nigora, Murphy, Andrew, Ohkawa, Ryunosuke, Pushkarsky, Tatiana, Sviridov, Dmitri   +15 more
core   +3 more sources