Elevations in Donor-Derived Cell-Free DNA and Allograft Outcomes in Kidney Transplantation. [PDF]
Klein JA +53 more
europepmc +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Early detection of gastric cancer with the assistance of cell-free DNA fragmentomics. [PDF]
Huang X +17 more
europepmc +1 more source
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
Prenatal cell-free DNA methylome detects association with autism and maternal obesity. [PDF]
Williams LA +6 more
europepmc +1 more source
Diagnostic Testing After Positive Cell-Free DNA Screening for Sex Chromosome Aneuploidies: Clinical and Socioeconomic Determinants. [PDF]
Stevens BK +10 more
europepmc +1 more source
Identification of a G-quadruplex-forming cell-free DNA fragment as a biomarker for the precise diagnosis of hepatocellular carcinoma. [PDF]
Sun J +5 more
europepmc +1 more source
Cell-free DNA genomic and fragmentomic features for early outcome prediction in large B cell lymphoma. [PDF]
Wang S +35 more
europepmc +1 more source
Correction: Assessment of radiotherapy effect and toxicity using tissue-associated DNA methylation markers in cell-free DNA: a study on prostate cancer. [PDF]
Bahtiyar N +6 more
europepmc +1 more source

