Results 321 to 330 of about 3,251,205 (352)

Cell-Free DNA Integrity: Applications

2018
Cell-free DNA integrity (cfDNAi) could be a valuable biomarker for solid tumors, to define prognosis and response to therapy. Several elements have been studied for cfDNAi, such as specific genes involved in cancer progression or repetitive DNA sequences as surrogate markers for the whole circulating DNA.However, the lack of a standardized method for ...
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Epigenetic Characterization of Cell-Free DNA

2018
Cell-free DNA can be evaluated for the epigenetic component. Epigenetic alterations consist of changes in gene functions that do not involve changes in DNA sequence. The mainly studied epigenetic alteration is DNA methylation occurring at CpG islands in the promoter regions for which several literature data showed clinical relevance. This chapter is an
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Methodological Variables in the Analysis of Cell-Free DNA

2016
In recent years, cell-free DNA (cfDNA) analysis has received increasing amounts of attention as a potential non-invasive screening tool for the early detection of genetic aberrations and a wide variety of diseases, especially cancer. However, except for some prenatal tests and BEAMing, a technique used to detect mutations in various genes of cancer ...
Bronkhorst, Abel Jacobus, Aucamp, Janine, Pretorius, Piet J.   +2 more
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Cell-Free DNA Testing

2019
Cell-free DNA (cfDNA) is an emerging biomarker that already has significant clinical utility. With further development, cfDNA characterization may become a ubiquitous companion modality for diagnosis, prognosis, treatment selection, and recurrence detection for myriad medical conditions.
Brennan Decker, Lynette M. Sholl
openaire   +1 more source

Cell-Free DNA in the Management of Colorectal Cancer

2019
Colorectal cancer is one of the leading cause of death by cancer worldwide in both men and women. Liquid biopsy belongs nowadays to the landscape of cancer management biological tools. In this chapter, we will describe and discuss the actual, potential and future applications of cfDNA analysis in plasma of patients with colorectal cancer in early or ...
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Cell-Free DNA

Obstetrics and Gynecology Clinics of North America, 2018
Kristin D. Gerson, Barbara M. O’Brien
openaire   +1 more source

Analytical and clinical validation of a microbial cell-free DNA sequencing test for infectious disease

Nature Microbiology, 2019
T. Blauwkamp, Simone A. Thair, Michael J. Rosen, L. Blair, M. S. Lindner, I. Vilfan, Trupti Kawli, F. Christians, S. Venkatasubrahmanyam, Gregory D. Wall, A. Cheung, Zoë N. Rogers, G. Meshulam-Simon, L. Huijse, S. Balakrishnan, J. Quinn, D. Hollemon, David K. Hong, M. L. Vaughn, Mickey Kertesz, S. Bercovici, J. Wilber, Samuel Yang   +22 more
semanticscholar   +1 more source

Cell-free DNA

Clinics in Laboratory Medicine, 2016
Pe’er Dar, Hagit Shani, Mark I. Evans
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Circulating tumor DNA in advanced solid tumors: Clinical relevance and future directions

Ca-A Cancer Journal for Clinicians, 2021
Heather A Parsons, Atish Choudhury, Michael L Cheng   +2 more
exaly  

Liquid biopsies: donor-derived cell-free DNA for the detection of kidney allograft injury

Nature Reviews Nephrology, 2021
M. Oellerich, K. Sherwood, P. Keown, E. Schütz, J. Beck, J. Stegbauer, L. Rump, P. Walson   +7 more
semanticscholar   +1 more source