Results 101 to 110 of about 138,770 (367)

DNA resection in eukaryotes: deciding how to fix the break [PDF]

, 2010
DNA double-strand breaks are repaired by different mechanisms, including homologous recombination and nonhomologous end-joining. DNA-end resection, the first step in recombination, is a key step that contributes to the choice of DSB repair.
A Aguilera, A Jazayeri, A Jazayeri, A Penkner, AA Sartori, AH McKee, AV Nimonkar, B Gu, BB Hopkins, BM Lengsfeld, BO Krogh, C Uanschou, C Zierhut, CF Cheok, CJ Lord, D Mantiero, D Nakada, DA Bressan, DO Warmerdam, E Baroni, EP Mimitou, F Lazzaro, G Chinnadurai, G Ira, G Wu, I Morin, J Buis, J Falck, JC Harrison, JH Barlow, JH Kim, JP Duxin, K Lee, K Shimada, KM Trujillo, L Chen, L Chen, L Maringele, L Zheng, M Clerici, M Clerici, M Grenon, M Lisby, M McVey, MF Lavin, MH Yun, MJ Neale, MR Lieber, O Limbo, P Huertas, P Huertas, Pablo Huertas, PL Chen, PT Tran, R Linding, R Waltes, RR Khakhar, RS Williams, S Gravel, S Liao, S Moreau, S Prinz, SH Bae, SK Amundsen, T Usui, TH Stracker, TT Paull, WS Dynan, X Yu, X Yu, Y Akamatsu, Y Aylon, Y Zhang, Z Horejsí, Z Zhu   +74 more
core   +1 more source

Poligromorph Materials: Shape Morphing Functional Polyvinyl Alcohol/Maleic Anhydride Ethylene‐Propylene/Carbon Composites in Aqueous and Hydrocarbon‐Based Media

Advanced Intelligent Systems, EarlyView.
Hygromorphic materials, such as pinecone scales, respond to humidity changes. This study presents poligromorphic composites—composed of carbon fibers (CFs), polyvinyl alcohol (PVA), and maleic anhydride ethylene‐propylene (MA‐EPR)—that react to water, humidity, and hydrocarbons.
Liia Buhhanevits, Hesam Ramezani, Charles de Kergariou, Fabrizio Scarpa, Neil Fox   +4 more
wiley   +1 more source

Genome-wide identification, evolutionary and expression analysis of the cyclin-dependent kinase gene family in peanut

BMC Plant Biology, 2023
Background Cyclin-dependent kinases (CDKs) are a predominant group of serine/threonine protein kinases that have multi-faceted functions in eukaryotes. The plant CDK members have well-known roles in cell cycle progression, transcriptional regulation, DNA
Gokul Babu S, Deependra Singh Gohil, Swarup Roy Choudhury   +2 more
doaj   +1 more source

The expected convex hull trimmed regions of a sample [PDF]

, 2006
Given a data set in the multivariate Euclidean space, we study regions of central points built by averaging all their subsets with a fixed number of elements.
Cascos, Ignacio
core   +1 more source

Rapid Breast Cancer Disease Progression Following Cyclin Dependent Kinase 4 and 6 Inhibitor Discontinuation. [PDF]

, 2017
Background: CDK 4 and 6 inhibitors (CDK4/6i), which arrest unregulated cancer cell proliferation, show clinical efficacy in breast cancer. Unexpectedly, a patient treated on a CDK4/6i-based trial, as first-line therapy in metastatic breast cancer ...
Abouharb, Sausan, Bashour, Sami I, Brown, Powel H, Doostan, Iman, Ibrahim, Nuhad K, Karuturi, Meghan, Keyomarsi, Khandan, Koenig, Kimberly B, Litton, Jennifer K, Moulder-Thompson, Stacy L, Tripathy, Debasish, Ueno, Naoto T, Valero, Vicente   +12 more
core   +2 more sources

The efficacy and usability of motivational interviewing just‐in‐time trainings for youth mentors

American Journal of Community Psychology, EarlyView.
Abstract Using youth mentors to deliver evidence‐based psychosocial services has been proposed to increase the reach of treatments, in part given the affordability and ubiquity of mentors in youth settings. Further, tests of mentor‐delivered motivational interviewing (MI) have shown increases in youth mentees' academic performance and wellbeing.
Mackenzie J. Hart, Samuel D. McQuillin, Aidyn Iachini, Daniel K. Cooper, Mark D. Weist   +4 more
wiley   +1 more source

Prevalence and associated factors for climatic droplet keratopathy in Kazakhs adults: a cross-sectional study in Tacheng, Xinjiang, China

BMC Ophthalmology, 2021
Background Investigation of the prevalence of climatic droplet keratopathy (CDK) in Tacheng, Xinjiang, China. Methods A total of 1030 participants, in their 40s or older, from the Kazakh ethnic group in Tacheng, were randomly sampled by stratification ...
Zhixiang Hua, Xiaoyan Han, Guoqing Li, Li Lv, Xiaolan He, Laman Gu, Jianfeng Luo, Jin Yang   +7 more
doaj   +1 more source

Design Environments for Complex Systems [PDF]

, 2003
The paper describes an approach for modeling complex systems by hiding as much formal details as possible from the user, still allowing verification and simulation of the model.
Priami, Corrado
core  

Modulation of plant growth in vivo and identification of kinase substrates using an analog-sensitive variant of CYCLIN-DEPENDENT KINASE A;1 [PDF]

, 2016
BACKGROUND: Modulation of protein activity by phosphorylation through kinases and subsequent de-phosphorylation by phosphatases is one of the most prominent cellular control mechanisms.
Dissmeyer, N., Hammann, P., Harashima, H., Kramer, K., Nakagami, H., Nomura, Y., Schnittger, A.   +6 more
core   +2 more sources

Artificial intelligence modelling of tyrosine kinase inhibitors at risk of malabsorption and bioavailability‐enhancing strategies

British Journal of Clinical Pharmacology, EarlyView.
Aims The study aims to predict and improve the absorption of tyrosine kinase inhibitors (TKIs) in patients with malabsorption issues, particularly those who have undergone bariatric surgery or are using proton‐pump inhibitors. The research involves 2 main components: the development of an artificial intelligence (AI) model to identify TKIs that are ...
Daan W. Huntjens, Olivier J. M. Béquignon, Stefanie D. Krens, Mark Löwenberg, Martine E. D. Chamuleau, Remco J. Molenaar, Anita M. G. Kramers, Marianne A. Kuijvenhoven, Imke H. Bartelink   +8 more
wiley   +1 more source