Results 11 to 20 of about 66,137 (309)

Safety of celecoxib versus traditional nonsteroidal anti-inflammatory drugs in older patients with arthritis

open access: yesJournal of Pain Research, 2018
Sooyoung Shin1,2 1Department of Clinical Pharmacy, College of Pharmacy, Ajou University, Yeongtong-gu, Suwon, Republic of Korea; 2Research Institute of Pharmaceutical Science and Technology (RIPST), Ajou University, Yeongtong-gu, Suwon, Republic of Korea
Shin S
doaj   +2 more sources

Celecoxib for Mood Disorders: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

open access: yesJournal of Clinical Medicine, 2023
The effects of celecoxib on a broad spectrum of mood disorders and on inflammatory parameters have not yet been comprehensively evaluated. The aim of this study was to systematically summarize the available knowledge on this topic.
Adam Gędek   +4 more
semanticscholar   +1 more source

Celecoxib for osteoarthritis [PDF]

open access: yesCochrane Database of Systematic Reviews, 2017
Osteoarthritis (OA) is the most common form of arthritis and is caused by degeneration of the joint cartilage and growth of new bone, cartilage and connective tissue. It is often associated with major disability and impaired quality of life. There is currently no consensus on the best treatment to improve OA symptoms.
Livia Puljak   +5 more
openaire   +3 more sources

Effect of Celecoxib vs Placebo Added to Standard Adjuvant Therapy on Disease-Free Survival Among Patients With Stage III Colon Cancer: The CALGB/SWOG 80702 (Alliance) Randomized Clinical Trial.

open access: yesJournal of the American Medical Association (JAMA), 2021
Importance Aspirin and cyclooxygenase 2 (COX-2) inhibitors have been associated with a reduced risk of colorectal polyps and cancer in observational and randomized studies.
J. Meyerhardt   +21 more
semanticscholar   +1 more source

Effect of Cyclooxygenase-2 Inhibitors in Double J Stent Removal under Local Anesthesia

open access: yesThe Annals of African Surgery, 2021
Introduction: Celecoxib is a selective cyclooxygenase-2(COX-2) inhibitor that can reduce the inflammatory process during double J (DJ) stent removal procedure.
Rulianov Rulianov   +3 more
doaj   +1 more source

Topical Nano-Vesicular Spanlastics of Celecoxib: Enhanced Anti-Inflammatory Effect and Down-Regulation of TNF-α, NF-кB and COX-2 in Complete Freund’s Adjuvant-Induced Arthritis Model in Rats

open access: yesInternational Journal of Nanomedicine, 2021
Background Rheumatoid arthritis (RA) is an autoimmune disease that underlies chronic inflammation of the synovial membrane. Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used to treat RA.
Eman Alaaeldin   +5 more
semanticscholar   +1 more source

PGE2/EP4 skeleton interoception activity reduces vertebral endplate porosity and spinal pain with low-dose celecoxib

open access: yesBone Research, 2021
Skeletal interoception regulates bone homeostasis through the prostaglandin E2 (PGE2) concentration in bone. Vertebral endplates undergo ossification and become highly porous during intervertebral disc degeneration and aging.
Peng Xue   +10 more
semanticscholar   +1 more source

Effect of Celecoxib vs Placebo as Adjuvant Therapy on Disease-Free Survival Among Patients With Breast Cancer: The REACT Randomized Clinical Trial.

open access: yesJAMA Oncology, 2021
Importance Patients with breast cancer remain at risk of relapse after adjuvant therapy. Celecoxib has shown antitumor effects in preclinical models of human breast cancer, but clinical evidence is lacking.
R. C. Coombes   +24 more
semanticscholar   +1 more source

Inhibition mechanism of the intracellular transporter Ca2+-pump from sarco-endoplasmic reticulum by the antitumor agent dimethyl-celecoxib. [PDF]

open access: yesPLoS ONE, 2014
Dimethyl-celecoxib is a celecoxib analog that lacks the capacity as cyclo-oxygenase-2 inhibitor and therefore the life-threatening effects but retains the antineoplastic properties. The action mechanism at the molecular level is unclear.
Ramón Coca   +4 more
doaj   +1 more source

Cardiovascular safety of celecoxib in rheumatoid arthritis and osteoarthritis patients: A systematic review and meta-analysis

open access: yesPLoS ONE, 2021
Objective To assess the cardiovascular safety of celecoxib compared to non-selective non-steroid anti-inflammatory drugs or placebo. Methods We included randomized controlled trials of oral celecoxib compared with a non-selective NSAID or placebo in ...
Bai-Ru Cheng   +9 more
semanticscholar   +1 more source

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