Results 281 to 290 of about 1,636,041 (314)
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The Journal of molecular diagnostics : JMD, 2017
The analysis of cell-free DNA (cfDNA) as a sensitive biomarker for cancer diagnosis and monitoring has resulted in a need for efficient and standardized cfDNA isolation. In this study, we compared the isolation efficiency of the QIAamp circulating nucleic acid kit (QIA) with four other cfDNA isolation kits: the PME free-circulating DNA Extraction Kit ...
Sorber, Laure +6 more
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The analysis of cell-free DNA (cfDNA) as a sensitive biomarker for cancer diagnosis and monitoring has resulted in a need for efficient and standardized cfDNA isolation. In this study, we compared the isolation efficiency of the QIAamp circulating nucleic acid kit (QIA) with four other cfDNA isolation kits: the PME free-circulating DNA Extraction Kit ...
Sorber, Laure +6 more
openaire +3 more sources
Cell-Free DNA Integrity: Applications
2018Cell-free DNA integrity (cfDNAi) could be a valuable biomarker for solid tumors, to define prognosis and response to therapy. Several elements have been studied for cfDNAi, such as specific genes involved in cancer progression or repetitive DNA sequences as surrogate markers for the whole circulating DNA.However, the lack of a standardized method for ...
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Epigenetic Characterization of Cell-Free DNA
2018Cell-free DNA can be evaluated for the epigenetic component. Epigenetic alterations consist of changes in gene functions that do not involve changes in DNA sequence. The mainly studied epigenetic alteration is DNA methylation occurring at CpG islands in the promoter regions for which several literature data showed clinical relevance. This chapter is an
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Methodological Variables in the Analysis of Cell-Free DNA
2016In recent years, cell-free DNA (cfDNA) analysis has received increasing amounts of attention as a potential non-invasive screening tool for the early detection of genetic aberrations and a wide variety of diseases, especially cancer. However, except for some prenatal tests and BEAMing, a technique used to detect mutations in various genes of cancer ...
Bronkhorst, Abel Jacobus +2 more
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2019
Cell-free DNA (cfDNA) is an emerging biomarker that already has significant clinical utility. With further development, cfDNA characterization may become a ubiquitous companion modality for diagnosis, prognosis, treatment selection, and recurrence detection for myriad medical conditions.
Brennan Decker, Lynette M. Sholl
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Cell-free DNA (cfDNA) is an emerging biomarker that already has significant clinical utility. With further development, cfDNA characterization may become a ubiquitous companion modality for diagnosis, prognosis, treatment selection, and recurrence detection for myriad medical conditions.
Brennan Decker, Lynette M. Sholl
openaire +1 more source
Cell-Free DNA in the Management of Colorectal Cancer
2019Colorectal cancer is one of the leading cause of death by cancer worldwide in both men and women. Liquid biopsy belongs nowadays to the landscape of cancer management biological tools. In this chapter, we will describe and discuss the actual, potential and future applications of cfDNA analysis in plasma of patients with colorectal cancer in early or ...
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Obstetrics and Gynecology Clinics of North America, 2018
Kristin D. Gerson, Barbara M. O’Brien
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Kristin D. Gerson, Barbara M. O’Brien
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Circulating tumor DNA in advanced solid tumors: Clinical relevance and future directions
Ca-A Cancer Journal for Clinicians, 2021Michael L Cheng +2 more
exaly
Proceedings of the National Academy of Sciences of the United States of America, 2021
Peiyong Jiang +2 more
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Peiyong Jiang +2 more
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