Multi-analytical and biological insights into Malcolmia grandiflora Kuntze. [PDF]
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A Decade After Approval of the First CDK4/6 Inhibitor: A Look Back at Palbociclib's Journey from Discovery to Approval and What's Next in CDK Inhibition in Breast Cancer. [PDF]
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Influence of stage-specific and location-related intratumoral microbiota on prognosis and metabolic reprogramming in non-small cell lung cancer. [PDF]
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[Expression of Concern] CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas. [PDF]
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Cell Cycle Plasticity and Heterogeneity: An Underappreciated Feature of Cancer and Treatment Response. [PDF]
Knudsen ES, O'Connor TN, Witkiewicz AK.
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Regulation of cell proliferation by a novel feedback system on Cdk function
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Recent advances on cyclins, CDKs and CDK inhibitors
Trends in Cell Biology, 1997In eukaryotes, cell division is controlled by cyclin-dependent kinases (CDKs). Here we summarize a few new developments on the regulation of the cell cycle by CDK-cyclin complexes. We have focused on three aspects in which there has been recent progress: the structural analysis of these complexes, the phenotypes of mice carrying knockouts of CDK ...
C, Martin-Castellanos, , Moreno
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The connections between cancer and the basic machinery of the cell cycle have taken a surprisingly long time to become apparent. However, the past 2 years has seen a dramatic increase in the number of cell cycles regulators that have been implicated as either protooncogenes or as tumour suppressor genes.
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