, 2022 S.243-250Dynamic properties of cancer cells, most notably their ability to migrate, have been correlated successfully with their invasive nature in vivo. To establish a stronger experimental basis for such a correlation we subjected five different cancer
Kohidai, László +2 more
core +1 more source
Cell-based assays for screening: A practical workshop
, 2022 S.70This workshop, organised by European Pharmaceutical Review, took place on 9-11 December 2014 at Fraunhofer-IME SP in Hamburg, Germany and had support from Biolog, Tecan and PerkinElmer.20Nr.
Gul, S.
core +1 more source
Stochastic mathematical models of cell proliferation assays [PDF]
, 2017 Cell proliferation assays are routinely used to study collective cell behaviour, and can be interpreted with mathematical models. In this thesis, we apply a computational Bayesian technique to calibrate stochastic discrete mathematical models of cell ...
Browning, Alexander P.
core +1 more source
Protocol for imaging proteins associated with Legionella-containing vacuoles in host cells
STAR Protocols, 2021 Summary: The intracellular bacterial pathogen Legionella pneumophila exploits host cellular systems using approximately 300 effector proteins to establish a replicative niche known as the Legionella-containing vacuole (LCV).
Tomoe Kitao +3 more
doaj +1 more source
Pseudotype-based neutralization assays for influenza: a systematic analysis [PDF]
, 2015 The use of vaccination against the influenza virus remains the most effective method of mitigating the significant morbidity and mortality caused by this virus.
Ferrara, Francesca +11 more
core +1 more source
Configurable and Up-Scalable Microfluidic Life Science Platform for Cell Based Assays by Gravity Driven Sequential Perfusion and Diffusion [PDF]
, 2010 Microfluidics has the potential to significantly change the way modern biology is performed, but for this potential to be realized several on-chip integration and operation challenges have to be addressed.
Dimov, Ivan Krastev
core +2 more sources
Titration and neutralizing antibody quantification by focus forming assay for Powassan virus
STAR Protocols, 2022 Summary: The development of high-throughput assays measuring Powassan virus (POWV) lineage I and II represents an important step in virological and immunological studies.
E. Taylor Stone +4 more
doaj +1 more source
Fluorescence-based protocol for revealing cellular arrangement in biofilms
STAR Protocols, 2023 Summary: Standardized assays have greatly advanced the understanding of multicellular bacterial biofilms, but they lack cell-scale detail. Here, we present a fluorescence-based protocol that builds on past assays to reveal the cellular-scale arrangement ...
Devina Puri, Xin Fang, Kyle R. Allison
doaj +1 more source
Chemotaxis: a feedback-based computational model robustly predicts multiple aspects of real cell behaviour [PDF]
, 2011 The mechanism of eukaryotic chemotaxis remains unclear despite intensive study. The most frequently described mechanism acts through attractants causing actin polymerization, in turn leading to pseudopod formation and cell movement.
Haastert, Peter J.M. van, +26 more
core +5 more sources
Development of taxane resistance in a panel of human lung cancer cell lines [PDF]
, 2008 Using a selection process designed to reflect clinically relevant conditions, a panel of taxane-selected variants were developed to study further the mechanisms of resistance in lung cancer.
Keenan, Joanne +3 more
core +2 more sources