Results 31 to 40 of about 246,410 (137)

TLR and NKG2D signaling pathways mediate CS-induced pulmonary pathologies. [PDF]

PLoS ONE, 2013
Long-term exposure to cigarette smoke (CS) can have deleterious effects on lung epithelial cells including cell death and the initiation of inflammatory responses.
Brian W Wortham, Bryan L Eppert, Jennifer L Flury, Sara Morgado Garcia, Michael T Borchers   +4 more
doaj   +1 more source

Cell-free nucleic acid patterns in disease prediction and monitoring—hype or hope? [PDF]

EPMA Journal, 2020
AbstractInterest in the use of cell-free nucleic acids (CFNAs) as clinical non-invasive biomarker panels for prediction and prevention of multiple diseases has greatly increased over the last decade. Indeed, circulating CFNAs are attributable to many physiological and pathological processes such as imbalanced stress conditions, physical activities ...
Crigna, Adriana Torres, Samec, Marek, Koklesova, Lenka, Liskova, Alena, Giordano, Frank A., Kubatka, Peter, Golubnitschaja, Olga   +6 more
openaire   +2 more sources

Evaluation of circulating cell-free nucleic acids in plasma as biomarkers of laryngeal cancer [PDF]

Cellular, Molecular and Biomedical Reports
It has been aimed to compare the level of cell-free nucleic acids (DNA, RNA, and miRNA) concentrations in laryngeal cancer patients with the control group composed of healthy individuals. It has been utilized 46 patients with laryngeal carcinoma who were
Basak Yavuz, Ozge Cil, Akin Cayir
doaj   +1 more source

Cardiolipin-Based Lipopolyplex Platform for the Delivery of Diverse Nucleic Acids into Gram-Negative Bacteria

Pharmaceuticals, 2019
Antibiotic resistance is a growing public health concern. Because only a few novel classes of antibiotics have been developed in the last 40 years, such as the class of oxazolidinones, new antibacterial strategies are urgently needed (Coates, A.R. et al.,
Federico Perche, Tony Le Gall, Tristan Montier, Chantal Pichon, Jean-Marc Malinge   +4 more
doaj   +1 more source

Cancer type classification using plasma cell-free RNAs derived from human and microbes

eLife, 2022
The utility of cell-free nucleic acids in monitoring cancer has been recognized by both scientists and clinicians. In addition to human transcripts, a fraction of cell-free nucleic acids in human plasma were proven to be derived from microbes and ...
Shanwen Chen, Yunfan Jin, Siqi Wang, Shaozhen Xing, Yingchao Wu, Yuhuan Tao, Yongchen Ma, Shuai Zuo, Xiaofan Liu, Yichen Hu, Hongyan Chen, Yuandeng Luo, Feng Xia, Chuanming Xie, Jianhua Yin, Xin Wang, Zhihua Liu, Ning Zhang, Zhenjiang Zech Xu, Zhi John Lu, Pengyuan Wang   +20 more
doaj   +1 more source

Cell-free Fetal Nucleic Acid Identifier Markers in Maternal Circulation

Advanced Biomedical Research, 2017
From the discovery of cell-free fetal (cff)-DNA in 1997 so far, many studies have been performed on various aspects of cff-nucleic acid. It is undoubted that currently, invasive prenatal diagnosis progresses to the noninvasive test. However, there are many problems.
Mahboubeh Ramezanzadeh, Sharifeh Khosravi, Rasoul Salehi   +2 more
openaire   +3 more sources

Diagnostic potential of cell-free fetal nucleic acids in predicting pregnancy complications: A systematic review and meta-analysis on trisomy, pre-eclampsia, and gestational diabetes

International Journal of Reproductive BioMedicine
Background: Recent studies reveal an association between increased cell-free fetal (cff) nucleic acid in maternal blood and pregnancy challenges like loss, pre-eclampsia, growth restriction, and preterm labor.
Jiut Ram Keshari, Pritam Prakash, Seema Rani Sinha, Prem Prakash, Kirti Rani, Tarique Aziz, Shaily Shilpa   +6 more
doaj   +1 more source

Opportunities and challenges of circulating biomarkers in neuroblastoma [PDF]

Open Biology, 2019
Molecular analysis of nucleic acid and protein biomarkers is becoming increasingly common in paediatric oncology for diagnosis, risk stratification and molecularly targeted therapeutics. However, many current and emerging biomarkers are based on analysis
Ricky M. Trigg, Jacqui A. Shaw, Suzanne D. Turner   +2 more
doaj   +1 more source

Recent advances in cancer-associated circulating cell-free nucleic acids

Zhongguo aizheng zazhi, 2014
Circulating cell-free nucleic acids are defined as extracellular DNAs or RNAs in blood with physiological or pathological origins. Previous studies showed that the concentration of cell-free nucleic acids in the blood of cancer patients is significantly ...
邢星, 刘勇, 孙勇, 周鑫, 胡超苏   +4 more
doaj  

Cell-Free Circulating Nucleic Acids as Early Biomarkers for NAFLD and NAFLD-Associated Disorders

Frontiers in Physiology, 2018
Non-alcoholic fatty liver disease (NAFLD) is the worldwide most common cause of chronic liver pathology, which prevalence strongly correlates with the increasing incidence of diabetes, obesity and metabolic syndrome in the general population.
Andrey Turchinovich, Andrey Turchinovich, Ancha Baranova, Ancha Baranova, Ancha Baranova, Oksana Drapkina, Alexander Tonevitsky, Alexander Tonevitsky, Alexander Tonevitsky   +8 more
doaj   +1 more source