Results 111 to 120 of about 14,856,340 (397)

Quantitative proteomics and lipidomics of TFG-deficient B cells provide insights into mechanisms of autophagic flux and plasma cell biology [PDF]

, 2022
Tobit Steinmetz, Lena Reimann, Sebastian Schulz, Sophia Urbanczyk, Jana Thomas, Ann-Kathrin Himmelreich, Florian Golombek, Kathrin Castiglione, Susanne Brodesser, Bettina Warscheid, Dirk Mielenz   +10 more
openalex   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Editorial, Seminars in Cell & Developmental Biology [PDF]

, 2009
It is a pleasure to introduce this special edition of Cell and Development Biology dedicated to the field and application of Biosensors. This edition comprises seven reviews covering the most active research areas where we believe some of the most ...
Davis, Frank, Higson, Seamus P. J.
core   +1 more source

Intrinsically disordered regions and RNA binding domains contribute to protein enrichment in biomolecular condensates in Xenopus oocytes

Scientific Reports
Proteins containing both intrinsically disordered regions (IDRs) and RNA binding domains (RBDs) can phase separate in vitro, forming bodies similar to cellular biomolecular condensates.
Liam C. O’Connell, Victoria Johnson, Jessica P. Otis, Anika K. Hutton, Anastasia C. Murthy, Mark C. Liang, Szu-Huan Wang, Nicolas L. Fawzi, Kimberly L. Mowry   +8 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

CRISPR for Bio-Art? [PDF]

, 2018
Es el resumen de mi ponencia oral (seleccionada entre todas las propuestas recibidas de todo el mundo, siendo una de las 12 únicas comunicaciones orales y la única con representante español en dicho Simposio).This communication will explain the ...
Medina, Miguel Ángel
core  

Future Needs in Mast Cell Biology. [PDF]

, 2019
The pathophysiological roles of mast cells are still not fully understood, over 140 years since their description by Paul Ehrlich in 1878. Initial studies have attempted to identify distinct "subpopulations" of mast cells based on a relatively small ...
de Paulis, Amato, Galli, Stephen J, Marone, Gianni, Varricchi, Gilda   +3 more
core   +2 more sources

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

A homozygous genome‐edited Sept2‐EGFP fibroblast cell line [PDF]

, 2019
Septins are a conserved, essential family of GTPases that interact with actin, microtubules, and membranes and form scaffolds and diffusion barriers in cells. Several of the 13 known mammalian septins assemble into nonpolar, multimeric complexes that can
Banko, Monika, Ewers, Helge, Heyd, Florian, Mucha‐Kruczynska, Iwona, Weise, Christoph   +4 more
core   +1 more source

Hepatocyte-Targeted Epicatechin Nanoparticles Promote Autophagy and Enhance Mitochondrial Function in Metabolic Dysfunction-Associated Steatotic Liver Disease

International Journal of Nanomedicine
Daewon Han,1,2,* Hyeji Lee,1,* Solji Lee,1 Kyubae Lee,3 Nam-Kyung Lee,4,5 Tae-Eun Jin,6 Junguee Lee,7 Jong-Seok Kim,1,2 Do Kyung Kim,8 Jongdae Shin,1,2 Hwan-Woo Park1,2 1Department of Cell Biology, Konyang University College of Medicine ...
Han D, Lee H, Lee S, Lee K, Lee NK, Jin TE, Lee J, Kim JS, Kim DK, Shin J, Park HW   +10 more
doaj