Results 21 to 30 of about 265,282 (276)
Cell-free fetal nucleic acids as prenatal biomarkers
Expert Opinion on Medical Diagnostics, 2011 Cell-free fetal nucleic acids in maternal plasma or serum have become important tools in the pursuance of new methods for non-invasive prenatal diagnosis, such as the determination of fetal blood groups and fetal gender. During these pioneering explorations, elevations in the concentration of these new-found biological analytes were noted in several ...
Visca, E. +3 more
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Cell-Free Nucleic Acids in Cardiovascular Disease: From Biomarkers to Mechanistic Drivers and Therapeutic Opportunities. [PDF]
CellsCardiovascular disease (CVD) remains the leading cause of morbidity and mortality worldwide, with heart failure (HF) representing a major contributor to hospitalizations, healthcare costs, and death.
Morgan H +10 more
europepmc +2 more sources
Cell-free Nucleic Acids as Potential Markers for Preeclampsia
Placenta, 2011 Preeclampsia is one of the leading causes of maternal and fetal/neonatal mortality and morbidity worldwide. Therefore, widely applicable and affordable tests are needed to make an early diagnosis before the occurrence of the clinical symptoms. Circulating cell-free nucleic acids in plasma and serum are novel biomarkers with promising clinical ...
Hahn, S. +3 more
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Precise, Orthogonal Remote-Control of Cell-Free Systems Using Photocaged Nucleic Acids
Journal of the American Chemical Society, 2023 Cell-free expression of a gene to protein has become a vital tool in nanotechnology and synthetic biology. Remote-control of cell-free systems with multiple, orthogonal wavelengths of light would enable precise, noninvasive modulation, opening many new applications in biology and medicine.
Giacomo Mazzotti +2 more
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Cell-Free Nucleic Acids. [PDF]
Int J Mol Sci, 2019 The discovery of cell-free DNA (cfDNA) dates back to 1948, when Mandel and Metais found it in the sera of cancer patients [...]
Nagy B.
europepmc +5 more sources
Technical and Methodological Aspects of Cell-Free Nucleic Acids Analyzes. [PDF]
Int J Mol Sci, 2020 Analyzes of cell-free nucleic acids (cfNAs) have shown huge potential in many biomedical applications, gradually entering several fields of research and everyday clinical care. Many biological properties of cfNAs can be informative to gain deeper insights into the function of the organism, such as their different types (DNA, RNAs) and subtypes (gDNA ...
Pös Z +8 more
europepmc +4 more sources
Circulating cell-free nucleic acids: characteristics and applications. [PDF]
Eur J Hum Genet, 2018 Liquid biopsy is becoming a very popular sample obtaining procedure, replacing the invasive sampling methods for the diagnostic protocols. The advantages of this method include the possibility to isolate cell-free nucleic acids (cfNAs) for diagnostic or screening purposes.
Pös O, Biró O, Szemes T, Nagy B.
europepmc +4 more sources
Liquid Biopsy as a Method for Minimally Invasive Diagnosis of Thyroid Cancer [PDF]
Клиническая практика, 2023 Thyroid cancer is the 9th most common cancer in the world. The five-year survival rate for this disease is over 98%. However, in some patients there are cases of rapidly progressive treatment-resistant cancer that cannot be differed from poor-invasive ...
Tagir I. Rakhmatullin +3 more
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Cell-Free Nucleic Acids and their Emerging Role in the Pathogenesis and Clinical Management of Inflammatory Bowel Disease. [PDF]
Int J Mol Sci, 2019 Kubiritova Z, Radvanszky J, Gardlik R.
europepmc +2 more sources
Cell-free fetal nucleic acids in amniotic fluid [PDF]
Human Reproduction Update, 2010 Research into cell-free fetal (cff) nucleic acids has primarily focused on maternal plasma; however, cff DNA and RNA are also detectable in other body fluids such as amniotic fluid (AF). In AF, cff DNA is present in much greater concentrations than in maternal plasma and represents a pure fetal sample uncontaminated by maternal- and trophoblast-derived
L, Hui, D W, Bianchi
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