Results 181 to 190 of about 27,135 (258)

Asymptomatic Versus Symptomatic Alzheimer's Disease Neuropathology: A Systematic Review of Differences Reported in Post‐Mortem Studies

Neuropathology and Applied Neurobiology, Volume 52, Issue 3, June 2026.
Graphical summary of post‐mortem brain tissue findings that differ between symptomatic and asymptomatic AD. Current evidence suggests reduced accumulation of Aβ and p‐tau oligomers, particularly at synapses, preserved neuronal and synaptic integrity and metabolic activity and a dynamic profile of glial and immune responses in ASYMAD.
Thiago Guilherme Rêgo Barros, Laura Barbosa Grossi, Maria Letícia da Silva Campos, Israel Bem‐Hur Netto Cardoso, Antônio Lúcio Teixeira, Aline Silva de Miranda, Eliana Cristina de Brito Toscano   +6 more
wiley   +1 more source

Frontiers in Cell-Cycle-Targeting Therapies: Addressing the Heterogeneity of the Cancer Cell Cycle. [PDF]

Cancers (Basel)
Ganesan IP, Kiyokawa H.
europepmc   +1 more source

The cyclin‐dependent kinase inhibitor KIP‐RELATED PROTEIN 6 promotes stem cell death upon DNA damage in Arabidopsis roots

The Plant Journal, Volume 126, Issue 5, June 2026.
SUMMARY Maintenance of genome integrity is essential for plant growth and survival. Plants have evolved specialised DNA damage responses that coordinate DNA repair, cell cycle arrest and stem cell‐specific cell death. However, the mechanism through which damaged stem cells are selectively eliminated remains unclear.
Toshiki Wada, Ayako N. Sakamoto, Masaaki Umeda, Naoki Takahashi   +3 more
wiley   +1 more source

Noncanonical HIPPO-MST1/2 Promotes Hyperproliferation of Pulmonary Vascular Cells through CDC20. [PDF]

Am J Respir Cell Mol Biol
Dey T, Zhyvylo I, Jiang L, Olapoju SO, Pena A, Avolio T, Lin D, Goncharov D, Greenland JR, Wolters PJ, DeLisser H, Pullamsetti SS, Kudryashova TV, Goncharova EA.   +13 more
europepmc   +1 more source

Intravesical Delivery of P21 mRNA–Loaded Lipid Nanoparticles as a Tumor Suppressor Replacement Therapy for Bladder Cancer

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
Intravesical delivery of p21 mRNA‐loaded lipid nanoparticles (p21‐LNP) restores the tumor suppressor p21 in bladder cancer. Localized p21 expression directly induces cell cycle arrest, DNA damage and apoptosis, and ultimately inhibits orthotopic tumor growth with minimal systemic distribution and favorable safety.
Jie Zeng, Ziyi Cao, Chenghe Wang, Yingjie Xu   +3 more
wiley   +1 more source

The preliminary study on the effect of PSEN1 on the proliferation and invasion of breast cancer cells. [PDF]

Transl Breast Cancer Res
Yang M, Zou JQ, Yang W.
europepmc   +1 more source

Pan-cyclin-dependent kinase inhibition is a potential treatment for adenoid cystic carcinoma that downregulates the MYB::NFIB fusion and induces tumor regression. [PDF]

Cancer Commun (Lond)
Huang J, Larsson P, Kakay Afshari M, Tejera Nevado P, Tešan Tomić T, Fehr A, Jäwert F, Stenman G, Andersson MK.   +8 more
europepmc   +1 more source

Multi-analytical and biological insights into Malcolmia grandiflora Kuntze. [PDF]

Sci Rep
Elwekeel AH, Mohamed EIA, Amin E, Sadek M, Mohamed M, Hassan MHA.   +5 more
europepmc   +1 more source

SDC4 silencing promotes cell cycle arrest at the restriction point (R point) in anoikis-resistant endothelial cells. [PDF]

Cytotechnology
Ferreira BZF, Pereira DMC, Onyeisi JOS, Machado RS, Tamura RE, Nader HB, Lopes CC.   +6 more
europepmc   +1 more source

Cytoplasmic cyclin D1 modulates brain cortex development. [PDF]

Cell Mol Life Sci
Pedraza N, Rocandio D, Zammou B, Monserrat MV, Ortiz-Brugués A, Marfull-Oromí P, Chauhan D, Encinas M, Dolcet X, Ferrezuelo F, Garí E, Egea J.   +11 more
europepmc   +1 more source