Results 211 to 220 of about 61,476 (246)

Spatial evidence of senescence-associated pathology after myocardial infarction in humans and therapeutic targeting in ageing mice

Redgrave RE, Zormpas E, Mathison L, Encina MC, Spyridopoulos I, Cockell SJ, Tual-Chalot S, Richardson GD.   +7 more
europepmc   +1 more source

MEK inhibitors in NF1-associated high-grade glioma: partial responses and outcomes from a single-institution cohort and literature review. [PDF]

J Neurooncol
Yu MC, Hsi AH, Adnan A, Knight SR, McCutcheon IE, Slopis JM, Kamiya-Matsuoka C.   +6 more
europepmc   +1 more source

The Baseline Molecular Profile of Late Relapse: Identifying Drivers of Delayed Recurrence in DLBCL

Hematological Oncology, Volume 44, Issue 6, November 2026.
Michal Masar, Joseph P. Novak, Janek S. Walker, Prokop Vodicka, Abigail R. Dropik, Zilin Xianyu, Matthew J. Maurer, Thomas M. Habermann, Eric Mou, Rebecca L. King, Kerstin Wenzl, Thomas E. Witzig, Stephen M. Ansell, Pavel Klener, James R. Cerhan, Marek Trneny, Yucai Wang, Magdalena Klanova, Anne J. Novak   +18 more
wiley   +1 more source

Microbial and Metabolic Correlates of Endometrial Dysfunction in Polycystic Ovary Syndrome: A Translational Study

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 12, Page 2092-2102, November 2026.
ABSTRACT Objective Women with polycystic ovary syndrome (PCOS) exhibit a substantially increased risk of miscarriage, yet the underlying mechanisms remain inadequately understood. This study aimed to investigate whether specific gut microbial dysbiosis and metabolic disturbance are associated with and may potentially contribute to endometrial ...
Mengyu Jing, Xi Chen, Meiyan Jiang, Huiya Fang, Xiaoming Zhu, Xuejing Jin, Yonghui Jiao, Ningning Hou, Weiwei Gong, Aixia Liu   +9 more
wiley   +1 more source

Digital PCR for Detecting Loss of BAP1 and MTAP in Pleural Fluids of Mesothelioma Patients: Perspectives in the Diagnosis. [PDF]

Pathol Int
Rosini G, Alì G, Bruno R, Cipollini M, Foddis R, Celi A, Silvestri R, Rea F, Aprile V, Lucchi M, Gemignani F, Landi S.   +11 more
europepmc   +1 more source

Cellular Senescence Dysregulates Antiviral Interferon Responses in Idiopathic Pulmonary Fibrosis

Aging Cell, Volume 25, Issue 11, November 2026.
Senescent idiopathic pulmonary fibroblasts (IPF) lung fibroblasts are transcriptomically uncoupled from a functional response to virus relative to healthy (HLF) lung fibroblasts. HLF lung fibroblasts require viral effectors STAT1 or IRF3 to enact a viral response while IPF lung fibroblasts do not rely on these axes in response to virus.
Jun‐Wei B. Hughes, Yasmina Reisser, Franziska Hornung, Tyler A. U. Hilsabeck, Fiona Senchyna, Ana L. Coelho, Tsung‐Che Ho, Kevin Schneider, David Furman, Cory M. Hogaboam, Claude Jourdan Le Saux, Pierre‐Yves Desprez, Stefanie Deinhardt‐Emmer   +12 more
wiley   +1 more source

Report of Multilocus Inherited Neoplasia Alleles Syndrome in a Chilean Oncology Institute: New Combinations and Genetic Landscape. [PDF]

Genes (Basel)
Sepúlveda Bustos F, Martin Merlez F, Campos Jadrijevic D, Saavedra MP, Selman Bravo C.   +4 more
europepmc   +1 more source

Senescent Mesenchymal Stromal Cells Drive Stem Cell Aging Through Dysregulated Chemokine Synthesis

Aging Cell, Volume 25, Issue 11, November 2026.
Senescent MSCs do more than fuel inflammaging: they disrupt the chemokine signals that maintain stem cell function. We propose that restoring this signaling balance through senolytics, senomorphics, or MSC rejuvenation may preserve regenerative capacity during aging. ABSTRACT Aging is accompanied by a progressive decline in tissue regenerative capacity,
Shaianne N. Stein, Lorena R. Braid
wiley   +1 more source

Inactivation of CDKN2AARF Promotes p53-Independent Remodeling of the PDAC Tumor Microenvironment. [PDF]

Cancer Res
Ferreira S, Flowers BM, Choi WY, Farina-Morillas M, Gatto A, Bhattacharyya S, Boross G, Hassan G, Mulligan AS, Vogel H, Wood LD, Weaver VM, Winslow MM, Petrov DA, Sherman MH, Choi HY, Hayes DN, Aguirre AJ, Seoane JA, Attardi LD.   +19 more
europepmc   +1 more source

Patient‐derived surgical samples reveal the cellular and molecular signatures of glioblastoma infiltration in distinct radiological zones

Brain Pathology, Volume 36, Issue 6, November 2026.
Integrated histological and transcriptional profiling of the glioblastoma periphery reveals clinically relevant tumor infiltration beyond MRI‐defined boundaries. MRI‐guided biopsies from contrast‐enhancing (CE), non‐contrast‐enhancing (nCE), edema (E), and radiologically normal (N) regions demonstrate that nCE areas frequently retain neoplastic and ...
Olaya de Dios, Juan Romero, María de los Ángeles Ramírez‐González, Beatriz Herranz, Alicia Avis‐Bodas, Juliana Manosalva, Diego Megías, Ana Ramos, Juan Manuel Sepúlveda‐Sánchez, Ricardo Gargini, Berta Segura‐Collar, Gabriel Velilla, Bárbara Meléndez, Pedro González, Luis Jiménez‐Roldán, Guillermo García‐Posadas, Aurelio Hernández‐Laín, Ángel Pérez‐Núñez, Pilar Sánchez‐Gómez   +18 more
wiley   +1 more source