Results 111 to 120 of about 14,886,212 (348)
International Journal of NanomedicineDaewon Han,1,2,* Hyeji Lee,1,* Solji Lee,1 Kyubae Lee,3 Nam-Kyung Lee,4,5 Tae-Eun Jin,6 Junguee Lee,7 Jong-Seok Kim,1,2 Do Kyung Kim,8 Jongdae Shin,1,2 Hwan-Woo Park1,2 1Department of Cell Biology, Konyang University College of Medicine ...
Han D +10 more
doaj
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
FEBS Letters, EarlyView.The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
The membrane curvature-inducing REEP1-4 proteins generate an ER-derived vesicular compartment
Nature CommunicationsThe endoplasmic reticulum (ER) is shaped by abundant membrane curvature-generating proteins that include the REEP family member REEP5. The REEP1 subfamily, consisting of four proteins in mammals (REEP1-4), is less abundant and lack a N-terminal region ...
Yoko Shibata +8 more
doaj +1 more source
3D Scaffolds to Study Basic Cell Biology
Advances in Materials, 2019 Mimicking the properties of the extracellular matrix is crucial for developing in vitro models of the physiological microenvironment of living cells.
M. Hippler +6 more
semanticscholar +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
STAR ProtocolsSummary: Human primary cardiomyocytes are a valuable in vitro model for studying human heart physiology and disease. Here, we present a protocol for the dissociation of adult human primary cardiomyocytes using a methylcellulose-supplemented digestion ...
Xun Shi, Yafei Huang, Bingying Zhou
doaj +1 more source
Human organoids: a new dimension in cell biology
Molecular Biology of the Cell, 2019 Organoids derived from stem cells or tissues in culture can develop into structures that resemble the in vivo anatomy and physiology of intact organs. Human organoid cultures provide the potential to study human development and model disease processes ...
R. Lehmann +9 more
semanticscholar +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
UBE2J2 is essential for the progression of meiosis prophase I during spermatogenesis in mice
iScienceSummary: The coordination of numerous proteins is necessary for spermatogenesis, including degradation through the ubiquitin-proteasome pathway. Ubiquitin binding enzyme E2 (UBE2J2) is involved in the degradation of endoplasmic reticulum-associated ...
Xiaochen Yu +7 more
doaj +1 more source