Results 241 to 250 of about 1,636,041 (314)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Use of cell-free DNA in early detection of lung cancer: a proof-of concept study. [PDF]

BMC Cancer
White LL, Maiyani M, Quintana LM, Powers JD, Nichols LE, Dollar B, Bedoy R, Martinez AE, Feigelson HS.   +8 more
europepmc   +1 more source

Culture-Negative Subacute Lactobacillus Endocarditis Diagnosed by Microbial Cell-Free DNA Sequencing

Abduljabar Adi, Sandrine Lebrun, Maiko Kondo, Miguel Alvarez Villela, Joao Daniel Fontes   +4 more
openalex   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Dual-Caspase-Mediated Apoptosis Underlies Peritoneal Cell-Free DNA Release After PD-Related Peritonitis. [PDF]

Genes (Basel)
Virzì GM, Milan Manani S, Marcello M, Porrovecchio A, Ronco C, Zanella M.   +5 more
europepmc   +1 more source

Circulating Cell-Free DNA

, 2019
Yingli Sun, Ke An, Caiyun Yang
openaire   +2 more sources

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

The Progress, Pitfalls and Paediatric Perspectives of Donor-Derived Cell-Free DNA in Heart Transplants. [PDF]

Acta Paediatr
Böhmer J.
europepmc   +1 more source