Results 31 to 40 of about 8,914,547 (304)

Cell-free Screening for NOX Inhibitors

Chemistry & Biology, 2012
NOX enzymes are major ROS generators in pathological states and represent a promising pharmacological target. In this issue of Chemistry & Biology, Smith and colleagues developed an original and elegant cell-free assay to identify specific Nox2 inhibitors in a high throughput manner.
Bedard, Karen, Jaquet, Vincent
openaire   +2 more sources

Breast Milk from Tanzanian Women has Divergent Effects on Cell-Free and Cell-Associated HIV-1 Infection in Vitro. [PDF]

, 2012
Transmission of HIV-1 during breastfeeding is a significant source of new pediatric infections in sub-Saharan Africa. Breast milk from HIV-positive mothers contains both cell-free and cell-associated virus; however, the impact of breast milk on HIV-1 ...
Ruth I Connor, Alexandra L Howell, Molly L Housman, Lee, F.V, Housman, M.L., Zain-Ul-Abideen Muhammad, Frederick V Lee, Zain-Ul-Abideen, M., Connor, R.I, Connor Ruth I., Zain-Ul-Abideen, Muhammad, Lyimo, M.A., Howell, Alexandra L, Lyimo, Magdalena A, Magdalena A Lyimo, Howell Alexandra L., Housman, Molly L, Mosi, M.N, Muhammad Zain-Ul-Abideen, Howell, A.L, Lee, Frederick V, Mosi, Matilda Ngarina, Matilda Ngarina Mosi, Connor, Ruth I, Lyimo Magdalena A., Housman Molly L., Mosi Matilda Ngarina, Lee Frederick V.   +27 more
core   +1 more source

Circulating Cell-Free DNA in Cancer

, 2014
This papers deals with the preanalytical and analytical phase of cell-free DNA analysis, highlighting some criticism on sample collection and extraction. We describe a method to accurately quantify total cfDNA in plasma and our particular approach to the measurement of tumor deriving cfDNA.
PINZANI, PAMELA, SALVIANTI, FRANCESCA, ORLANDO, CLAUDIO, PAZZAGLI, MARIO   +3 more
openaire   +3 more sources

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

HRT-Net: A Cell-free Cooperative Sensing Method Based on Attention-weighted Hierarchical Network

Leida xuebao
This paper proposes an intelligent framework based on a cell-free network architecture, called HRT-Net. HRT-Net is designed to enhance multi-station collaborative sensing problems for Dual-Functional Radar-Communication (DFRC) systems, offering accurate ...
Shengheng LIU, He YAN, Xingkang LI, Dazhuan XU, Dongming WANG, Yongming HUANG   +5 more
doaj   +1 more source

Diurnal stability of cell-free DNA and cell-free RNA in human plasma samples [PDF]

Scientific Reports, 2020
AbstractMany emerging technologies are reliant on circulating cell-free DNA (cfDNA) and cell-free RNA (cfRNA) applications in the clinic. However, the impact of diurnal cycles or daily meals on circulating analytes are poorly understood and may be confounding factors when developing diagnostic platforms.
Josiah T. Wagner, Hyun Ji Kim, Katie C. Johnson-Camacho, Taylor Kelley, Laura F. Newell, Paul T. Spellman, Thuy T. M. Ngo   +6 more
openaire   +3 more sources

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

Progress in the Development of Stem Cell-Derived Cell-Free Therapies for Skin Aging

, 2023
Yoan Chou,1 Nayla Majeda Alfarafisa,2 Maiko Ikezawa,3 Astrid Feinisa Khairani1,2 1Graduate School of Master Program in Anti Aging and Aesthetic Medicine, Faculty of Medicine, Universitas Padjadjaran, Jatinangor, West Java, Indonesia; 2Department of ...
Ikezawa M, Chou Y, Alfarafisa NM, Khairani AF   +3 more
core  

Advanced Glycation End-Products-, C-Type Lectin- and Cysteinyl/ Leukotriene-Receptors in Distinct Mesenchymal Stromal Cell Populations: Differential Transcriptional Profiles in Response to Inflammation

Cell Journal, 2018
Objective We aimed at characterizing the transcription profiles of immunological receptors associated with the biology of mesenchymal stromal cells (MSCs).
Mehdi Najar, Mohammad Fayyad-Kazan, Gordana Raicevic, Hussein Fayyad-Kazan, Nathalie Meuleman, Dominique Bron, Laurence Lagneaux   +6 more
doaj   +1 more source

Decentralizing Cell-Free RNA Sensing With the Use of Low-Cost Cell Extracts

Frontiers in Bioengineering and Biotechnology, 2021
Cell-free gene expression systems have emerged as a promising platform for field-deployed biosensing and diagnostics. When combined with programmable toehold switch-based RNA sensors, these systems can be used to detect arbitrary RNAs and freeze-dried ...
Anibal Arce, Anibal Arce, Anibal Arce, Fernando Guzman Chavez, Chiara Gandini, Juan Puig, Juan Puig, Tamara Matute, Tamara Matute, Jim Haseloff, Neil Dalchau, Jenny Molloy, Keith Pardee, Fernán Federici, Fernán Federici, Fernán Federici, Fernán Federici   +16 more
doaj   +1 more source