Results 41 to 50 of about 1,695,350 (286)

HDAC1/2 control mesothelium/ovarian cancer adhesive interactions impacting on Talin-1-α5β1-integrin-mediated actin cytoskeleton and extracellular matrix protein remodeling

Journal of Experimental & Clinical Cancer Research
Background Peritoneal metastasis, which accounts for 85% of all epithelial ovarian carcinoma (EOC) metastases, is a multistep process that requires the establishment of adhesive interactions between cancer cells and the peritoneal membrane ...
Michela Terri, Pilar Sandoval, Giulio Bontempi, Claudia Montaldo, Henar Tomero-Sanz, Valeria de Turris, Flavia Trionfetti, Lucía Pascual-Antón, Irene Clares-Pedrero, Cecilia Battistelli, Sergio Valente, Clemens Zwergel, Antonello Mai, Laura Rosanò, Miguel Ángel del Pozo, Miguel Sánchez-Álvarez, Carlos Cabañas, Marco Tripodi, Manuel López-Cabrera, Raffaele Strippoli   +19 more
doaj   +1 more source

Moment-based analysis of biochemical networks in a heterogeneous population of communicating cells

, 2019
Cells can utilize chemical communication to exchange information and coordinate their behavior in the presence of noise. Communication can reduce noise to shape a collective response, or amplify noise to generate distinct phenotypic subpopulations.
Gonzales, David T., Tang, T-Y Dora, Zechner, Christoph   +2 more
core   +1 more source

A Versatile, Portable Intravital Microscopy Platform for Studying Beta-cell Biology In Vivo [PDF]

, 2019
The pancreatic islet is a complex micro-organ containing numerous cell types, including endocrine, immune, and endothelial cells. The communication of these systems is lost upon isolation of the islets, and therefore the pathogenesis of diabetes can only
Conteh, Abass M., Day, Richard N., Dunn, Kenneth W., Kamocka, Malgorzata M., Linnemann, Amelia K., Martinez, Michelle M., Mirmira, Raghavendra G., Orr, Kara S., Piñeros, Annie R., Reissaus, Christopher A., Tersey, Sarah A., Twigg, Ashley N.   +11 more
core   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Cell-to-Cell Communication during Lateral Root Development [PDF]

Molecular Plant, 2014
Cell-to-cell communication plays an important role in coordinating development and specifying cell fate in all multicellular organisms. In plants, wherein cells are immobilized and trapped within a bodice of cellulosic cell walls, exchange of positional information required for normal organogenesis has recently become the object of a growing area of ...
Yue, Kun, Beeckman, Tom
openaire   +2 more sources

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source

Exosomal miRNA: an alternative mediator of cell-to-cell communication

ExRNA, 2019
Mounting evidence show that miRNAs are loaded into exosomes and secreted by almost all types of cells. miRNAs are selectively sorted into exosomes, and transferred to recipient cells, where they manipulate cell function.
Jing Li, Xiaohong Jiang, Kehui Wang
doaj   +1 more source

A Gene Expression Clustering Method to Extraction of Cell-to-Cell Biological Communication

Inteligencia Artificial, 2022
Graph-based clustering identification is a practical method to detect the communication between nodes in complex networks that has obtained considerable comments.
Hui Wang, Yan Sha, Dan Wang, Hamed Nazari   +3 more
doaj   +1 more source

Exercise-Derived Microvesicles: A Review of the Literature [PDF]

, 2018
Initially suggested as simple cell debris, cell-derived microvesicles (MVs) have now gained acceptance as recognized players in cellular communication and physiology.
Mourot, Laurent, Rakobowchuk, Mark, Wilhelm, Eurico N.   +2 more
core   +2 more sources

Inpatient Food Insecurity and Pediatric Hematology Oncology Hospitalization Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Children with cancer and blood disorders are at risk for food insecurity (FI). We aimed to describe the association of inpatient food insecurity (IFI) and hospitalization outcomes among patients admitted to the pediatric hematology oncology service. Of 325 caregivers screened for IFI, 60 (18.6%) screened positive.
Joanna M. Robles, Greg Russell, Leila H. DeWitt, Kimberly Montez, Callie L. Brown   +4 more
wiley   +1 more source