Results 51 to 60 of about 47,590 (163)

Risk of Acute Kidney Injury Associated With Nephrotoxic Burden in Hospitalized Patients: A Scoping Review

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 891-904, April 2026.
Limited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations)
Wafa Alatawi   +6 more
wiley   +1 more source

The Evaluation of Machine Learning Models Using Matrix‐Assisted Laser Desorption/Ionization Time‐of‐Flight Mass Spectrometry (MALDI–TOF–MS) Spectra for the Prediction of Antibiotic Resistance in Klebsiella pneumoniae

open access: yesMicrobiologyOpen, Volume 15, Issue 2, April 2026.
Machine learning models developed from matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry spectra can rapidly predict antimicrobial resistance in Klebsiella pneumoniae. By transforming routine spectral data into accurate resistance profiles within minutes, this approach could reduce diagnostic delays and support earlier ...
Stephen Mark Edward Fordham
wiley   +1 more source

Dual delivery of active antibactericidal agents and bone morphogenetic protein at sustainable high concentrations using biodegradable sheath-core-structured drug-eluting nanofibers

open access: yesInternational Journal of Nanomedicine, 2016
Yung-Hen Hsu,1,2 Chang-Tun Lin,2 Yi-Hsun Yu,1,2 Ying-Chao Chou,1,2 Shih-Jung Liu,1,2 Err-Cheng Chan3 1Department of Orthopedic Surgery, Chang Gung Memorial Hospital, 2Department of Mechanical Engineering, 3Department of Medical Biotechnology and ...
Hsu YH   +5 more
doaj  

Endogenous endophthalmitis secondary to subclinical pyelonephritis

open access: yes
Journal of Hospital Medicine, EarlyView.
Riya N. Soni   +2 more
wiley   +1 more source

Emerging Antimicrobial Resistance in Klebsiella pneumoniae: A Molecular and Antibiogram Insight From the Beef Value Chain in Bangladesh

open access: yesMicrobiologyOpen, Volume 15, Issue 2, April 2026.
A total of 132 Multidrug‐resistant Klebsiella pneumoniae was detected across the beef value chain in Bangladesh, including slaughterhouses, wet markets, and ready‐to‐eat beef outlets. Upon cultural traits, PCR, 16S rRNA sequencing, antibiogram analysis, and ARG detection revealed carbapenem resistance genes (blaIMP and blaBIC), highlighting foodborne ...
Md Sodor Uddin   +11 more
wiley   +1 more source

Farm‐Level Factors Associated With Multidrug‐Resistant Escherichia coli and Klebsiella spp. in Bulk Tank Milk in Tigray, Northern Ethiopia

open access: yesMicrobiologyOpen, Volume 15, Issue 2, April 2026.
This cross‐sectional study identified farm‐level factors associated with multidrug‐resistant (MDR) Escherichia coli and Klebsiella spp. in bulk tank milk in Tigray, Northern Ethiopia, emphasizing the role of antimicrobial use practices and hygiene management in MDR occurrence within dairy production systems.
Goyitom Gebremedhn Gebru   +2 more
wiley   +1 more source

Neonatal melioidosis case reports—Lessons learned

open access: yesClinical Case Reports, 2020
In endemic regions, include melioidosis in the routine differential diagnosis of neonates with respiratory distress, and consider early empirical ceftazidime treatment for neonates with worsening respiratory distress.
Sylvia Daim   +6 more
doaj   +1 more source

From Synthesis to Therapeutics: Bioactive‐Coated Zein Nanoparticles in Drug Delivery

open access: yesBiopolymers, Volume 117, Issue 2, March 2026.
ABSTRACT Polymeric zein nanoparticles (ZNP), derived from corn protein, are biodegradable drug carriers with high stability and low synthesis costs. Their amphiphilic nature allows efficient encapsulation of both hydrophilic and lipophilic drugs, making them promising for drug delivery.
Milena Ferreira de Lima   +8 more
wiley   +1 more source

Unraveling the Complexities of Kartagener's Syndrome: A Case of Bronchiectasis, Isolated Dextrocardia, and Primary Ciliary Dyskinesia in an Adult With Chronic Respiratory Symptoms

open access: yesClinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Kartagener's Syndrome (KS), a rare autosomal recessive disorder and a subset of Primary Ciliary Dyskinesia (PCD), is characterized by chronic sinusitis, bronchiectasis, and, in approximately 50% of cases, situs inversus. This condition arises from genetic mutations that impair motile cilia function, leading to defective mucociliary clearance ...
Ibrahim Khalil   +3 more
wiley   +1 more source

Polymicrobial Pasteurella multocida‐Anaerobic Coinfection Followhing a Cat Bite: Limb Salvage Through Metagenomic Next‐Generation Sequencing‐Guided Diagnosis and Multidisciplinary Management

open access: yesClinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Successful management of a Pasteurella multocida and polymicrobial infection following a cat bite on the left leg entailed debridement, split‐thickness skin grafting with vacuum‐sealing drainage, and targeted antibiotic treatment. This approach enabled successful incorporation of the skin graft, preserving the limb and eliminating the ...
Yuanqing Qu   +4 more
wiley   +1 more source

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