Results 61 to 70 of about 2,906,730 (289)

Do-it-yourself instrument integration into an existing mammalian cell line development automation platform

SLAS Technology
Laboratory automation in the biopharmaceutical industry as a rule requires contracted service from highly professional automation solution provider, at times involving the purchase and development of specialized or customized hardware and software, which
Jie Ding, Kee Wee Tan, Xiaoyue Chen
doaj   +1 more source

Cell-Free Expression to Probe Co-Translational Insertion of an Alpha Helical Membrane Protein

Frontiers in Molecular Biosciences, 2022
The majority of alpha helical membrane proteins fold co-translationally during their synthesis on the ribosome. In contrast, most mechanistic folding studies address refolding of full-length proteins from artificially induced denatured states that are ...
Laura R. Blackholly, Nicola J. Harris, Heather E. Findlay, Paula J. Booth   +3 more
doaj   +1 more source

Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy, Elizabeth L. Seashore, W. Susan Cheng, Shondra Clay, Jessica A. Casas, Jennifer H. Foster   +5 more
wiley   +1 more source

In situ Adipogenesis in Biomaterials Without Cell Seeds: Current Status and Perspectives

Frontiers in Cell and Developmental Biology, 2021
For cosmetic and reconstructive purposes in the setting of small-volume adipose tissue damage due to aging, traumatic defects, oncological resections, and degenerative diseases, the current strategies for soft tissue replacement involve autologous fat ...
Jiqiao Yang, Jiqiao Yang, Chen Zhou, Jingyang Fu, Qianru Yang, Tao He, Qiuwen Tan, Qiuwen Tan, Qing Lv   +8 more
doaj   +1 more source

The Efficacy and Safety of Bevacizumab/Irinotecan/Temozolomide (BIT) for Relapsed/Refractory Neuroblastoma: The UK Children's Cancer and Leukaemia Group Experience

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Patients with high‐risk neuroblastoma who either are refractory to induction chemotherapy or relapse following multi‐modal treatment have a dismal prognosis. Based on data from the BEACON trial, since 2021 the UK national guidelines recommend bevacizumab, irinotecan, and temozolomide (BIT) for patients with relapsed/refractory ...
Thomas J. Jackson, Menna Shamma, Upeka Senanayake, Shaimaa Sahmoud, Kathleen Duffin, Victoria Howard, David King, Ayesha Fathani, Blanche Lumb, Andrei Pobischan, Irum Latif Memon, Monzir Ahmed, Rhian Thomas, Gerard Millen, Yasmeen Alomari, Sucheta Vaidya, Lynley V. Marshall, Sally L. George, Ramya Ramanujachar, Juliet Gray, Paola Angelini   +20 more
wiley   +1 more source

Cell-Free Synthesis Meets Antibody Production: A Review

Antibodies, 2015
Engineered antibodies are key players in therapy, diagnostics and research. In addition to full size immunoglobulin gamma (IgG) molecules, smaller formats of recombinant antibodies, such as single-chain variable fragments (scFv) and antigen binding ...
Marlitt Stech, Stefan Kubick
doaj   +1 more source

On Scalability of FDD-Based Cell-Free Massive MIMO Framework

Sensors, 2023
Cell-free massive multiple-input multiple-output (MIMO) systems have the potential of providing joint services, including joint initial access, efficient clustering of access points (APs), and pilot allocation to user equipment (UEs) over large coverage ...
Beenish Hassan, Sobia Baig, Saad Aslam
doaj   +1 more source

Anti-inflammatory and antioxidant properties of HDLs are impaired in type 2 diabetes. [PDF]

, 2011
ObjectiveIn mice, 4F, an apolipoprotein A-I mimetic peptide that restores HDL function, prevents diabetes-induced atherosclerosis. We sought to determine whether HDL function is impaired in type 2 diabetic (T2D) patients and whether 4F treatment improves
Boldrini, Beatrice, Ferrannini, Ele, Fogelman, Alan M, Imaizumi, Satoshi, Morgantini, Cecilia, Natali, Andrea, Navab, Mohamad, Reddy, Srinivasa T   +7 more
core   +1 more source

Implementing Health‐Related Quality of Life Assessment in Pediatric Oncology: A Feasibility Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background There is growing interest in embedding health‐related quality of life (HRQoL) assessment and patient‐reported outcome measures (PROMs) within clinical cancer care. This study evaluated the feasibility, acceptability, and usability of implementing an electronic PROM (ePROM) platform to measure HRQoL in children with cancer ...
Mikaela Doig, Sophie Jessop, Jordan R. Hansford, Hien Le, Matthew O'Connor, Peter Gorayski, Andrew Cunningham, Amanda Hutchinson, Victoria Bedford, Eva Bezak, Nayana Parange, Kelly Skelton, Timothy Price, Michala Short   +13 more
wiley   +1 more source

Chacma baboon natural anticoagulants and factor VIII activities

Scientific Reports
Non-human primates are useful models of human haemostasis, but distinctions do exist. These differences are essential to identify and quantify to better characterise the Chacma baboon’s coagulation system.
Quintin Andre van Staden, Sarah Meiring Muriel, Conradie Charmaine, Joubert Jaco   +3 more
doaj   +1 more source