Results 51 to 60 of about 1,695,350 (286)

Trash or Treasure: extracellular microRNAs and cell-to-cell communication

open access: yesFrontiers in Genetics, 2013
Circulating RNAs in human body fluids are promising candidates for diagnostic purposes. However, the biological significance of circulating RNAs remains elusive.
Nobuyoshi eKosaka   +5 more
doaj   +1 more source

Extracellular Vesicles in the Development of the Non-Alcoholic Fatty Liver Disease: An Update

open access: yesBiomolecules, 2020
Non-alcoholic fatty liver disease (NAFLD) is a broad spectrum of liver damage disease from a simple fatty liver (steatosis) to more severe liver conditions such as non-alcoholic steatohepatitis (NASH), fibrosis, and cirrhosis. Extracellular vesicles (EVs)
Vicneswarry Dorairaj   +3 more
doaj   +1 more source

Exosomes and Exosomal miRNA in Respiratory Diseases [PDF]

open access: yes, 2016
Exosomes are nanosized vesicles released from every cell in the body including those in the respiratory tract and lungs. They are found in most body fluids and contain a number of different biomolecules including proteins, lipids, and both mRNA and ...
Adcock, IM   +5 more
core   +4 more sources

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider   +4 more
wiley   +1 more source

Programmable Enzymatic Reaction Network in Artificial Cell‐Like Polymersomes

open access: yesAdvanced Science
The ability to precisely control in vitro enzymatic reactions in synthetic cells plays a crucial role in the bottom‐up design of artificial cell models that can recapitulate the key cellular features and functions such as metabolism. However, integration
Hanjin Seo, Hyomin Lee
doaj   +1 more source

On the Performance Gain of NOMA over OMA in Uplink Communication Systems

open access: yes, 2019
In this paper, we investigate and reveal the ergodic sum-rate gain (ESG) of non-orthogonal multiple access (NOMA) over orthogonal multiple access (OMA) in uplink cellular communication systems. A base station equipped with a single-antenna, with multiple
Hanzo, Lajos   +4 more
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The role of vegetative cell fusions in the development and asexual reproduction of the wheat fungal pathogen Zymoseptoria tritici

open access: yesBMC Biology, 2020
Background The ability of fungal cells to undergo cell-to-cell communication and anastomosis, the process of vegetative hyphal fusion, allows them to maximize their overall fitness.
Carolina Sardinha Francisco   +2 more
doaj   +1 more source

The impact of cellular characteristics on the evolution of shape homeostasis

open access: yes, 2017
The importance of individual cells in a developing multicellular organism is well known but precisely how the individual cellular characteristics of those cells collectively drive the emergence of robust, homeostatic structures is less well understood ...
Anderson, Alexander R. A.   +2 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

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