Results 21 to 30 of about 246,410 (137)
Cell-free fetal nucleic acids in amniotic fluid [PDF]
Research into cell-free fetal (cff) nucleic acids has primarily focused on maternal plasma; however, cff DNA and RNA are also detectable in other body fluids such as amniotic fluid (AF). In AF, cff DNA is present in much greater concentrations than in maternal plasma and represents a pure fetal sample uncontaminated by maternal- and trophoblast-derived
L, Hui, D W, Bianchi
openaire +2 more sources
Wall-less bacteria are broadly distributed in diverse habitats. They evolved from a common ancestor within the Firmicutes phylum through reductive evolution.
Rikuan Zheng +4 more
doaj +1 more source
Circulating free nucleic acids; cell free DNA and circulating micro-RNA, are found in the plasma of patients with hematologic and solid malignancies at levels higher than that of healthy individuals.
Jay Hocking +3 more
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Oxidative stress, inflammation, and amyloid-β are Alzheimer’s disease (AD) hallmarks that cause each other and other AD hallmarks. Most amyloid-β-lowering, antioxidant, anti-inflammatory, and antimicrobial AD clinical trials failed; none stopped or ...
Owen Davis Sanders
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Plasma GBP2 promoter methylation is associated with advanced stages in breast cancer [PDF]
Blood methylated cell-free DNA (cfDNA) as a minimally invasive cancer biomarker has great importance in cancer management. Guanylate binding protein 2 (GBP2) has been considered as a possible controlling factor in tumor development.
Farzaneh Rahvar +2 more
doaj +1 more source
Pre-analytical issues in liquid biopsy – where do we stand?
It is well documented that in the chain from sample to the result in a clinical laboratory, the pre-analytical phase is the weakest and most vulnerable link. This also holds for the use and analysis of extracellular nucleic acids.
Fleischhacker Michael, Schmidt Bernd
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The effect of prostaglandins on protein and nucleic acid synthesis in a cell-free system [PDF]
T6S EFFECT OF PROSTAGLAI~INS ON PROTEIN AND NDCLEIC ACID SYNTHESIS IN A CELL-FREE SYSTEM R. W. Ruddon* and J. M. Johnson Department of Pharmacology, The pniversity of Michigan Medical School Ann Arbor, Michigan (Received 20 February 1967 ; in final form 13 March 1967) THE prostaglandins are a family of hydroxy unsaturated C20 fatty acids which have ...
Ruddon, Raymond W., Johnson, J. M.
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Background Blood plasma, one of the most studied liquid biopsies, contains various molecules that have biomarker potential for cancer detection, including cell-free DNA (cfDNA) and cell-free RNA (cfRNA). As the vast majority of cell-free nucleic acids in
Jill Deleu +10 more
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Circulating nucleic acids in the plasma and serum as potential biomarkers in neurological disorders [PDF]
Neurological diseases are responsible for approximately 6.8 million deaths every year. They affect up to 1 billion people worldwide and cause significant disability and reduced quality of life.
D.C.F. Bruno +7 more
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Urine holds great promise as a non-invasive sampling method for molecular diagnostics. The cell-free nucleic acids of urine however are small, labile, and difficult to purify.
Kayvan Zainabadi +3 more
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