Results 291 to 300 of about 3,251,205 (352)

Accurate and reliable detection of clonal hematopoiesis in plasma cell-free DNA. [PDF]

Blood Adv
Parker AC, Van Amburg JC, Pershad Y, Ong DA, Hoey KJ, Farady CJ, Rauch PJ, Mendelson MM, Heimlich JB, Ferrell PB, Bick AG.   +10 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Cell-Free DNA Hypermethylation in Patients with Acute Pancreatitis. [PDF]

Int J Mol Sci
Al-Mashat H, Baddoo DR, Lundbye-Christensen S, Madsen PH, Pedersen IS, Krarup HB, Stubbe BE, Thorlacius-Ussing O, Henriksen SD.   +8 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell-free DNA. [PDF]

Mol Oncol
Maansson CT, Nielsen AL, Sorensen BS.
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Mindful diagnostics in culture-negative endocarditis: early noninvasive diagnosis of <i>Tropheryma whipplei</i> by plasma microbial cell-free DNA. [PDF]

Antimicrob Steward Healthc Epidemiol
Jain A, Khalil S, Sohail MR, Lelenwa LC, Garcia-Sayan E, Liao KK, Hamdi A, Lasco T, Al Mohajer M.   +8 more
europepmc   +1 more source

Tumor-derived cell-free DNA detected in cerebrospinal fluid enables minimally invasive profiling of pediatric brain tumors. [PDF]

J Clin Invest
Nobre L, Nakano Y, Burns I, Siddaway R, Zápotocky M, Johnson M, Rana M, Li C, Lyn RK, Yuditskiy R, Ku M, Sheth J, Levine AB, Nesvick CL, Das A, Cacciotti C, Zelcer S, Climans SA, MacDonald M, Negm L, Chung J, Bennett J, Bondoc A, Loukides J, Stengs L, Edwards M, Bouffet E, Ramaswamy V, Liu AP, Huang A, Bartels U, Dirks PB, Tabori U, Hawkins C.   +33 more
europepmc   +1 more source

Donor-derived cell-free DNA as a noninvasive biomarker for diagnosis and monitoring of acute rejection after liver transplantation. [PDF]

Front Immunol
Deng Z, Yang M, Cheng Q, Lu Z, Ye Q, Xiong Y, Ye S.   +6 more
europepmc   +1 more source