Results 31 to 40 of about 395,472 (375)

Cell-Penetrating Peptides in Diagnosis and Treatment of Human Diseases: From Preclinical Research to Clinical Application

Frontiers in Pharmacology, 2020
Cell-penetrating peptides (CPPs) are short peptides (fewer than 30 amino acids) that have been predominantly used in basic and preclinical research during the last 30 years.
Jing Xie, Ye Bi, Huan Zhang, Shiyan Dong, Lesheng Teng, Robert J. Lee, Zhaogang Yang   +6 more
semanticscholar   +1 more source

Cell-Penetrating Peptides: Emerging Tools for mRNA Delivery

Pharmaceutics, 2021
Messenger RNAs (mRNAs) were previously shown to have great potential for preventive vaccination against infectious diseases and therapeutic applications in the treatment of cancers and genetic diseases.
Hidetomo Yokoo, M. Oba, S. Uchida
semanticscholar   +1 more source

Prediction of Cell-Penetrating Potential of Modified Peptides Containing Natural and Chemically Modified Residues

Frontiers in Microbiology, 2018
Designing drug delivery vehicles using cell-penetrating peptides is a hot area of research in the field of medicine. In the past, number of in silico methods have been developed for predicting cell-penetrating property of peptides containing natural ...
Vinod Kumar, Vinod Kumar, Piyush Agrawal, Piyush Agrawal, Rajesh Kumar, Rajesh Kumar, Sherry Bhalla, Salman Sadullah Usmani, Salman Sadullah Usmani, Grish C. Varshney, Gajendra P. S. Raghava, Gajendra P. S. Raghava   +11 more
doaj   +1 more source

Cell-penetrating peptides and their analogues as novel nanocarriers for drug delivery [PDF]

BioImpacts, 2015
Introduction: The impermeability of biological membranes is a major obstacle in drug delivery; however, some peptides have transition capabilities of biomembranes.
Samira Jafari, Solmaz Maleki Dizaj, khosro adibkia   +2 more
doaj   +1 more source

Synthesis and cellular penetration properties of new phosphonium based cationic amphiphilic peptides [PDF]

, 2018
A new category of phosphonium based cationic amphiphilic peptides has been developed and evaluated as potential antimicrobial peptides and cell penetrating peptides.
Gannon, Susan, Hezwani, Mohammed, Liskamp, Rob M.J., Pirvan, Alin, Postma, Tobias, Riehle, Mathis, Silva Nigenda, Ezequiel, Smith, Carol-Anne   +7 more
core   +1 more source

Applications of Cell-Penetrating Peptides for Tumor Targeting and Future Cancer Therapies

Pharmaceuticals, 2012
Cell-penetrating peptides provide a highly promising strategy for intracellular drug delivery. One relevant clinical application of cell-penetrating peptides is cancer therapeutics. Peptide based delivery could increase the uptake of drugs in tumor cells
Ülo Langel, Artita Srimanee, Jakob Regberg   +2 more
doaj   +1 more source

Nucleic acid delivery by cell-penetrating peptides [PDF]

Proceedings of the Estonian Academy of Sciences, 2023
Establishment of multiple novel mechanisms and applications of cell-penetrating peptides (CPP) has been demonstrated, leading to novel drug delivery systems.
Ülo Langel
doaj   +1 more source

New generation of cell‐penetrating peptides: Functionality and potential clinical application

Journal of Peptide Science, 2021
Cell‐penetrating peptides (CPPs) can transport various cargoes through membranes of live cells. Since the first generations of CPPs suffered from insufficient cell and tissue selectivity, stability against proteases, and escape from endosomes, a new ...
S. Reissmann, M. P. Filatova
semanticscholar   +1 more source

Cell-penetrating Peptides [PDF]

Journal of Biological Chemistry, 2003
The present invention discloses cell penetrating peptides and conjugates of a cell penetrating peptide and a cargo molecule.
Jean Philippe Richard, Kamran Melikov, Eric Vives, Corinne Ramos, Birgit Verbeure, Mike J. Gait, Leonid V. Chernomordik, Bernard Lebleu   +7 more
openaire   +1 more source

Cell-Penetrating Peptides Derived from Animal Venoms and Toxins

Toxins, 2021
Cell-penetrating peptides (CPPs) comprise a class of short polypeptides that possess the ability to selectively interact with the cytoplasmic membrane of certain cell types, translocate across plasma membranes and accumulate in the cell cytoplasm ...
G. Rádis-Baptista
semanticscholar   +1 more source