Results 231 to 240 of about 1,636,041 (314)

Focused Size Selection of Cell-Free DNA Samples for Liquid Biopsy Applications that Rely on Next-Generation Sequencing

, 2019
Christopher K. Raymond
openalex   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Cell-Free DNA Hypermethylation in Patients with Acute Pancreatitis. [PDF]

Int J Mol Sci
Al-Mashat H, Baddoo DR, Lundbye-Christensen S, Madsen PH, Pedersen IS, Krarup HB, Stubbe BE, Thorlacius-Ussing O, Henriksen SD.   +8 more
europepmc   +1 more source

CELL-FREE DNA AS A FACTOR OF STRESS SIGNALING

Pavel E. Umriukhin, Svetlana Kostuk, Elena Miheeva, Nikita Shabalin   +3 more
openalex   +1 more source

Utilization of cell-free DNA metagenomic analysis for early detection and microbial identification in prosthetic joint infections: a prospective cohort study in Korea [PDF]

Jung Ah Lee, Dongju Won, Eun Hwa Lee, Seung‐Tae Lee, Kwan Kyu Park, Saeam Shin, Su Jin Jeong   +6 more
openalex   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell-free DNA. [PDF]

Mol Oncol
Maansson CT, Nielsen AL, Sorensen BS.
europepmc   +1 more source

Donor-derived cell-free DNA correlates with acute rejection measurements.

Michelle Mendiola Pla (16400583), Joseph A. Prinz (8433045), Kishen Mitra (21738851), Franklin H. Lee (16400586), Matthew F. Smith (18400512), Alejandro Alvarez Lobo (21738848), Carmelo A. Milano (16400607), Dawn E. Bowles (12068354), Devjanee Swain-Lenz (21738845)   +8 more
openalex   +1 more source

Plasma Cell-free DNA Concentration and Outcomes from Taxane Therapy in Metastatic Castration-resistant Prostate Cancer from Two Phase III Trials (FIRSTANA and PROSELICA)

, 2018
Niven Mehra, David Dolling, Semini Sumanasuriya, Rossitza Christova, Lorna Pope, Suzanne Carreira, George Seed, Wei Yuan, Jane Goodall, Emma Hall, Penny Flohr, Gunther Boysen, Diletta Bianchini, Oliver Sartor, Mario A. Eisenberger, Karim Fizazi, Stéphane Oudard, Mustapha Chadjaa, Sandrine Macé, Johann S. de Bono   +19 more
openalex   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source