Results 171 to 180 of about 1,318,238 (218)

Cell-free DNA in female infertility: from pathological mechanisms to clinical biomarkers. [PDF]

J Ovarian Res
Lin L, Zhang X, Liu S, Ge H.
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Analysis of morphological, morphokinetics, cell-free DNA, microRNAs parameters to predict aneuploidy status of embryos. [PDF]

PLoS One
Harzif AK, Permatasari II, Kurniawan PA, Elsiyana TA, Charilda FE, Andyra AF, Mutia HD, Ummah N, Nurbaeti P, Shadrina A, Iffanolida PA, Mutia K, Febri RR, Werdhani RA, Suryandari DA, Jatmiko W, Boediono A, Bayuaji H, Natadisastra RM, Wiweko B.   +19 more
europepmc   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Preoperative cell-free DNA concentration in plasma as a diagnostic and prognostic biomarker of clear cell renal cell carcinoma

Contemporary Oncology
Tomasz Milecki, Katarzyna Kluzek, Natalia Pstrąg, Andrzej Antczak, Wojciech Cieślikowski, Mateusz Wichtowski, Łukasz Kuncman, Zbigniew Kwias, Joanna Wesoły   +8 more
doaj   +1 more source

Systematic Review of Methods for Measuring Circulating Cell-Free DNA in Plasma of Healthy Individuals. [PDF]

Diagnostics (Basel)
Das A, Gocaj I, Yurovsky A.
europepmc   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Multimodal analysis of cell-free DNA to improve early detection of gastric cancer. [PDF]

BMC Cancer
Long VD, Huynh LAK, Vo DH, Nguyen THH, Van TTV, Nguyen GTH, Doan TN, Nguyen VH, Tran QD, Dang QT, Nguyen VTA, Ho LMQ, Ha TPD, Dang TND, Nguyen PTN, Nguyen KT, Ho VC, Le TL, Nguyen THN, Tu NH, Tran TS, Jasmine TX, Vo TL, Nai THT, Tran TT, Truong MH, Tran NC, Nguyen TC, Nguyen TT, Le BT, Tang VP, Nguyen TT, Nguyen AT, Vu HG, Van Phan T, Nguyen TNT, Cao HA, Nguyen TH, Tu LN, Giang H, Phan MD, Nguyen HN, Nguyen VTC, Tran LS.   +43 more
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source