Results 101 to 110 of about 371,071 (337)

Dual Receptor Recognizing Cell Penetrating Peptide for Selective Targeting, Efficient Intratumoral Diffusion and Synthesized Anti-Glioma Therapy

Theranostics, 2016
Cell penetrating peptides (CPPs) were widely used for drug delivery to tumor. However, the nonselective in vivo penetration greatly limited the application of CPPs-mediated drug delivery systems.
Yayuan Liu, Ling Mei, Chao-qun Xu, Qianwen Yu, Kairong Shi, Li Zhang, Yang Wang, Qianyu Zhang, Huile Gao, Zhirong Zhang, Qin He   +10 more
semanticscholar   +1 more source

Liquid Crystalline Inverted Lipid Phases and Reverse Micelles in Drug Delivery: From Molecular Design to Therapeutic Potential

Advanced Functional Materials, EarlyView.
Liquid crystalline inverted lipid phases and reverse micelles are self‐assembled lipid nanostructures that enhance the solubility, stability, and delivery of diverse therapeutics. This review integrates their physicochemical principles, formulation strategies, drug loading mechanisms, and biomedical applications, highlighting their growing ...
Numan Eczacioglu, Mulazim Hussain Asim, Soheil Haddadzadegan, Andreas Bernkop‐Schnürch   +3 more
wiley   +1 more source

Cell Penetrating Capacity and Internalization Mechanisms Used by the Synthetic Peptide CIGB-552 and Its Relationship with Tumor Cell Line Sensitivity

Molecules, 2018
CIGB-552 is a twenty-amino-acid novel synthetic peptide that has proven to be effective in reducing tumor size and increasing lifespan in tumor-bearing mice. Such capability is conferred by its cell-penetrating peptide character, which allows it to enter
Soledad Astrada, Julio Raúl Fernández Massó, Maribel G. Vallespí, Mariela Bollati-Fogolín   +3 more
doaj   +1 more source

The Role of Cell-Penetrating Peptide and Transferrin on Enhanced Delivery of Drug to Brain

International Journal of Molecular Sciences, 2016
The challenge of effectively delivering therapeutic agents to brain has led to an entire field of active research devoted to overcome the blood brain barrier (BBB) and efficiently deliver drugs to brain.
Gitanjali Sharma, Sushant Lakkadwala, A. Modgil, Jagdish Singh   +3 more
semanticscholar   +1 more source

Cationic Cell-Penetrating Peptides Traverse Membranes through Lysis or Direct Translocation Pathways [PDF]

, 2020
Jason Warner, Dong An, Benjamin S. Stratton, Ben O’Shaughnessy   +3 more
openalex   +1 more source

Real‐Time, Label‐Free Monitoring of Cell Behavior on a Bioelectronic Scaffold

Advanced Functional Materials, EarlyView.
A bioelectronic nanofibrous scaffold is introduced that supports cell growth while enabling real‐time, label‐free monitoring of cellular behavior through impedance measurements. The system correlates electrical signals with cell viability and surface coverage, offering an integrated platform for studying dynamic biological processes and advancing next ...
Dana Cohen‐Gerassi, Offir Loboda, Aakash Jog, Or Messer, Dor Aaron Goldstein, Tomer Reuveni, Moran Aviv, Amit Sitt, Yosi Shacham‐Diamand, Maxim Sokol, Lihi Adler‐Abramovich   +10 more
wiley   +1 more source

Charge converting nanostructured lipid carriers containing a cell-penetrating peptide for enhanced cellular uptake

, 2022
Patrick Knoll, Nikolas Hörmann, Nguyet‐Minh Nguyen Le, Richard Wibel, Ronald Gust, Andreas Bernkop‐Schnürch   +5 more
openalex   +2 more sources

Engineering a Sonotherapeutic RBC Membrane‐Derived Nanoparticle Platform for the Treatment of Liver Cancer

Advanced Functional Materials, EarlyView.
Herein, an RBC membrane‐derived nanoparticle (CMN‐ICG) is engineered to efficiently deliver a sonosensitizing agent, indocyanine green (ICG), for sonotherapy of hepatocellular carcinoma (HCC). CMN‐ICG exhibits excellent cytocompatibility, significantly enhances hepatocyte uptake, and produces excessive reactive oxygen species (ROS) upon ultrasound ...
Alap Ali Zahid, Aishik Chakraborty, Wei Luo, Juhi Bora, John Joseph Kelly, John Andrew Ronald, Arghya Paul   +6 more
wiley   +1 more source

Functional Peptide-Based Biomaterials for Pharmaceutical Application: Sequences, Mechanisms, and Optimization Strategies

Journal of Functional Biomaterials
Peptide-based biomaterials have emerged as versatile tools for pharmaceutical drug delivery due to their biocompatibility and tunable sequences, yet a comprehensive overview of their categories, mechanisms, and optimization strategies remains lacking to ...
Dedong Yu, Nari Han, Hyejeong Son, Sun Jo Kim, Seho Kweon   +4 more
doaj   +1 more source

Topical Delivery of Protein and Peptide Using Novel Cell Penetrating Peptide IMT-P8

Scientific Reports, 2016
Skin, being the largest organ of the body, is an important site for drug administration. However, most of the drugs have poor permeability and thus drug delivery through the skin is very challenging.
A. Gautam, J. Nanda, Jesse S. Samuel, M. Kumari, Priyanka Priyanka, Gursimran Bedi, S. Nath, G. Mittal, Neeraj Khatri, Gajendra P. Raghava   +9 more
semanticscholar   +1 more source