Results 61 to 70 of about 1,820,621 (315)

The role of vegetative cell fusions in the development and asexual reproduction of the wheat fungal pathogen Zymoseptoria tritici

BMC Biology, 2020
Background The ability of fungal cells to undergo cell-to-cell communication and anastomosis, the process of vegetative hyphal fusion, allows them to maximize their overall fitness.
Carolina Sardinha Francisco, Maria Manuela Zwyssig, Javier Palma-Guerrero   +2 more
doaj   +1 more source

A Versatile, Portable Intravital Microscopy Platform for Studying Beta-cell Biology In Vivo [PDF]

, 2019
The pancreatic islet is a complex micro-organ containing numerous cell types, including endocrine, immune, and endothelial cells. The communication of these systems is lost upon isolation of the islets, and therefore the pathogenesis of diabetes can only
Conteh, Abass M., Day, Richard N., Dunn, Kenneth W., Kamocka, Malgorzata M., Linnemann, Amelia K., Martinez, Michelle M., Mirmira, Raghavendra G., Orr, Kara S., Piñeros, Annie R., Reissaus, Christopher A., Tersey, Sarah A., Twigg, Ashley N.   +11 more
core   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

E-cadherin and cell adhesion: a role in architecture and function in the pancreatic islet [PDF]

, 2007
Background/Aims: The efficient secretion of insulin from beta-cells requires extensive intra-islet communication. The cell surface adhesion protein epithelial (E)-cadherin (ECAD) establishes and maintains epithelial tissues such as the islets of ...
Bamji SX, Braga VMM, Brereton HC, Cabrera O, Collares-Buzato CB, Dahl U, Gareth J. Rogers, Gey GO, Gray E, Hellman B, Hills CE, Hodgkin MN, Kanno Y, Matsuda T, Matthew N. Hodgkin, Musil LS, Paul E. Squires, Piccoli G, Shih DQ, Squires PE, Squires PE, Woodfield RJ   +21 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Programmable Enzymatic Reaction Network in Artificial Cell‐Like Polymersomes

Advanced Science
The ability to precisely control in vitro enzymatic reactions in synthetic cells plays a crucial role in the bottom‐up design of artificial cell models that can recapitulate the key cellular features and functions such as metabolism. However, integration
Hanjin Seo, Hyomin Lee
doaj   +1 more source

Exercise-Derived Microvesicles: A Review of the Literature [PDF]

, 2018
Initially suggested as simple cell debris, cell-derived microvesicles (MVs) have now gained acceptance as recognized players in cellular communication and physiology.
Mourot, Laurent, Rakobowchuk, Mark, Wilhelm, Eurico N.   +2 more
core   +2 more sources

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Melatonin and TGF-β-Mediated Release of Extracellular Vesicles

Metabolites, 2023
The immune system, unlike other systems, must be flexible and able to “adapt” to fully cope with lurking dangers. The transition from intracorporeal balance to homeostasis disruption is associated with activation of inflammatory signaling pathways, which
Klaudia Piekarska, Klaudia Bonowicz, Alina Grzanka, Łukasz M. Jaworski, Russel J. Reiter, Andrzej T. Slominski, Kerstin Steinbrink, Konrad Kleszczyński, Maciej Gagat   +8 more
doaj   +1 more source

Exosomes and Exosomal miRNA in Respiratory Diseases [PDF]

, 2016
Exosomes are nanosized vesicles released from every cell in the body including those in the respiratory tract and lungs. They are found in most body fluids and contain a number of different biomolecules including proteins, lipids, and both mRNA and ...
Adcock, IM, Alipoor, SD, Garssen, J, Mirsaeidi, M, Mortaz, E, Movassaghi, M   +5 more
core   +4 more sources