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Cell Penetrating Peptides [PDF]
, 2022 Classes of Cell-Penetrating Peptides. Mechanisms of Cell Penetration, Interactions of Cell-Penetrating Peptides with Plasma Membranes and Lipid Models. Applications of Cell-Penetrating Peptides.
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Cell Penetrating Peptides: Classification, Mechanisms, Methods of Study, and Applications
ChemMedChem, 2023 Cell‐penetrating peptides (CPPs) encompass a class of peptides that possess the remarkable ability to cross cell membranes and deliver various types of cargoes, including drugs, nucleic acids, and proteins, into cells.
A. Gori +4 more
semanticscholar +1 more source
Cell-Penetrating Milk-Derived Peptides with a Non-Inflammatory Profile
Molecules, 2023 Milk-derived peptides are known to confer anti-inflammatory effects. We hypothesised that milk-derived cell-penetrating peptides might modulate inflammation in useful ways.
Clement Agoni +8 more
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The role of cell‐penetrating peptides in potential anti‐cancer therapy
Clinical and Translational Medicine, 2022 Due to the complex physiological structure, microenvironment and multiple physiological barriers, traditional anti‐cancer drugs are severely restricted from reaching the tumour site.
Meiling Zhou +9 more
semanticscholar +1 more source
Membrane Internalization Mechanisms and Design Strategies of Arginine-Rich Cell-Penetrating Peptides
International Journal of Molecular Sciences, 2022 Cell-penetrating peptides (CPPs) have been discovered to deliver chemical drugs, nucleic acids, and macromolecules to permeate cell membranes, creating a novel route for exogenous substances to enter cells.
Minglu Hao, Lei Zhang, Pu Chen
semanticscholar +1 more source
Designed Multifunctional Peptides for Intracellular Targets
Antibiotics, 2022 Nature’s way for bioactive peptides is to provide them with several related functions and the ability to cooperate in performing their job. Natural cell-penetrating peptides (CPP), such as penetratins, inspired the design of multifunctional constructs ...
Davor Juretić
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Nature Communications, 2021 Cytosolic transport is an essential requirement but a major obstacle to efficient delivery of therapeutic peptides, proteins and nucleic acids. Current understanding of cytosolic delivery mechanisms remains limited due to a significant number of ...
S. L. Teo +5 more
semanticscholar +1 more source
Cell-Penetrating Peptides (CPPs) as Therapeutic and Diagnostic Agents for Cancer
Cancers, 2022 Simple Summary Crossing biological barriers is often required for drug delivery. Cell-penetrating peptides (CPPs) are short strands of amino acids that have been widely used as a delivery vehicle to overcome barriers for various applications. This review
Ryan A. Bottens, Tohru Yamada
semanticscholar +1 more source
Cell-Penetrating Peptide–Bismuth Bicycles
Angewandte Chemie, 2023 Cell-penetrating peptides (CPPs) play a significant role in the delivery of cargos into human cells for a wide range of therapeutic and diagnostic applications. We disclose the first CPPs based on peptide–bismuth bicycles, which can be readily obtained from commercially available peptide precursors, making them highly accessible for a wide range of ...
Saan Voss +8 more
openaire +2 more sources
Prediction of cell penetrating peptides by support vector machines. [PDF]
PLoS Computational Biology, 2011 Cell penetrating peptides (CPPs) are those peptides that can transverse cell membranes to enter cells. Once inside the cell, different CPPs can localize to different cellular components and perform different roles.
William S Sanders +4 more
doaj +1 more source