Results 181 to 190 of about 1,318,238 (218)

Profiling of human and microbial cell-free DNA reflects early host-pathogen interactions in sepsis. [PDF]

Front Immunol
Hoeter K, Neuberger EWI, Marriott L, De Falco A, Wiemann S, Schäfer MKE, Simon P, Kersaudy-Kerhoas M, Bodenstein M.   +8 more
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Expanding role of cell-free DNA for the early diagnosis and monitoring of pulmonary diseases. [PDF]

Chin Med J (Engl)
Yang L, Gu Y, Shao J, Zhang L, Wang C.
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Accurate and reliable detection of clonal hematopoiesis in plasma cell-free DNA. [PDF]

Blood Adv
Parker AC, Van Amburg JC, Pershad Y, Ong DA, Hoey KJ, Farady CJ, Rauch PJ, Mendelson MM, Heimlich JB, Ferrell PB, Bick AG.   +10 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Cell-Free DNA Hypermethylation in Patients with Acute Pancreatitis. [PDF]

Int J Mol Sci
Al-Mashat H, Baddoo DR, Lundbye-Christensen S, Madsen PH, Pedersen IS, Krarup HB, Stubbe BE, Thorlacius-Ussing O, Henriksen SD.   +8 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Mindful diagnostics in culture-negative endocarditis: early noninvasive diagnosis of <i>Tropheryma whipplei</i> by plasma microbial cell-free DNA. [PDF]

Antimicrob Steward Healthc Epidemiol
Jain A, Khalil S, Sohail MR, Lelenwa LC, Garcia-Sayan E, Liao KK, Hamdi A, Lasco T, Al Mohajer M.   +8 more
europepmc   +1 more source