Results 1 to 10 of about 17,268 (265)
Cell Adhesion Molecules in Fibrotic Diseases
Biomedicines, 2023 Mechanisms underlying the pathogenesis of tissue fibrosis remain incompletely understood. Emerging evidence suggests that cell adhesion molecules (CAMs) are critical in fibrotic progression in many organs, including lung, kidney, skin, and liver.
Qianjiang Hu +5 more
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Circulating LPS from gut microbiota leverages stenosis-induced deep vein thrombosis in mice
Thrombosis Journal, 2023 Objective and design An accumulating body of evidence has shown that gut microbiota is involved in regulating inflammation; however, it remains undetermined if and how gut microbiota plays an important role in modulating deep venous thrombosis (DVT ...
Cheng Liu +9 more
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Stick around: Cell–Cell Adhesion Molecules during Neocortical Development
Cells, 2021 The neocortex is an exquisitely organized structure achieved through complex cellular processes from the generation of neural cells to their integration into cortical circuits after complex migration processes. During this long journey, neural cells need
David de Agustín-Durán +3 more
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Endothelial Cell Adhesion Molecules- (un)Attainable Targets for Nanomedicines
Frontiers in Medical Technology, 2022 Endothelial cell adhesion molecules have long been proposed as promising targets in many pathologies. Despite promising preclinical data, several efforts to develop small molecule inhibitors or monoclonal antibodies (mAbs) against cell adhesion molecules
Nenad Milošević +2 more
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Cell Adhesion Molecules in Normal Skin and Melanoma
Biomolecules, 2021 Cell adhesion molecules (CAMs) of the cadherin, integrin, immunoglobulin, and selectin protein families are indispensable for the formation and maintenance of multicellular tissues, especially epithelia.
Cian D’Arcy, Christina Kiel
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Sharpin suppresses β1-integrin activation by complexing with the β1 tail and kindlin-1
Cell Communication and Signaling, 2019 Background Previously sharpin has been identified as an endogenous inhibitor of β1-integrin activation by directly binding to a conserved region in the cytoplasmic tails (CTs) of the integrin β1-associated α subunits. Methods Here we employed biochemical
Juan Gao +12 more
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Increased expression of cell adhesion molecules in myofasciitis
Frontiers in Neurology, 2023 BackgroundMyofasciitis is a heterogeneous group of diseases pathologically characterized by inflammatory cell infiltration into the fascia. Endothelial activation plays a critical role in the pathogenesis of the inflammatory response.
Xue Ma +6 more
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Re: Role of Telomeres and Telomerase in Cancer
Journal of Urological Surgery, 2016 The most important difference between cancer and normall cells is the ability to continuous proliferation. This activation works due to telomeres and telomerase enzyme.
Shay JW, Wright WE
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Cell adhesion molecules in the pathogenesis of the schizophrenia [PDF]
Folia Medica, 2023 The causes of schizophrenia remain obscure and complex to identify. Alterations in dopaminergic and serotonergic neurotransmission are, to date, the primary pharmacological targets in treatment.
Antonino Messina +4 more
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The importance of selected cell adhesion molecules in thyroid cancer
Journal of Education, Health and Sport, 2018 Thyroid cancer is the most common malignant tumour of the endocrine system. It accounts for ca. 2% of all malignant tumours in the world, ranking it 16th in the overall classification. Its most common histology type is the papillary carcinoma originating
Magdalena Urbańczuk +5 more
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