Results 31 to 40 of about 239,910 (281)
mBio, 2023 Wall-less bacteria are broadly distributed in diverse habitats. They evolved from a common ancestor within the Firmicutes phylum through reductive evolution.
Rikuan Zheng +4 more
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Cell-free fetal nucleic acids in amniotic fluid [PDF]
Human Reproduction Update, 2010 Research into cell-free fetal (cff) nucleic acids has primarily focused on maternal plasma; however, cff DNA and RNA are also detectable in other body fluids such as amniotic fluid (AF). In AF, cff DNA is present in much greater concentrations than in maternal plasma and represents a pure fetal sample uncontaminated by maternal- and trophoblast-derived
L, Hui, D W, Bianchi
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Cancer Biology & Medicine, 2016 Circulating free nucleic acids; cell free DNA and circulating micro-RNA, are found in the plasma of patients with hematologic and solid malignancies at levels higher than that of healthy individuals.
Jay Hocking +3 more
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Plasma GBP2 promoter methylation is associated with advanced stages in breast cancer [PDF]
Genetics and Molecular Biology, 2020 Blood methylated cell-free DNA (cfDNA) as a minimally invasive cancer biomarker has great importance in cancer management. Guanylate binding protein 2 (GBP2) has been considered as a possible controlling factor in tumor development.
Farzaneh Rahvar +2 more
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Human Genomics, 2022 Background Blood plasma, one of the most studied liquid biopsies, contains various molecules that have biomarker potential for cancer detection, including cell-free DNA (cfDNA) and cell-free RNA (cfRNA). As the vast majority of cell-free nucleic acids in
Jill Deleu +10 more
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Circulating nucleic acids in the plasma and serum as potential biomarkers in neurological disorders [PDF]
Brazilian Journal of Medical and Biological Research, 2020 Neurological diseases are responsible for approximately 6.8 million deaths every year. They affect up to 1 billion people worldwide and cause significant disability and reduced quality of life.
D.C.F. Bruno +7 more
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Pre-analytical issues in liquid biopsy – where do we stand?
Journal of Laboratory Medicine, 2020 It is well documented that in the chain from sample to the result in a clinical laboratory, the pre-analytical phase is the weakest and most vulnerable link. This also holds for the use and analysis of extracellular nucleic acids.
Fleischhacker Michael, Schmidt Bernd
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TLR and NKG2D signaling pathways mediate CS-induced pulmonary pathologies. [PDF]
PLoS ONE, 2013 Long-term exposure to cigarette smoke (CS) can have deleterious effects on lung epithelial cells including cell death and the initiation of inflammatory responses.
Brian W Wortham +4 more
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PLoS ONE, 2019 Urine holds great promise as a non-invasive sampling method for molecular diagnostics. The cell-free nucleic acids of urine however are small, labile, and difficult to purify.
Kayvan Zainabadi +3 more
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Cell-free Fetal Nucleic Acid Identifier Markers in Maternal Circulation
Advanced Biomedical Research, 2017 From the discovery of cell-free fetal (cff)-DNA in 1997 so far, many studies have been performed on various aspects of cff-nucleic acid. It is undoubted that currently, invasive prenatal diagnosis progresses to the noninvasive test. However, there are many problems.
Mahboubeh Ramezanzadeh +2 more
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