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Use of cell-free DNA in early detection of lung cancer: a proof-of concept study. [PDF]
White LL +8 more
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Whole-genome sequencing of cell-free DNA for assessment of minimal residual disease in high-risk smoldering multiple myeloma. [PDF]
Baker C +21 more
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Cell-Free DNA and Apoptosis: How Dead Cells Inform About the Living
Trends in Molecular Medicine, 2020Cell-free DNA (cfDNA) is evolving into a widely used prognostic and predictive biomarker, particularly in oncology. However, its versatile clinical use precedes a profound understanding of the underlying biology of cfDNA release.
Ellen Heitzer, Michael Speicher
exaly +2 more sources
Anais do 6º Simpósio de Saúde: Saúde 4.0 - Tecnologia e Inovação, 2023
O DNA livre de células, ou cfDNA, tem sido cada vez mais reconhecido como um biomarcador importante em diversas áreas da medicina.
Diogo Barcelos Almeida +6 more
openaire +2 more sources
O DNA livre de células, ou cfDNA, tem sido cada vez mais reconhecido como um biomarcador importante em diversas áreas da medicina.
Diogo Barcelos Almeida +6 more
openaire +2 more sources
Cell-Free DNA in Dermatology Research
Journal of Investigative Dermatology, 2022In various diseases, particularly cancer, cell-free DNA (cfDNA) has been widely studied as a marker of disease prognosis or to facilitate the detection of therapeutic targets. In dermatology, most studies have focused on melanoma; other skin diseases such as vascular malformations and psoriasis have also been examined. Genetic alterations unique to the
Jennifer M. Wiggins +2 more
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Epigenetics, fragmentomics, and topology of cell-free DNA in liquid biopsies
Science, 2021Enhancing liquid biopsies Liquid biopsies, analyses of cell-free DNA that circulates in the blood, can be used in prenatal testing, oncology, and to monitor organ transplant recipients. Lo et al. review the nongenetic information that can be gleaned from
Y. Lo, D. S. Han, P. Jiang, R. Chiu
semanticscholar +1 more source
Cell-free DNA: Preanalytical variables
Clinica Chimica Acta, 2015Since the discovery of cell-free DNA (cfDNA) in human blood, most studies have focused on diagnostic and prognostic uses of these markers for solid tumors. Except for some prenatal tests and BEAMing, cfDNA analysis has not yet been translated to clinical practice and routine application appears distant. This can be attributed to overlapping factors: (i)
Abel Jacobus Bronkhorst +2 more
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Liquid Biopsy of Methylation Biomarkers in Cell-Free DNA.
Trends in Molecular Medicine, 2021Liquid biopsies, in particular, analysis of cell-free DNA (cfDNA), have emerged as a promising noninvasive diagnostic approach in oncology. Abnormal distribution of DNA methylation is one of the hallmarks of many cancers and methylation changes occur ...
Hui‐yan Luo +4 more
semanticscholar +1 more source

