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Programming multicellular assembly with synthetic cell adhesion molecules. [PDF]
Nature, 2023 Synthetic cell adhesion molecules yield customized cell–cell interactions with adhesion properties that are similar to native interactions, and offer abilities for cell and tissue engineering and for systematically studying multicellular organization ...
Stevens AJ +10 more
europepmc +2 more sources
Elevated Expression of Serum Endothelial Cell Adhesion Molecules in COVID-19 Patients
Journal of Infectious Diseases, 2020 In a retrospective study of 39 COVID-19 patients and 32 control participants in China, we collected clinical data and examined the expression of endothelial cell adhesion molecules by enzyme-linked immunosorbent assays.
Ming Tong +8 more
semanticscholar +1 more source
Cell Adhesion Molecules and Their Roles and Regulation in the Immune and Tumor Microenvironment
Frontiers in Immunology, 2019 The immune system and cancer have a complex relationship with the immune system playing a dual role in tumor development. The effector cells of the immune system can recognize and kill malignant cells while immune system-mediated inflammation can also ...
Heidi Harjunpää +3 more
semanticscholar +1 more source
Criticality in Cell Adhesion [PDF]
Phys. Rev. X 11, 031067 (2021), 2020 We illuminate the many-body effects underlying the structure, formation, and dissolution of cellular adhesion domains in the presence and absence of forces. We consider mixed Glauber-Kawasaki dynamics of a two-dimensional model of nearest-neighbor interacting adhesion bonds with intrinsic binding-affinity under the action of a shared pulling or pushing
arxiv +1 more source
Endothelial microRNAs regulating the NF‐κB pathway and cell adhesion molecules during inflammation
The FASEB Journal, 2018 The surface of endothelial cells is covered with cell adhesion molecules, including E‐selectin, intercellula adhesion molecule 1 (ICAM‐1), and vascular cell adhesion molecule 1 (VCAM‐ 1), that mediate the adhesion an extravasation of leukocytes and play ...
L. Zhong, M. J. Simard, J. Huot
semanticscholar +1 more source
The Many Roles of Cell Adhesion Molecules in Hepatic Fibrosis
Cells, 2019 Fibrogenesis is a progressive scarring event resulting from disrupted regular wound healing due to repeated tissue injury and can end in organ failure, like in liver cirrhosis.
E. Hintermann, U. Christen
semanticscholar +1 more source
Collective Cell Movement in Cell-Scale Tension Gradient on Tissue Interface [PDF]
, 2021 In this paper, we examine the emergence of cell flow induced by a tension gradient on a tissue interface as in the case of the Marangoni flow on liquid interface. We consider the molecule density polarity of the heterophilic adhesion between tissues as the origin of the tension gradient.
arxiv +1 more source
Science Translational Medicine, 2016 Nanoparticles deliver siRNA for multigene silencing of endothelial cell adhesion molecules, which dampens leukocyte recruitment in atherosclerosis and myocardial infarction in mice. Knocking down adhesion, knocking out inflammation Cells that are central
H. Sager +22 more
semanticscholar +1 more source
Cell adhesion in cancer: Beyond the migration of single cells
Journal of Biological Chemistry, 2020 Homeostasis in healthy tissues strongly relies on cell-to-cell adhesion and cell-to-extracellular matrix interactions. For instance, normal epithelial cells maintain tissue structure by adhering to each other and to the extracellular matrix. The proteins
M. Janiszewska, M. C. Primi, T. Izard
semanticscholar +1 more source
Experimental biology and medicine, 2017 Atherosclerosis is a leading cause of death worldwide; in addition to lipid dysfunction, chronic arterial wall inflammation is a key component of atherosclerosis. Techniques that target cell adhesion molecules, which are overexpressed during inflammation,
Khosrow Khodabandehlou +4 more
semanticscholar +1 more source