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Increased awareness of the high prevalence of celiac disease and the degree of underdiagnosis has led to calls for routine screening in certain groups. The potential consequences of underdiagnosis have been the subject of several studies. Where there is a delay in diagnosis, there may be an increased risk of associated autoimmune diseases ...
King, A L, Ciclitira, P J
openaire +6 more sources
Small-intestinal TG2-specific plasma cells at different stages of coeliac disease
Background In coeliac disease, ingestion of gluten induces the production of transglutaminase 2 (TG2)-targeted autoantibodies by TG2-specific plasma cells present at high frequency in the small intestinal mucosa in untreated disease.
Minna Hietikko +9 more
doaj +1 more source
Histopathological Assessment of Celiac Disease
Celiac Disease (CD) is an immune-mediated inflammatory disorder of the small intestine, affecting genetically susceptible individuals when exposed to gluten.
Monica, Melissa +14 more
core +1 more source
Innate Lymphoid Cells and Celiac Disease: Current PerspectiveSummary
Celiac disease (CD) is a common autoimmune disorder triggered by the ingestion of gluten in genetically susceptible individuals. Although the mechanisms underlying gliadin-mediated activation of adaptive immunity in CD have been well-characterized ...
Xuechen Yu +3 more
doaj +1 more source
The gluten-free diet (GFD) is a restrictive diet. In many cases, it must be permanent and strict, and it may be associated with both nutritional deficiencies and excesses, which can be prevented by following a healthy, natural Mediterranean GFD (Med-GFD).
Alice Scricciolo +11 more
doaj +1 more source
Secretion of celiac disease autoantibodies after in vitro gliadin challenge is dependent on small-bowel mucosal transglutaminase 2-specific IgA deposits [PDF]
Background: In celiac disease gluten, the disease-inducing toxic component in wheat, induces the secretion of autoantibodies which are targeted against transglutaminase 2 (TG2). These autoantibodies are produced in the small-intestinal mucosa, where they
Markku Maki +31 more
core +1 more source
Advances in Celiac Disease [PDF]
The incidence of gluten-related disorders (GRDs) continues to increase and its global prevalence is estimated affect to 5% of the population. s. Celiac disease (CD), Dermatitis Herpetiformis (DH), Gluten Ataxia (GA), wheat allergy (WA), and Non-Celiac ...
core +1 more source
Presence of gastrointestinal symptoms in IgA nephropathy: a cross-sectional study
Background Gastrointestinal (GI) symptoms are common in end-stage kidney disease. Mounting evidence indicates that the intestine plays an important role in the pathogenesis of IgA nephropathy (IgAN).
Jussi T. Pohjonen +7 more
doaj +1 more source
PurposeWe evaluated adherence to a gluten-free diet and associated factors in adult celiac disease patients diagnosed in childhood.MethodsComprehensive medical data on 955 pediatric celiac disease patients was collected and study questionnaires sent to ...
Laura Kivelä +12 more
doaj +1 more source
Trends in gluten research and its relationship to autoimmune and allergic diseases
Introduction: Gluten is a protein found in certain grains, and causes an autoimmune response in celiac disease patients. Although the subject of considerable research, gluten research foci and future directions are largely unknown.
Edward J. Ciaccio +3 more
doaj +1 more source

