Results 1 to 10 of about 4,730,676 (232)
Antigen and Cell-Based Assays for the Detection of Non-HLA Antibodies. [PDF]
Front Immunol, 2022 To date, human leukocyte antigens (HLA) have been the major focus in the approach to acute and chronic antibody-mediated rejection (AMBR) in solid-organ transplantation.
Lammerts RGM +5 more
europepmc +2 more sources
Direct and Indirect Antioxidant Effects of Selected Plant Phenolics in Cell-Based Assays. [PDF]
Molecules, 2021 Background: Oxidative stress is a key factor in the pathophysiology of many diseases. This study aimed to verify the antioxidant activity of selected plant phenolics in cell-based assays and determine their direct or indirect effects.
Treml J +3 more
europepmc +2 more sources
Cell-Based Assays for Screening Androgen Receptor Ligands [PDF]
Seminars in Reproductive Medicine, 2015 The androgen receptor (AR, NR3C4) mediates the majority of androgen effects on target cells. The AR is activated following ligand binding that result is enhanced of target gene transcription. Several cell-based model systems have been developed that allow sensitive detection and monitoring of steroids or other compounds with AR bioactivity.
Campana C, PEZZI, Vincenzo, Rainey WE
openaire +4 more sources
Cell-based assays to identify novel retinoprotective agents. [PDF]
MethodsX, 2020 Degeneration of the retina can lead ultimately to devastating irreversible vision loss, such as in inherited retinitis pigmentosa and age-related macular degeneration. Currently there is no cure to prevent retinal degeneration. Quantitative cell-based assays can be used to test potential drugs that prevent the death of retinal cells.
Bullock J, Pagan-Mercado G, Becerra SP.
europepmc +4 more sources
Polystyrene Topography Sticker Array for Cell-Based Assays. [PDF]
Recent Prog Mater, 2020 Cells can respond to different topographical cues in their natural microenvironment. Hence, scientists have employed microfabrication techniques and materials to generate culture substrates containing topographies for cell-based assays. However, one of the limitations of custom topographical platforms is the lack of adoption by the broad research ...
Rosado-Galindo H, Domenech M.
europepmc +3 more sources
Journal of Dental Sciences, 2022 Background/purpose: Cordycepin has been proposed anti-cancer effects, however, it is unclear whether and how cordycepin affects oral squamous carcinoma cell (OSCC) migration and invasion.
Thunwa Binlateh +6 more
doaj +1 more source
STAR Protocols, 2023 Summary: Connexins (Cxs) play a crucial role in maintaining lens transparency. Here, we present a protocol for altering Cx hemichannel (HC) function in primary chicken lens fiber cells using high-titer retroviral replication competent avian sarcoma ...
Yu Du +6 more
doaj +1 more source
STAR Protocols, 2021 Summary: This protocol enables the testing of drugs against infection of epithelial cells with SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2), using pseudo-typed replication deficient vesicular stomatitis virus particles (pp-VSV) presenting
Katrin Anne Becker +5 more
doaj +1 more source
Protocol for assessing ex vivo lipolysis of murine adipose tissue
STAR Protocols, 2022 Summary: Here, we provide a detailed protocol for assessing ex vivo lipolysis of subcutaneous and visceral white adipose tissue. We describe a robust approach to detect depot-specific changes in lipolytic potential under basal and beta-adrenergic ...
Debasish Roy +2 more
doaj +1 more source
SLAS technology, 2021 Conventional cell-counting software uses contour or watershed segmentations and focuses on identifying two-dimensional (2D) cells attached on the bottom of plastic plates.
Eun Ji Jeong +2 more
semanticscholar +1 more source