Essential oils of Argyreia capitiformis and Argyreia nasirii display clearly distinct chemical and biological profiles. A. capitiformis is dominated by sesquiterpene hydrocarbons, particularly (E)‐caryophyllene, and shows cytotoxicity against HepG2, SK‐LU‐1, and MCF‐7 cells. In contrast, A.
Tran Thi Ngoc Hanh +7 more
wiley +1 more source
Mammalian cell-cycle regulation: several Cdks, numerous cyclins and diverse compensatory mechanisms
A. Satyanarayana, P. Kaldis
semanticscholar +1 more source
Ameliorative Effect of Lycopene and Capsaicinoid Glucoside in Acute Myeloid Leukemia
Lycopene and capsaicinoid glucoside synergistically reduce leukemia cell proliferation, restore oxidative balance, and normalize hematological parameters in benzene‐induced rat models, demonstrating potent anti‐apoptotic and cytotoxic effects in vitro and in vivo.
Somia Shehzadi +6 more
wiley +1 more source
CDK7, CDK9, or CDK11 inhibition reduces neutrophil-driven inflammation and tissue damage in experimental autoimmune models. [PDF]
Schlotfeldt M +21 more
europepmc +1 more source
Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives
Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz +10 more
wiley +1 more source
Protein Lactylation in Cancer: From Mechanisms to Therapy
Increased glycolysis and lactate accumulation promote histone and nonhistone protein lactylation, linking tumor metabolic reprogramming to treatment adaptation. Lactylation enhances DNA repair, suppresses antitumor immunity, strengthens antioxidant defenses, and facilitates cell‐cycle checkpoint escape, collectively promoting resistance to chemotherapy,
Wentian Huang +8 more
wiley +1 more source
The Role of Transcriptional and Atypical Cyclin-Dependent Protein Kinases in Melanoma. [PDF]
Kaszubski J +3 more
europepmc +1 more source
The regulation of the eukaryotic cell cycle depends on the action of several related Ser/Thr protein kinases called cyclin-dependent kinases (CDKs), which are transiently activated at specific stages of the cycle, and which are also very promising ...
Roethlisberger, Ursula +4 more
core
Small‐Molecule Kinase Inhibitors Modulating Circadian Rhythms
ABSTRACT The circadian clock mechanism generates 24‐h rhythms crucial for regulating various physiological processes, and its dysregulation has been implicated in numerous diseases. In cells, the circadian clock operates through a transcriptional‐translational feedback loop, where phosphorylation plays a pivotal role in maintaining accurate circadian ...
Irene Castellino +3 more
wiley +1 more source
The Potential of Cytokinins as Innovative Components of Multifunctional Biomaterials: Mechanisms of Biological Activity and Potential in Tissue Regeneration-In Vitro Studies-Review. [PDF]
Jabłońska-Trypuć A.
europepmc +1 more source

