Results 31 to 40 of about 1,590,893 (316)

Designing personalised cancer treatments [PDF]

, 2013
The concept of personalised medicine for cancer is not new. It arguably began with the attempts by Salmon and Hamburger to produce a viable cellular chemosensitivity assay in the 1970s, and continues to this day.
Ian A. Cree, Cree, Ian A.
core   +1 more source

Relationship Between the Salivary Microbiome and Oral Malodor Metabolites in Older Thai Individuals with Periodontitis and the Cytotoxic Effects of Malodor Compounds on Human Oral Squamous Carcinoma (HSC-4) Cells

Dentistry Journal
Background/Objectives: Halitosis is primarily caused by the activity of oral microorganisms. In this study, we employed metagenomic sequencing and metabolomic approaches to investigate the differences in salivary microbiota and metabolite profiles ...
Witsanu Srila, Kritsana Sripilai, Thunwa Binlateh, Peungchaleoy Thammanichanon, Watcharaphol Tiskratok, Parinya Noisa, Paiboon Jitprasertwong   +6 more
doaj   +1 more source

A tissue culture infectious dose-derived protocol for testing of SARS-CoV-2 neutralization of serum antibodies on adherent cells

STAR Protocols, 2021
Summary: For a cytopathic virus such as severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), the neutralization capacity of serum from convalescent or vaccinated persons or of therapeutic antibodies can be tested on adherent cell cultures ...
Fabio Hasler, Agathe Duda, Thomas M. Kündig, Pål Johansen   +3 more
doaj   +1 more source

Cell-based assays for screening: A practical workshop

, 2022
S.70This workshop, organised by European Pharmaceutical Review, took place on 9-11 December 2014 at Fraunhofer-IME SP in Hamburg, Germany and had support from Biolog, Tecan and PerkinElmer.20Nr.
Gul, S.
core  

Live-cell metabolic analysis of oligodendroglia isolated from postnatal mouse brain and spinal cord

STAR Protocols, 2022
Summary: This protocol describes isolation and live-cell metabolic analysis of O4+ oligodendroglia from brain and spinal cord of postnatal mice. We have optimized existing protocols for O4+ isolation from neonatal brain and expanded the protocol to ...
Luipa Khandker, Teresa L. Wood
doaj   +1 more source

Development of a potency assay for CD34+ cell-based therapy

Scientific Reports, 2023
AbstractWe have previously shown that intracardiac delivery of autologous CD34+ cells after acute myocardial infarction (AMI) is safe and leads to long term improvement. We are now conducting a multicenter, randomized, controlled Phase I/IIb study in post-AMI to investigate the safety and efficacy of intramyocardial injection of expanded autologous ...
Aries, Anne, Vignon, Christine, Zanetti, Céline, Goubaud, Aurélien, Cormier, Arthur, Diederichs, Anne, Lahlil, Rachid, Hénon, Philippe, Garitaonandia, Ibon   +8 more
openaire   +3 more sources

3D culture of alginate-hyaluronic acid hydrogel supports the stemness of human mesenchymal stem cells

Scientific Reports
The three-dimensional (3D) cell culture system is being employed more frequently to investigate cell engineering and tissue repair due to its close mimicry of in vivo microenvironments.
Amorn Pangjantuk, Palakorn Kaokaen, Phongsakorn Kunhorm, Nipha Chaicharoenaudomrung, Parinya Noisa   +4 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Additive mixture effects of estrogenic chemicals in human cell-based assays can be influenced by inclusion of chemicals with differing effect profiles

, 2012
Copyright @ 2012 The Authors. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and 85 reproduction in any medium, provided the original author and source
Kortenkamp Andreas, Evans, RM, Kortenkamp, A, Andreas Kortenkamp, Evans Richard Mark, Scholze Martin, Scholze, M, Martin Scholze, Richard Mark Evans   +8 more
core   +1 more source

Identification of major factors influencing ELISpot-based monitoring of cellular responses to antigens from mycobacterium tuberculosis [PDF]

, 2009
A number of different interferon-c ELISpot protocols are in use in laboratories studying antigen-specific immune responses. It is therefore unclear how results from different assays compare, and what factors most significantly influence assay outcome ...
Pathan, Ansar A, Mascart Françoise, Hazel M. Dockrell, Simone A. Joosten, Steven G. Smith, Ottenhoff, THM, Françoise Mascart, Steven G Smith, Pathan Ansar A., Simone A Joosten, Verscheure, Virginie, Ottenhoff Tom H. M., Smith, SG, Hazel M Dockrell, Verscheure, V, Smith, Steven G, McShane Helen, Ottenhoff, TH, Virginie Verscheure, Pathan, AA, Tom H. M. Ottenhoff, Joosten, Simone A, Ansar A. Pathan, Ottenhoff, Tom HM, Tom H M Ottenhoff, Helen McShane, Ansar A Pathan, Joosten, SA, Mascart, F, Joosten Simone A., Ottenhoff, Tom H M, Mascart, Françoise, Dockrell Hazel M., Verscheure Virginie, Dockrell, HM, Dockrell, Hazel M, McShane, H, McShane, Helen, Smith Steven G.   +38 more
core   +1 more source