Results 221 to 230 of about 1,636,041 (314)

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Expanding role of cell-free DNA for the early diagnosis and monitoring of pulmonary diseases. [PDF]

Chin Med J (Engl)
Yang L, Gu Y, Shao J, Zhang L, Wang C.
europepmc   +1 more source

Donor-specific Cell-free DNA as a Biomarker in Solid Organ Transplantation. A Systematic Review

, 2018
Simon Knight, Adam M. Thorne, Maria Letizia Lo Faro   +2 more
openalex   +2 more sources

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

5-Hydroxymethylcytosine signatures in circulating cell-free DNA as potential diagnostic markers for breast cancer

Nadire Aishan, Siwei Ju, Zhongqiu Zheng, Yongxia Chen, Qingna Meng, Qina He, Jiahang Zhang, Jiaheng Lang, Bojian Xie, Lidan Jin, Jun Shen, Yi Lu, Yangjun Cai, Feiyang Ji, Feilin Cao, Linbo Wang   +15 more
openalex   +2 more sources

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Accurate and reliable detection of clonal hematopoiesis in plasma cell-free DNA. [PDF]

Blood Adv
Parker AC, Van Amburg JC, Pershad Y, Ong DA, Hoey KJ, Farady CJ, Rauch PJ, Mendelson MM, Heimlich JB, Ferrell PB, Bick AG.   +10 more
europepmc   +1 more source

Plasma cell-free DNA as predictor of disease status in patients with differentiated thyroid cancer - a prospective study from a tertiary care institution [PDF]

Rashi Goel, Swayamjeet Satapathy, Kunal Ramesh Chandekar, Sanjana Ballal, Shipra Agarwal, Suryanarayan S. V. Deo, Madhavi Tripathi, Chandrasekhar Bal   +7 more
openalex   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Multimodal analysis of cell-free DNA to improve early detection of gastric cancer. [PDF]

BMC Cancer
Long VD, Huynh LAK, Vo DH, Nguyen THH, Van TTV, Nguyen GTH, Doan TN, Nguyen VH, Tran QD, Dang QT, Nguyen VTA, Ho LMQ, Ha TPD, Dang TND, Nguyen PTN, Nguyen KT, Ho VC, Le TL, Nguyen THN, Tu NH, Tran TS, Jasmine TX, Vo TL, Nai THT, Tran TT, Truong MH, Tran NC, Nguyen TC, Nguyen TT, Le BT, Tang VP, Nguyen TT, Nguyen AT, Vu HG, Van Phan T, Nguyen TNT, Cao HA, Nguyen TH, Tu LN, Giang H, Phan MD, Nguyen HN, Nguyen VTC, Tran LS.   +43 more
europepmc   +1 more source