Results 171 to 180 of about 24,207 (211)
Phosphatases: An undervalued class of antitumor drug targets. [PDF]
Acta Pharm Sin BWang M, Zhan P, Song Y.
europepmc +1 more source
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Recent advances on cyclins, CDKs and CDK inhibitors
Trends in Cell Biology, 1997In eukaryotes, cell division is controlled by cyclin-dependent kinases (CDKs). Here we summarize a few new developments on the regulation of the cell cycle by CDK-cyclin complexes. We have focused on three aspects in which there has been recent progress: the structural analysis of these complexes, the phenotypes of mice carrying knockouts of CDK ...
Cristina MartÃn-Castellanos
exaly +3 more sources
Seminars in Cancer Biology, 1995
The connections between cancer and the basic machinery of the cell cycle have taken a surprisingly long time to become apparent. However, the past 2 years has seen a dramatic increase in the number of cell cycles regulators that have been implicated as either protooncogenes or as tumour suppressor genes.
Jonathon Pines
exaly +3 more sources
The connections between cancer and the basic machinery of the cell cycle have taken a surprisingly long time to become apparent. However, the past 2 years has seen a dramatic increase in the number of cell cycles regulators that have been implicated as either protooncogenes or as tumour suppressor genes.
Jonathon Pines
exaly +3 more sources
Regulation of CDKs by phosphorylation
1998The key transitions of the cell cycle are controlled via the sequential activation and inactivation of members of the cyclin-dependent kinase (CDK) subfamily of protein kinases. The activities of these enzymes are regulated by multiple mechanisms including both activating and inactivating phosphorylations, binding to regulatory subunits termed cyclins,
M J, Solomon, P, Kaldis
openaire +2 more sources
Nature, 1995
As key regulators of the cell cycle, the cyclin-dependent kinases must be tightly regulated by extra- and intracellular signals. The activity of cyclin-dependent kinases is controlled by four highly conserved biochemical mechanisms, forming a web of regulatory pathways unmatched in its elegance and intricacy.
openaire +2 more sources
As key regulators of the cell cycle, the cyclin-dependent kinases must be tightly regulated by extra- and intracellular signals. The activity of cyclin-dependent kinases is controlled by four highly conserved biochemical mechanisms, forming a web of regulatory pathways unmatched in its elegance and intricacy.
openaire +2 more sources
Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology, 2021
Xiwei Jia, Yuting Li, Ziping Zhang
exaly
Xiwei Jia, Yuting Li, Ziping Zhang
exaly