Results 21 to 30 of about 10,389,331 (239)
Кардиоваскулярная терапия и профилактика, 2022 The search for early disease markers and the development of diagnostic systems has recently been expanding within genomics. Genomic deoxyribonucleic acid (DNA), cell-free DNA (cfDNA) and microbiome DNA obtained from different types of samples (tissues ...
V. A. Kondratskaya +6 more
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Evaluating the efficacy of DNA repair biomarkers to assess human cell response to chemotherapy using imaging flow cytometry [PDF]
, 2013 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Chemotherapy and radiotherapy are widely accepted as common forms of treatment for cancers. The majority of cancer patients receive chemotherapy alone or in
Zahir, Sheba Adam
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Frontiers in Oncology, 2018 BackgroundCell-free DNA (cfDNA) can be detected in the circulation of healthy individuals, but is found in higher concentrations in cancer patients. Furthermore, mutations in tumor cells can be identified in circulating DNA fragments.
Jonathan M. Fussey +9 more
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Novel Epigenetic Biomarkers in Pregnancy-Related Disorders and Cancers
Cells, 2019 As the majority of cancers and gestational diseases are prognostically stage- and grade-dependent, the ultimate goal of ongoing studies in precision medicine is to provide early and timely diagnosis of such disorders.
Valentina Karin-Kujundzic +8 more
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Whole genome deep sequencing analysis of cell-free DNA in samples with low tumour content
BMC Cancer, 2022 Background Circulating cell-free DNA (cfDNA) in the plasma of cancer patients contains cell-free tumour DNA (ctDNA) derived from tumour cells and it has been widely recognized as a non-invasive source of tumour DNA for diagnosis and prognosis of cancer ...
Devika Ganesamoorthy +9 more
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Endogenous cell-free DNA in fetal bovine serum introduces artifacts to in vitro cell-free DNA models
BioTechniques, 2022 Cell-free DNA (cfDNA) is of growing clinical and research significance. In vitro cfDNA models are a useful tool in cfDNA research; however, artifacts in these models may have implications for the interpretation of new and published data.
Bonnita Werner +2 more
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Balkan Medical Journal, 2020 Background: Cell-free DNA, which may be considered as “liquid” biopsy, may serve as a diagnostic and prognostic marker not only in hematological malignancies but in solid tumors as well.
Zeynep Arzu Yegin +6 more
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Comparison of methods for the isolation of cell-free DNA from cell culture supernatant
Tumor Biology, 2020 In vitro characterization of cell-free DNA using two-dimensional cell culture models is emerging as an important step toward an improved understanding of the physical and biological characteristics of cell-free DNA in human biology.
Abel Jacobus Bronkhorst +2 more
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Study the Role of Cell Free DNA in the Diagnosis of Hepatocellular Carcinoma, an Egyptian Study
Asian Pacific Journal of Cancer Biology, 2022 Background and objective: Hepatocellular carcinoma (HCC) is a primary malignancy of the liver. Since the conventional tissue biopsy and AFP have limited value, a new promising diagnostic method” liquid biopsy” has emerged.
Noha Hassan Radwan +3 more
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Circulating biomarkers to monitor cancer progression and treatment
Computational and Structural Biotechnology Journal, 2016 Tumor heterogeneity is a major challenge and the root cause of resistance to treatment. Still, the standard diagnostic approach relies on the analysis of a single tumor sample from a local or metastatic site that is obtained at a given time point. Due to
Suthee Rapisuwon +2 more
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