Results 201 to 210 of about 10,355,590 (280)

Impact of Prenatal Cell-Free DNA Screening on Sex Chromosome Aneuploidy Diagnoses in Infants and Children. [PDF]

Prenat Diagn
Kim DeLuca E, Wu AC, Zhang F, Wright DR, Kaimal A, Lee T.   +5 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Toward generalizable prediction of cancer signal using a cell-free DNA language model. [PDF]

Cell Rep Med
Xu Y, Bao H, Huang D, Zhang K, Zhu J, Yang L, Fu S, Chang Z, Zhang J, Chang S, Zhu B, Wu S, Yang S, Wu X, Shao Y.   +14 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Using cell-free DNA tumor methylation score to detect and monitor cholangiocarcinoma. [PDF]

HPB (Oxford)
Javanshir S, Angeli-Pahim I, Iyengar P, Chambers A, Smarandache IM, Ganguli R, Shrestha A, Squadrito J, Abreu A, Suchan G, Rizk C, Palaz F, Hughes SJ, Sahin I, Grajo JR, Duarte S, Zarrinpar A.   +16 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

<i>GastroAlert</i>: a multimodal epigenetic blood test for early detection of gastric cancer using cell-free DNA. [PDF]

Mil Med Res
Xu YJ, Xu JF, Xia CF, Wu YJ, Li DG, Liu TY, Cui HP, Zhang J, Shang L, Chen WQ.   +9 more
europepmc   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Circulating Cell-Free DNA [PDF]

, 2020
openaire   +1 more source

Prognostic Significance of Cell-Free DNA Derived 5-Hydroxymethylcytosine Signatures in Newly Diagnosed Multiple Myeloma. [PDF]

JCO Precis Oncol
Zhang Z, Derman B, Wang B, Kowitwanich K, Cursio J, Gao L, Appelbaum D, He C, Jakubowiak A, Zhang W, Chiu BC.   +10 more
europepmc   +1 more source