Results 41 to 50 of about 10,537 (192)

CCAAT/enhancer binding protein β is dispensable for development of lung adenocarcinoma. [PDF]

open access: yesPLoS ONE, 2015
Lung cancer is the leading cause of cancer death worldwide. Although disruption of normal proliferation and differentiation is a vital component of tumorigenesis, the mechanisms of this process in lung cancer are still unclear.
Yi Cai   +10 more
doaj   +1 more source

Differential expression of CEBPB in amyotrophic lateral sclerosis.

open access: yes, 2022
Neurodegenerative diseases that affect the motor neurons, including amyotrophic lateral sclerosis (ALS), have little treatment options and are generally rapidly fatal (1, 2).
Shahan Mamoor
core   +1 more source

DNA hypermethylation contributes to colorectal cancer metastasis by regulating the binding of CEBPB and TFCP2 to the CPEB1 promoter [PDF]

open access: yesClinical Epigenetics, 2021
Abstract Background Aberrant DNA methylation has been firmly established as a factor contributing to the pathogenesis of colorectal cancer (CRC) via its capacity to silence tumour suppressor genes. However, the methylation status of multiple tumour suppressor genes and their roles in promoting CRC metastasis are not well
Keke Shao   +10 more
openaire   +2 more sources

Non-canonical function of DPP4 promotes cognitive impairment through ERp29-associated mitochondrial calcium overload in diabetes

open access: yesiScience, 2023
Summary: DPP4 has been shown to induce diabetes-associated mitochondrial dysfunction and cognitive impairment through its non-canonical function. Here, we report that enhanced DPP4 expression in diabetes contributes to IP3R2-mediated mitochondria ...
Jiaxiu Li   +9 more
doaj   +1 more source

Tetratricopeptide repeat domain 36 deficiency mitigates renal tubular injury by inhibiting TGF-β1-induced epithelial–mesenchymal transition in a mouse model of chronic kidney disease

open access: yesGenes and Diseases, 2022
The damage of proximal tubular epithelial cells (PTECs) is considered a central event in the pathogenesis of chronic kidney disease (CKD) and deregulated repair processes of PTECs result in epithelial–mesenchymal transition (EMT), which in turn ...
Xin Yan   +6 more
doaj   +1 more source

The CCAAT/Enhancer Binding Protein Beta (cebpb) is essential for the development of enveloping layer (EVL) in zebrafish

open access: yesAquaculture and Fisheries, 2023
Epiboly, the coordinated spreading of the enveloping layer (EVL), the yolk syncytial layer (YSL) and the deep cells (DCs) toward the vegetal pole, is required for gastrulation. Interference with the EVL leads to early developmental failure.
Xin Zhang   +6 more
doaj   +1 more source

Deletion of Cebpb does not affect tumor burden in vivo.

open access: yes, 2015
(A) Scheme of the strategy generating lung specific inducible EGFR-TL transgenic mice with Cebpb knockout background. (B) Genotype of EGFRTL/CCSP-rtTA/Cebpb+/+, CCSP-rtTA/Cebpb+/+ and EGFRTL/CCSP-rtTA/Cebpb-/- mice.
Ayako Hirata (701756)   +10 more
core   +1 more source

CEBPB VEGF - Neurite Count & Length Raw Data

open access: yes, 2019
CEBPB VEGF - Neurite Count & Length Raw ...
Marc Halterman (7015238)
core   +1 more source

Transcription factor CEBPB inhibits the proliferation of osteosarcoma by regulating downstream target gene CLEC5A [PDF]

open access: yesJournal of Clinical Laboratory Analysis, 2019
AbstractObjectiveTo screen the gene related to osteosarcoma (OS) metastasis and the molecular mechanism.MethodsGEO database and R2 chip analysis platform were used to screen genes related to OS metastasis. UCSC gene browser was used to find the transcription factor (TF) of CLEC5A. The mRNA level and protein expression of CLEC5A in OS tissues and normal
Jianhua Lu   +4 more
openaire   +2 more sources

RETRACTED ARTICLE: Stress-induced epinephrine promotes epithelial-to-mesenchymal transition and stemness of CRC through the CEBPB/TRIM2/P53 axis

open access: yesJournal of Translational Medicine, 2022
Background Previous studies have indicated that chronic emotional stressors likely participate in the occurrence of cancers. However, direct evidence connecting stress and colorectal cancer development remains almost completely unexplored.
Zili Zhou   +8 more
doaj   +1 more source

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