Results 21 to 30 of about 44,501 (221)

Impact of Cefazolin Shortage on Clinical Outcomes of Adult Patients with Bacteremia Caused by Methicillin-Susceptible Staphylococcus aureus in a Tertiary Care University Hospital

Antibiotics, 2021
Cefazolin is an essential antibiotic used for treating bacteremia; in particular, it is recommended as a first-line agent for infections caused by methicillin-susceptible Staphylococcusaureus (MSSA).
Atsushi Uda, Kenichiro Onuma, Katsumi Shigemura, Koichi Kitagawa, Yonmin Yan, Kayo Osawa, Ikuko Yano, Takayuki Miyara   +7 more
doaj   +1 more source

Use of Estimating Equations for Dosing Antimicrobials in Patients with Acute Kidney Injury Not Receiving Renal Replacement Therapy. [PDF]

, 2018
Acute kidney injury (AKI) can potentially lead to the accumulation of antimicrobial drugs with significant renal clearance. Drug dosing adjustments are commonly made using the Cockcroft-Gault estimate of creatinine clearance (CLcr). The Modified Jelliffe
Awdishu, Linda, Bouchard, Josée, Chertow, Glenn M, Connor, Ana Isabel, Macedo, Etienne, Mehta, Ravindra L   +5 more
core   +2 more sources

Perioperative use of cefazolin ameliorates postoperative cognitive dysfunction but induces gut inflammation in mice

Journal of Neuroinflammation, 2018
Background Emerging evidence indicates that long-time use of multiple antibiotics can induce cognitive dysfunction via gut dysbiosis. Cefazolin is often used for 3 to 5 days to prevent perioperative infection.
Peng Liang, Weiran Shan, Zhiyi Zuo
doaj   +1 more source

Definitive Cefazolin Treatment for Community-Onset Enterobacteriaceae Bacteremia Based on the Contemporary CLSI Breakpoint: Clinical Experience of a Medical Center in Southern Taiwan

Antibiotics, 2019
Cefazolin is traditionally active against Escherichia coli, Klebsiella species, and Proteus mirabilis (EKP) isolates. The Clinical and Laboratory Standards Institute (CLSI) has twice updated cefazolin susceptibility breakpoints for EKP since 2010, but ...
Ching-Chi Lee, Chung-Hsun Lee, Po-Lin Chen, Chih-Chia Hsieh, Hung-Jen Tang, Wen-Chien Ko   +5 more
doaj   +1 more source

Current Animal Models of Postoperative Spine Infection and Potential Future Advances. [PDF]

, 2015
Implant related infection following spine surgery is a devastating complication for patients and can potentially lead to significant neurological compromise, disability, morbidity, and even mortality.
Bernthal, NM, Dworsky, EM, Hu, Y, Loftin, AH, Lord, EL, Manegold, JE, Scaduto, AA, Stavrakis, AI   +7 more
core   +1 more source

Increased Rate of Early Periprosthetic Joint Infection in Total Hip Arthroplasty With the Use of Alternatives to Cefazolin Despite Additional Gram-Negative Coverage

Arthroplasty Today, 2022
Background: Periprosthetic joint infection (PJI) remains one of the most devastating complications following total joint arthroplasty. Appropriate prophylactic antimicrobial administration and antibiotic stewardship are major factors impacting the risk ...
Dionisio Ortiz, III, MD, Greg M. Teo, MD, Katherine Lygrisse, MD, Vinay K. Aggarwal, MD, William J. Long, MD, FRCSC   +4 more
doaj   +1 more source

Cefazolin Prophylaxis for Total Joint Arthroplasty: Obese Patients Are Frequently Underdosed and at Increased Risk of Periprosthetic Joint Infection [PDF]

, 2018
Background One of the most effective prophylactic strategies against periprosthetic joint infection (PJI) is administration of perioperative antibiotics. Many orthopedic surgeons are unaware of the weight-based dosing protocol for cefazolin.
Greenky, Max R., Kheir, Michael M., Parvisi, Javad, Rondon, Alexander J., Shohat, Noam, Tan, Timothy L.   +5 more
core   +1 more source

Bioanalytical development and validation of liquid chromatographic–tandem mass spectrometric methods for the quantification of total and free cefazolin in human plasma and cord blood

Practical Laboratory Medicine, 2015
Objectives: Cefazolin is a commonly prescribed β-lactam antibiotic for prophylaxis against skin infections following surgery, including caesarean sections.
Christopher A. Crutchfield, Mark A. Marzinke   +1 more
doaj   +1 more source

Preoperative administration of cephalosporins for elective caesarean delivery [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2010
Introduction. Antibiotic prophylaxis means administration of antibiotics in prevention of infections. Objective. To investigate the efficacy of a single dose preoperative administration of ceftriaxone and cefazolin in the prevention of intra- and ...
Bogavac Mirjana, Grujić Ilija, Grujić Zorica, Popović Jovan   +3 more
doaj   +1 more source

A rare case of clostridium difficile infection-associated reactive arthritis [PDF]

, 2018
Clostridium difficile is an uncommon cause of reactive arthritis in children. We herein present a rare case of C. difficile infection-associated reactive arthritis (CDIAReA) in a child, who developed severe diarrhea and a knee effusion following a course
Derinkuyu, B.E., Polat, Meltem, Tapısız, A., Tezer, H.   +3 more
core   +1 more source