Results 11 to 20 of about 1,646,961 (327)

Regulatory insights on gene therapies, adeno-associated virus-based gene therapies, cell/tissue-based products, and medical care/practice in cell and gene therapies: Report from the 7th Asia partnership conference - April 25, 2024

Regenerative Therapy
The 7th Asia Partnership Conference of Regenerative Medicine (APACRM) was held both in person and online on April 25, 2024, to promote the regulatory harmonization of regenerative medicine products across Asia. Recognizing domestic regulatory guidelines and their underlying rationales within each country and region is an important initial step toward ...
Yoshie Tsurumaki, Yusuke Kagawa, Shigeaki Hayashi, Hirokuni Mizoguchi, Masaaki Miyano, Masaki Fujii, Ruriko Shinozaki, Srinivasan N. Kellathur, Alex J. Zhang, Kunihiko Suzuki, Masayuki Nomura   +10 more
openaire   +4 more sources

Cardiac tissue engineering and regeneration using cell-based therapy

Stem Cells and Cloning: Advances and Applications, 2015
Mohammad T Alrefai,1–3 Divya Murali,4 Arghya Paul,4 Khalid M Ridwan,1,2 John M Connell,1,2 Dominique Shum-Tim1,2 1Division of Cardiac Surgery, 2Division of Surgical Research, McGill University Health Center, Montreal, QC, Canada; 3King Faisal ...
Alrefai MT, Murali D, Paul A, Ridwan KM, Connell JM, Shum-Tim D   +5 more
doaj   +3 more sources

Experimental orthotopic implantation of tissue-engineered tracheal graft created based on devitalized scaffold seeded with mesenchymal and epithelial cells

Вестник трансплантологии и искусственных органов, 2020
Objective: to study the viability of a tissue-engineered graft (TEG) based on a devitalized tracheal scaffold (DTS) seeded with mesenchymal stromal and epithelial cells in an experiment on rabbits with assessment of cytocompatibility and biocompatibility
M. V. Balyasin, D. S. Baranovsky, A. G. Demchenko, A. L. Fayzullin, O. A. Krasilnikova, I. D. Klabukov, M. E. Krasheninnikov, A. V. Lyundup, V. D. Parshin   +8 more
doaj   +1 more source

Rapid, ultra low coverage copy number profiling of cell-free DNA as a precision oncology screening strategy. [PDF]

, 2017
Current cell-free DNA (cfDNA) next generation sequencing (NGS) precision oncology workflows are typically limited to targeted and/or disease-specific applications.
Alva, Ajjai S, Brockman, Scott, Chinnaiyan, Arul M, Chugh, Rashmi, Feng, Felix Y, Grasso, Catherine S, Gursky, Amy, Haakenson, Christine, Henderson, James, Herman, Kirk, Hovelson, Daniel H, Husain, Hatim, Hussain, Maha H, Kamberov, Emmanuel, Kandarpa, Malathi, Kang, Qing, Krauss, John C, Langmore, John, Liu, Chia-Jen, Lonigro, Robert J, Mills, Ryan E, Morgan, Todd M, Quist, Michael J, Ramnath, Nithya, Robinson, Dan, Smith, David C, Talpaz, Moshe, Tesmer, Tim, Tewari, Muneesh, Tomlins, Scott A, Tuck, Missy, Wang, Yugang   +31 more
core   +1 more source

Blastic plasmacytoid dendritic cell neoplasm: Genomics mark epigenetic dysregulation as a primary therapeutic target [PDF]

, 2019
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive hematologic malignancy for which there is still no effective B therapy.
Abate F., Agostinelli C., Amente S., Berti E., Bertolini F., Brundu F., Cerroni L., Dellino G. I., Etebari M., Facchetti F., Falini B., Fuligni F., Indio V., Laginestra M. A., Melle F., Motta G., Orecchioni S., Paulli M., Piccioni R., Pileri A., Pileri S. A., Pimpinelli N., Rabadan R., Rossi M., Sabattini E., Sapienza M. R., Tabanelli V., Talarico G., Tarantino G., Tripodo C., Truni M.   +30 more
core   +2 more sources

The role of ultrasound-driven microbubble dynamics in drug delivery : from microbubble fundamentals to clinical translation [PDF]

, 2019
In the last couple of decades, ultrasound-driven microbubbles have proven excellent candidates for local drug delivery applications. Besides being useful drug carriers, microbubbles have demonstrated the ability to enhance cell and tissue permeability ...
De Smedt, Stefaan, Deprez, Joke, Lajoinie, Guillaume, Lentacker, Ine, Roovers, Silke, Segers, Tim, Versluis, Michel   +6 more
core   +7 more sources

Transcriptomic comparisons between cultured human adipose tissue-derived pericytes and mesenchymal stromal cells

Genomics Data, 2016
Mesenchymal stromal cells (MSCs), sometimes called mesenchymal stem cells, are cultured cells able to give rise to mature mesenchymal cells such as adipocytes, osteoblasts, and chondrocytes, and to secrete a wide range of trophic and immunomodulatory ...
Lindolfo da Silva Meirelles, Tathiane Maistro Malta, Rodrigo Alexandre Panepucci, Wilson Araújo da Silva, Jr.   +3 more
doaj   +1 more source

New perspectives to repair a broken heart [PDF]

, 2009
The aim of cardiac cell therapy is to restore at least in part the functionality of the diseased or injured myocardium by the use of stem/ progenitor cells.
BARILE, Lucio, CHIMENTI, ISOTTA, DI CONSIGLIO, ALBERTO, FORTE, ELVIRA, FRATI, GIACOMO, GAETANI, ROBERTO, GIACOMELLO, Alessandro, IONTA, VITTORIA, MESSINA, ELISA, MIRALDI, Fabio   +9 more
core   +1 more source

Tissue engineering perspectives in dentistry: review of the literature

RGO: Revista Gaúcha de Odontologia, 2018
Tooth losses due to pathological processes continue to be a reality in daily clinical dentistry, inducing functional and psychological complications in patients.
Juliana da Silva MORO, Raquel Cristine Silva BARCELOS , Thiago Gomes TERRA, Cristiane Cademartori DANESI   +3 more
doaj   +1 more source

Does mesenchymal stem cell improve the liver regeneration after the 70% hepatectomy? [PDF]

Acta Cirúrgica Brasileira, 2017
Purpose: To evaluate the effects of mesenchymal stem cells on liver regeneration in rats following a 70% hepatectomy. Methods: Forty rats were subjected to 70% hepatectomy and then ~106 mesenchymal stem cells (test group), or saline solution (control ...
Ana Karina Soares Alves, Valéria Lanzoni, Rogério Aoki Fuziy, Rita Maria Aparecida Monteiro Moura Franco, Carlos Toshinori Maeda, Gaspar de Jesus Lopes Filho, Marcelo Moura Linhares   +6 more
doaj   +1 more source