Results 31 to 40 of about 27,881,538 (305)

Engineered basement membranes:from in vivo considerations to cell-based assays [PDF]

, 2018
Improvements in the physiological relevance of cell-based assays have been enabled by the development of various interdisciplinary methods. However, due to their complexity, in vivo structures such as basement membranes (BMs), which regulate the ...
Xiao, Wenjin, Perriman, Adam W., Perriman, Adam, Lennon, Rachel, Welsh, Gavin I., Lennon, Rachel; id_orcid, Perry, Guillaume, Welsh, Gavin   +7 more
core   +1 more source

Relationship Between the Salivary Microbiome and Oral Malodor Metabolites in Older Thai Individuals with Periodontitis and the Cytotoxic Effects of Malodor Compounds on Human Oral Squamous Carcinoma (HSC-4) Cells

Dentistry Journal
Background/Objectives: Halitosis is primarily caused by the activity of oral microorganisms. In this study, we employed metagenomic sequencing and metabolomic approaches to investigate the differences in salivary microbiota and metabolite profiles ...
Witsanu Srila, Kritsana Sripilai, Thunwa Binlateh, Peungchaleoy Thammanichanon, Watcharaphol Tiskratok, Parinya Noisa, Paiboon Jitprasertwong   +6 more
doaj   +1 more source

A tissue culture infectious dose-derived protocol for testing of SARS-CoV-2 neutralization of serum antibodies on adherent cells

STAR Protocols, 2021
Summary: For a cytopathic virus such as severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), the neutralization capacity of serum from convalescent or vaccinated persons or of therapeutic antibodies can be tested on adherent cell cultures ...
Fabio Hasler, Agathe Duda, Thomas M. Kündig, Pål Johansen   +3 more
doaj   +1 more source

Investigating the reproducibility of in vitro cell biology assays using mathematical models [PDF]

, 2017
In vitro cell biology assays are routinely used to study cancer spreading, drug design and tissue repair. However, issues associated with reproducibility are reported in literature.
Jin, Wang
core   +1 more source

Live-cell metabolic analysis of oligodendroglia isolated from postnatal mouse brain and spinal cord

STAR Protocols, 2022
Summary: This protocol describes isolation and live-cell metabolic analysis of O4+ oligodendroglia from brain and spinal cord of postnatal mice. We have optimized existing protocols for O4+ isolation from neonatal brain and expanded the protocol to ...
Luipa Khandker, Teresa L. Wood
doaj   +1 more source

3D culture of alginate-hyaluronic acid hydrogel supports the stemness of human mesenchymal stem cells

Scientific Reports
The three-dimensional (3D) cell culture system is being employed more frequently to investigate cell engineering and tissue repair due to its close mimicry of in vivo microenvironments.
Amorn Pangjantuk, Palakorn Kaokaen, Phongsakorn Kunhorm, Nipha Chaicharoenaudomrung, Parinya Noisa   +4 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Yeast growth selection system for the identification of cell-active inhibitors of [beta]-secretase [PDF]

, 2004
The production and deposition of the cytotoxic Aβ peptide is a central event in the pathogenesis of Alzheimer’s disease (AD). Aβ is excised from the amyloid precursor protein (APP) through sequential actions of the β-secretase, which cleaves at the ...
Middendorp, Oliver M.
core   +1 more source

Toxicity assessment of historical aqueous film-forming foams (AFFFs) using cell-based assays

, 2022
Aqueous film-forming foam (AFFF) has historically contained high concentrations of long-chain per-and polyfluoroalkyl substances (PFAS), which have been linked with adverse health outcomes.
Atinuke F. Ojo, Cheng Peng, Ng, Jack C., Mallavarapu Megharaj, Jack C. Ng, Peng, Cheng, Annamalai, Prasath, Ojo, Atinuke F., Mallavarapu, Mallavarapu, Prasath Annamalai   +9 more
core   +1 more source

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan, Michael Abele, Calogero Virgone, Michaela Kuhlen, Ricardo Lopez‐Almarez, Tal Ben‐Ami, Ewa Bien, Maja Cesen, Malgorzata A. Krawczyk, Andrea Ferrari, Gianni Bisogno, Yves Reguerre, Dominik T. Schneider, Louise Galmiche, Jorg Fuchs, Sarah Braungart, Bilgehan Yalcin, Ines B. Brecht, Daniel Orbach   +18 more
wiley   +1 more source