Results 121 to 130 of about 18,635,088 (264)

Usefulness of Mesenchymal Cell Lines for Bone and Cartilage Regeneration Research [PDF]

, 2019
María Piñeiro-Ramil, Clara Sanjurjo‐Rodríguez, Rocío Castro-Viñuelas, Silvia Rodríguez-Fernández, Isaac Fuentes‐Boquete, Francisco J. Blanco, Silvia Díaz‐Prado   +6 more
openalex   +1 more source

Adipose-derived stem cells inhibit dermal fibroblast growth and induce apoptosis in keloids through the arachidonic acid-derived cyclooxygenase-2/prostaglandin E2 cascade by paracrine

, 2021
Jinxiu Yang, Shiyi Li, Leren He, Minliang Chen   +3 more
openalex   +1 more source

Natural killer cell levels in adults living with type 2 diabetes: a systematic review and meta-analysis of clinical studies [PDF]

, 2020
Vuyolwethu Mxinwa, Phiwayinkosi V. Dludla, Tawanda M. Nyambuya, Kabelo Mokgalaboni, Sithandiwe E. Mazibuko-Mbeje, Bongani B. Nkambule   +5 more
openalex   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Role of Oncogenic K-Ras in Cancer Stem Cell Activation by Aberrant Wnt/β-Catenin Signaling

, 2014
Byoung-San Moon, Woo-Jeong Jeong, Jieun Park, Tae Il Kim, Do Sik Min, Kang‐Yell Choi   +5 more
openalex   +2 more sources

MiR-34a affects G2 arrest in prostate cancer PC3 cells via Wnt pathway and inhibits cell growth and migration.

, 2020
Bo Dong, Xu Gc, Liu St, Liu T, Bin Geng
openalex   +2 more sources

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Proteomic analysis of mitochondrial biogenesis in cardiomyocytes differentiated from human induced pluripotent stem cells

, 2020
Sundararajan Venkatesh, Erdene Baljinnyam, Mingming Tong, Toshihide Kashihara, Yan Lin, Tong Liu, Hong Li, Lai‐Hua Xie, Michinari Nakamura, Shinichi Oka, Carolyn K. Suzuki, Diego Fraidenraich, Junichi Sadoshima   +12 more
openalex   +2 more sources

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source