Results 241 to 250 of about 50,848 (283)
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Regulation of CDKs by phosphorylation

1998
The key transitions of the cell cycle are controlled via the sequential activation and inactivation of members of the cyclin-dependent kinase (CDK) subfamily of protein kinases. The activities of these enzymes are regulated by multiple mechanisms including both activating and inactivating phosphorylations, binding to regulatory subunits termed cyclins,
M J, Solomon, P, Kaldis
openaire   +2 more sources

Principles of CDK regulation

Nature, 1995
As key regulators of the cell cycle, the cyclin-dependent kinases must be tightly regulated by extra- and intracellular signals. The activity of cyclin-dependent kinases is controlled by four highly conserved biochemical mechanisms, forming a web of regulatory pathways unmatched in its elegance and intricacy.
openaire   +2 more sources

Cycling with CDKs

Trends in Cell Biology, 1994
L F, Lock, D, Wickramasinghe
openaire   +2 more sources

CDK inhibitors

2021
HU ZHILONG   +4 more
openaire   +3 more sources

Synthesis, biological evaluation and molecular docking studies of pyrazole derivatives coupling with a thiourea moiety as novel CDKs inhibitors.

European journal of medicinal chemistry, 2013
Jian Sun   +7 more
semanticscholar   +1 more source

The Expression Regulation of Cyclins and CDKs in Ovary via miR-9c and miR-263a of Scylla Paramamosain

Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology, 2021
Xiwei Jia, Xianyuan Zeng, Yuting Li
exaly  

TG02, a novel oral multi-kinase inhibitor of CDKs, JAK2 and FLT3 with potent anti-leukemic properties

Leukemia, 2012
Kee C. Goh   +15 more
semanticscholar   +1 more source

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