Results 161 to 170 of about 50,848 (283)

Essential Oils of Argyreia capitiformis (Poir.) Ooststr. and Argyreia nasirii D.F. Austin: Chemical Analysis and Biological Activities

open access: yesChemistry &Biodiversity, Volume 23, Issue 11, November 2026.
Essential oils of Argyreia capitiformis and Argyreia nasirii display clearly distinct chemical and biological profiles. A. capitiformis is dominated by sesquiterpene hydrocarbons, particularly (E)‐caryophyllene, and shows cytotoxicity against HepG2, SK‐LU‐1, and MCF‐7 cells. In contrast, A.
Tran Thi Ngoc Hanh   +7 more
wiley   +1 more source

Ameliorative Effect of Lycopene and Capsaicinoid Glucoside in Acute Myeloid Leukemia

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 11, November 2026.
Lycopene and capsaicinoid glucoside synergistically reduce leukemia cell proliferation, restore oxidative balance, and normalize hematological parameters in benzene‐induced rat models, demonstrating potent anti‐apoptotic and cytotoxic effects in vitro and in vivo.
Somia Shehzadi   +6 more
wiley   +1 more source

CDK7, CDK9, or CDK11 inhibition reduces neutrophil-driven inflammation and tissue damage in experimental autoimmune models. [PDF]

open access: yesCell Commun Signal
Schlotfeldt M   +21 more
europepmc   +1 more source

Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives

open access: yesJSFA reports, Volume 6, Issue 11, Page 473-489, November 2026.
Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz   +10 more
wiley   +1 more source

Protein Lactylation in Cancer: From Mechanisms to Therapy

open access: yesMedComm, Volume 7, Issue 11, November 2026.
Increased glycolysis and lactate accumulation promote histone and nonhistone protein lactylation, linking tumor metabolic reprogramming to treatment adaptation. Lactylation enhances DNA repair, suppresses antitumor immunity, strengthens antioxidant defenses, and facilitates cell‐cycle checkpoint escape, collectively promoting resistance to chemotherapy,
Wentian Huang   +8 more
wiley   +1 more source

QM and QM/MM studies of the phosphoryl transfer reaction catalyzed by a cyclin-dependent kinase (CDKs)

open access: yes
The regulation of the eukaryotic cell cycle depends on the action of several related Ser/Thr protein kinases called cyclin-dependent kinases (CDKs), which are transiently activated at specific stages of the cycle, and which are also very promising ...
Roethlisberger, Ursula   +4 more
core  

Small‐Molecule Kinase Inhibitors Modulating Circadian Rhythms

open access: yesMedicinal Research Reviews, Volume 46, Issue 6, Page 1735-1752, November 2026.
ABSTRACT The circadian clock mechanism generates 24‐h rhythms crucial for regulating various physiological processes, and its dysregulation has been implicated in numerous diseases. In cells, the circadian clock operates through a transcriptional‐translational feedback loop, where phosphorylation plays a pivotal role in maintaining accurate circadian ...
Irene Castellino   +3 more
wiley   +1 more source

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