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Novel 1H-Indole-3-carboxamide Derivatives as CDK4 Inhibitors for Treating Cancer. [PDF]
ACS Med Chem LettSabnis RW.
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Sensitizing tumor response to topoisomerase I antibody-drug conjugate by selective CDK7 inhibition. [PDF]
Sci AdvJung H +15 more
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Recent Advances on Cyclins, CDKs and CDK Inhibitors
Trends in Cell Biology, 1997In eukaryotes, cell division is controlled by cyclin-dependent kinases (CDKs). Here we summarize a few new developments on the regulation of the cell cycle by CDK-cyclin complexes. We have focused on three aspects in which there has been recent progress: the structural analysis of these complexes, the phenotypes of mice carrying knockouts of CDK ...
Cristina Martin-Castellanos
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Seminars in Cancer Biology, 1995
The connections between cancer and the basic machinery of the cell cycle have taken a surprisingly long time to become apparent. However, the past 2 years has seen a dramatic increase in the number of cell cycles regulators that have been implicated as either protooncogenes or as tumour suppressor genes.
Jonathon Noe Joseph Pines
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The connections between cancer and the basic machinery of the cell cycle have taken a surprisingly long time to become apparent. However, the past 2 years has seen a dramatic increase in the number of cell cycles regulators that have been implicated as either protooncogenes or as tumour suppressor genes.
Jonathon Noe Joseph Pines
exaly +3 more sources
Cell Cycle, CDKs and Cancer: A Changing Paradigm
Nature Reviews Cancer, 2009Marcos Malumbres, Mariano Barbacid
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CDKS and CKIS: Molecular Targets for Tissue Remodelling
Nature Reviews Drug Discovery, 2002Elizabeth G Nabel
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