Results 11 to 20 of about 66,137 (309)
Sooyoung Shin1,2 1Department of Clinical Pharmacy, College of Pharmacy, Ajou University, Yeongtong-gu, Suwon, Republic of Korea; 2Research Institute of Pharmaceutical Science and Technology (RIPST), Ajou University, Yeongtong-gu, Suwon, Republic of Korea
Shin S
doaj +2 more sources
Celecoxib for Mood Disorders: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
The effects of celecoxib on a broad spectrum of mood disorders and on inflammatory parameters have not yet been comprehensively evaluated. The aim of this study was to systematically summarize the available knowledge on this topic.
Adam Gędek+4 more
semanticscholar +1 more source
Celecoxib for osteoarthritis [PDF]
Osteoarthritis (OA) is the most common form of arthritis and is caused by degeneration of the joint cartilage and growth of new bone, cartilage and connective tissue. It is often associated with major disability and impaired quality of life. There is currently no consensus on the best treatment to improve OA symptoms.
Livia Puljak+5 more
openaire +3 more sources
Importance Aspirin and cyclooxygenase 2 (COX-2) inhibitors have been associated with a reduced risk of colorectal polyps and cancer in observational and randomized studies.
J. Meyerhardt+21 more
semanticscholar +1 more source
Effect of Cyclooxygenase-2 Inhibitors in Double J Stent Removal under Local Anesthesia
Introduction: Celecoxib is a selective cyclooxygenase-2(COX-2) inhibitor that can reduce the inflammatory process during double J (DJ) stent removal procedure.
Rulianov Rulianov+3 more
doaj +1 more source
Background Rheumatoid arthritis (RA) is an autoimmune disease that underlies chronic inflammation of the synovial membrane. Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used to treat RA.
Eman Alaaeldin+5 more
semanticscholar +1 more source
Skeletal interoception regulates bone homeostasis through the prostaglandin E2 (PGE2) concentration in bone. Vertebral endplates undergo ossification and become highly porous during intervertebral disc degeneration and aging.
Peng Xue+10 more
semanticscholar +1 more source
Importance Patients with breast cancer remain at risk of relapse after adjuvant therapy. Celecoxib has shown antitumor effects in preclinical models of human breast cancer, but clinical evidence is lacking.
R. C. Coombes+24 more
semanticscholar +1 more source
Inhibition mechanism of the intracellular transporter Ca2+-pump from sarco-endoplasmic reticulum by the antitumor agent dimethyl-celecoxib. [PDF]
Dimethyl-celecoxib is a celecoxib analog that lacks the capacity as cyclo-oxygenase-2 inhibitor and therefore the life-threatening effects but retains the antineoplastic properties. The action mechanism at the molecular level is unclear.
Ramón Coca+4 more
doaj +1 more source
Objective To assess the cardiovascular safety of celecoxib compared to non-selective non-steroid anti-inflammatory drugs or placebo. Methods We included randomized controlled trials of oral celecoxib compared with a non-selective NSAID or placebo in ...
Bai-Ru Cheng+9 more
semanticscholar +1 more source