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Analysis of the CDKN2A, CDKN2B and CDK4 Genes in 48 Australian Melanoma Kindreds [PDF]
Oncogene, 1997 Germline mutations within the cyclin-dependent kinase inhibitor 2A (CDKN2A) gene and one of its targets, the cyclin dependent kinase 4 (CDK4) gene, have been identified in a proportion of melanoma kindreds. In the case of CDK4, only one specific mutation,
Pamela M. Pollock +2 more
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Journal of Clinical Medicine, 2020 The mutation of cyclin dependent kinase inhibitor 2A (CDKN2A) is frequently found in pancreatic ductal adenocarcinoma (PDAC). However, its prognostic and therapeutic roles in PDAC have not been extensively investigated yet.
Jiunn-Chang Lin +2 more
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Human Genetics, 2016 The risk of pancreatic cancer (PC) is increased in melanoma-prone families but the causal relationship between germline CDKN2A mutations and PC risk is uncertain, suggesting the existence of non-CDKN2A factors.
Belynda Hicks +2 more
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CDKN2A Deletion Remodels Lipid Metabolism to Prime Glioblastoma for Ferroptosis
Cancer Cell, 2023Kevin J. Williams +2 more
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CDKN2A/B Homozygous Deletions in Astrocytomas: A Literature Review
Current Issues in Molecular Biology, 2023Adrian Lee +2 more
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Bi-Allelic Loss of CDKN2A Initiates Melanoma Invasion via BRN2 Activation
Cancer Cell, 2018Thomas Botton, Alan Shain, Iwei Yeh
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The Prognostic Value of CDKN2A Hypermethylation in Colorectal Cancer: A Meta-Analysis
British Journal of Cancer, 2013X Xing
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Implications of Genetic and Epigenetic Alterations of CDKN2A (p16INK4a) in Cancer
EBioMedicine, 2016Bu Young Choi, Mee-Hyun Lee, Zigang Dong
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Frequent Alterations in p16/CDKN2A Identified by Immunohistochemistry and FISH in Chordoma
Journal of Pathology: Clinical Research, 2020Adrienne M Flanagan +2 more
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